34 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (730 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (108 aa)
	POLD2	DNA polymerase delta subunit 2. (469 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	MEIOB	CDC24_OB3 domain-containing protein. (471 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (615 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
	RCBTB2	RCC1 and BTB domain-containing protein 2. (551 aa)
	Pold3	DNA polymerase delta subunit 3. (465 aa)
	POLD1	DNA polymerase delta 1, catalytic subunit. (933 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	RAD18	E3 ubiquitin-protein ligase RAD18. (501 aa)
	POLE3	DNA polymerase epsilon subunit 3. (147 aa)
	ENSFDAP00000016886	annotation not available (678 aa)
	DDB1	DNA damage-binding protein 1. (1140 aa)
	RFC4	Replication factor C subunit 4. (333 aa)
	Usp1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (748 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	Pold4	DNA polymerase delta subunit 4. (107 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	RPA3	Replication protein A 14 kDa subunit. (122 aa)
	RFC2	Replication factor C subunit 2. (316 aa)
	CUL4B	Cullin-4B; Belongs to the cullin family. (888 aa)
	ENSFDAP00000010315	annotation not available (645 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
	RCBTB1	RCC1 and BTB domain-containing protein 1. (531 aa)
	RFC1	Replication factor C subunit 1. (1141 aa)
	CUL4A	Cullin 4A. (594 aa)
	ATAD5	ATPase family AAA domain-containing protein 5. (1822 aa)
	WDR48	WD repeat-containing protein 48. (677 aa)
	ENSFDAP00000002920	annotation not available (87 aa)
	RFC5	Replication factor C subunit 5. (338 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	RPA2	Replication protein A 32 kDa subunit. (270 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	CUL4A	ENSFDAP00000006258	ENSFDAP00000006945	ATPase family AAA domain-containing protein 5.	Cullin 4A.	0.631
ATAD5	CUL4B	ENSFDAP00000006258	ENSFDAP00000010967	ATPase family AAA domain-containing protein 5.	Cullin-4B; Belongs to the cullin family.	0.631
ATAD5	DTL	ENSFDAP00000006258	ENSFDAP00000016957	ATPase family AAA domain-containing protein 5.	Denticleless E3 ubiquitin protein ligase homolog.	0.858
ATAD5	ENSFDAP00000010315	ENSFDAP00000006258	ENSFDAP00000010315	ATPase family AAA domain-containing protein 5.	annotation not available	0.772
ATAD5	ENSFDAP00000016886	ENSFDAP00000006258	ENSFDAP00000016886	ATPase family AAA domain-containing protein 5.	annotation not available	0.772
ATAD5	MEIOB	ENSFDAP00000006258	ENSFDAP00000021681	ATPase family AAA domain-containing protein 5.	CDC24_OB3 domain-containing protein.	0.843
ATAD5	PCNA	ENSFDAP00000006258	ENSFDAP00000000579	ATPase family AAA domain-containing protein 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.990
ATAD5	POLD1	ENSFDAP00000006258	ENSFDAP00000019600	ATPase family AAA domain-containing protein 5.	DNA polymerase delta 1, catalytic subunit.	0.873
ATAD5	POLD2	ENSFDAP00000006258	ENSFDAP00000022279	ATPase family AAA domain-containing protein 5.	DNA polymerase delta subunit 2.	0.748
ATAD5	POLE	ENSFDAP00000006258	ENSFDAP00000009411	ATPase family AAA domain-containing protein 5.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.915
ATAD5	POLE2	ENSFDAP00000006258	ENSFDAP00000021169	ATPase family AAA domain-containing protein 5.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.866
ATAD5	POLE3	ENSFDAP00000006258	ENSFDAP00000018285	ATPase family AAA domain-containing protein 5.	DNA polymerase epsilon subunit 3.	0.825
ATAD5	Pold4	ENSFDAP00000006258	ENSFDAP00000013358	ATPase family AAA domain-containing protein 5.	DNA polymerase delta subunit 4.	0.518
ATAD5	RAD18	ENSFDAP00000006258	ENSFDAP00000018344	ATPase family AAA domain-containing protein 5.	E3 ubiquitin-protein ligase RAD18.	0.877
ATAD5	RFC1	ENSFDAP00000006258	ENSFDAP00000007472	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 1.	0.687
ATAD5	RFC2	ENSFDAP00000006258	ENSFDAP00000011100	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 2.	0.993
ATAD5	RFC3	ENSFDAP00000006258	ENSFDAP00000011384	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 3.	0.995
ATAD5	RFC4	ENSFDAP00000006258	ENSFDAP00000016432	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 4.	0.994
ATAD5	RFC5	ENSFDAP00000006258	ENSFDAP00000001452	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 5.	0.994
ATAD5	RPA1	ENSFDAP00000006258	ENSFDAP00000021416	ATPase family AAA domain-containing protein 5.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.843