49 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKCE	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (736 aa)
	GRB7	Growth factor receptor-bound protein 7. (536 aa)
	ERBB4	Receptor tyrosine-protein kinase erbB-4. (1280 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	USP8	Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1080 aa)
	Nrg3	Pro-neuregulin-3, membrane-bound isoform. (414 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
	GAB1	GRB2-associated-binding protein 1. (698 aa)
	SOS1	Son of sevenless like protein 1. (1289 aa)
	SRC	SRC proto-oncogene, non-receptor tyrosine kinase. (476 aa)
	Memo1	Protein MEMO1. (276 aa)
	STUB1	STIP1 homology and U box-containing protein 1. (250 aa)
	Ptpn18	Tyrosine-protein phosphatase non-receptor type 18. (419 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	RNF41	E3 ubiquitin-protein ligase NRDP1. (317 aa)
	EGFR	Receptor protein-tyrosine kinase. (1168 aa)
	BTC	Probetacellulin. (179 aa)
	ENSFDAP00000002920	annotation not available (87 aa)
	ERBIN	Protein LAP2. (1460 aa)
	ENSFDAP00000001760	annotation not available (275 aa)
	AKT2	RAC-beta serine/threonine-protein kinase. (481 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	RHOA	Transforming protein RhoA. (193 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	CSDE1	Cold shock domain-containing protein E1. (798 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
	SHC1	SHC-transforming protein 1. (583 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A. (1198 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	H920_19261	Pro-neuregulin-2, membrane-bound isoform. (251 aa)
	CDC37	Cell division cycle 37. (377 aa)
	NRG4	Pro-neuregulin-4, membrane-bound isoform. (84 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	CUL5	Cullin-5; Belongs to the cullin family. (785 aa)
	ERBB3	Receptor tyrosine-protein kinase erbB-3. (1308 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	PTK6	Protein-tyrosine kinase 6. (451 aa)
	EGF	Pro-epidermal growth factor. (1155 aa)
	KRAS	GTPase HRas. (189 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1212 aa)
	EREG	Proepiregulin. (163 aa)
	NRG1	Pro-neuregulin-1, membrane-bound isoform. (699 aa)
	HRAS	HRas proto-oncogene, GTPase. (191 aa)
	MATK	Megakaryocyte-associated tyrosine kinase. (333 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	AKT3	Non-specific serine/threonine protein kinase. (480 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1206 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFDAP00000004053	ENSFDAP00000023091	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RAC-beta serine/threonine-protein kinase.	0.950
AKT1	AKT3	ENSFDAP00000004053	ENSFDAP00000011080	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.887
AKT1	CDC37	ENSFDAP00000004053	ENSFDAP00000018762	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cell division cycle 37.	0.954
AKT1	CSDE1	ENSFDAP00000004053	ENSFDAP00000021201	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cold shock domain-containing protein E1.	0.510
AKT1	EGF	ENSFDAP00000004053	ENSFDAP00000000426	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Pro-epidermal growth factor.	0.637
AKT1	EGFR	ENSFDAP00000004053	ENSFDAP00000003693	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.561
AKT1	ENSFDAP00000002920	ENSFDAP00000004053	ENSFDAP00000002920	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	annotation not available	0.465
AKT1	ERBB2	ENSFDAP00000004053	ENSFDAP00000013284	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.444
AKT1	ERBB3	ENSFDAP00000004053	ENSFDAP00000016044	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor tyrosine-protein kinase erbB-3.	0.626
AKT1	ERBB4	ENSFDAP00000004053	ENSFDAP00000008733	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor tyrosine-protein kinase erbB-4.	0.487
AKT1	FYN	ENSFDAP00000004053	ENSFDAP00000011404	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.686
AKT1	GAB1	ENSFDAP00000004053	ENSFDAP00000006570	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	GRB2-associated-binding protein 1.	0.461
AKT1	GRB2	ENSFDAP00000004053	ENSFDAP00000004772	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Growth factor receptor-bound protein 2.	0.733
AKT1	HRAS	ENSFDAP00000004053	ENSFDAP00000012325	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HRas proto-oncogene, GTPase.	0.559
AKT1	KRAS	ENSFDAP00000004053	ENSFDAP00000013445	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	GTPase HRas.	0.559
AKT1	MATK	ENSFDAP00000004053	ENSFDAP00000011601	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Megakaryocyte-associated tyrosine kinase.	0.580
AKT1	NRAS	ENSFDAP00000004053	ENSFDAP00000023205	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NRAS proto-oncogene, GTPase.	0.559
AKT1	NRG1	ENSFDAP00000004053	ENSFDAP00000012621	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Pro-neuregulin-1, membrane-bound isoform.	0.425
AKT1	PIK3CA	ENSFDAP00000004053	ENSFDAP00000020092	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.962
AKT1	PIK3R1	ENSFDAP00000004053	ENSFDAP00000020905	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit alpha.	0.946