71 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOTCH4	Uncharacterized protein. (1707 aa)
	EP300	Histone acetyltransferase p300. (2430 aa)
	NOTCH2	Uncharacterized protein. (2418 aa)
	ENSFDAP00000007008	annotation not available (309 aa)
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10. (729 aa)
	POFUT1	GDP-fucose protein O-fucosyltransferase 1. (390 aa)
	HEY1	Hairy/enhancer-of-split related with YRPW motif protein 1. (304 aa)
	PBX2	Pre-B-cell leukemia transcription factor 2. (423 aa)
	RFNG	Beta-1,3-N-acetylglucosaminyltransferase radical fringe. (268 aa)
	Mamld1	Mastermind-like domain-containing protein 1. (747 aa)
	DNER	Delta/notch like EGF repeat containing. (641 aa)
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (731 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
	MAML1	Mastermind-like protein 1. (849 aa)
	PBX1	Pre-B-cell leukemia transcription factor 1. (391 aa)
	ELF3	ETS-related transcription factor Elf-3. (273 aa)
	IKZF3	Zinc finger protein Aiolos. (508 aa)
	IKZF1	DNA-binding protein Ikaros. (512 aa)
	LFNG	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe. (245 aa)
	H920_14855	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (262 aa)
	IKZF4	Zinc finger protein Eos. (653 aa)
	EHF	ETS like proteinous factor. (300 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	MAML2	Mastermind-like protein 2. (989 aa)
	POGLUT1	Protein O-glucosyltransferase 1. (392 aa)
	LOC104870598	Histone H2B type 1-K-like. (126 aa)
	H920_06884	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
	Ybx1	Coiled-coil domain-containing protein 30. (268 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1106 aa)
	NEURL1B	E3 ubiquitin-protein ligase NEURL1B. (304 aa)
	H2BC12	H2B clustered histone 12. (126 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	PSENEN	Gamma-secretase subunit PEN-2. (101 aa)
	DLL4	Delta like canonical Notch ligand 4. (851 aa)
	LOC104853662	Nuclease-sensitive element-binding protein 1. (296 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1191 aa)
	APH1B	Gamma-secretase subunit APH-1B. (257 aa)
	TNRC6B	Trinucleotide repeat-containing gene 6B protein. (1811 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	PBX3	Pre-B-cell leukemia transcription factor 3. (367 aa)
	CRB1	Crumbs like protein 1. (1271 aa)
	Ywhaz	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
	DLK1	Delta like non-canonical Notch ligand 1. (356 aa)
	DTX1	Protein deltex-4. (510 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	TMED2	Transmembrane p24 trafficking protein 2. (116 aa)
	Lrba	Lipopolysaccharide-responsive and beige-like anchor protein. (749 aa)
	DTX2	Protein deltex-2. (619 aa)
	FCER2	Fc fragment of IgE receptor II. (332 aa)
	NCSTN	Nicastrin. (709 aa)
	IKZF2	Zinc finger protein Helios. (532 aa)
	EGF	Pro-epidermal growth factor. (1155 aa)
	NBEA	Neurobeachin. (2881 aa)
	MIB1	E3 ubiquitin-protein ligase MIB1. (929 aa)
	HES1	Transcription factor HES-1. (278 aa)
	HEYL	Hairy/enhancer-of-split related with YRPW motif-like protein. (329 aa)
	ENSFDAP00000002920	annotation not available (87 aa)
	EGFR	Receptor protein-tyrosine kinase. (1168 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	NEURL1	Neuralized-like protein 1A. (355 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (671 aa)
	MFNG	Beta-1,3-N-acetylglucosaminyltransferase manic fringe. (321 aa)
	DLGAP5	Disks large-associated protein 5. (835 aa)
	NOTCH3	Notch receptor 3. (2095 aa)
	NOTCH1	Uncharacterized protein. (2309 aa)
	MOV10	Putative helicase MOV-10. (1002 aa)
	TACC3	Transforming acidic coiled-coil-containing protein 3. (768 aa)
	H920_14216	ETS-related transcription factor Elf-3. (494 aa)
	WWP2	E3 ubiquitin-protein ligase. (870 aa)
	APH1A	Gamma-secretase subunit APH-1A. (265 aa)
	CNTN1	Contactin-1. (1016 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	APH1A	ENSFDAP00000007509	ENSFDAP00000019695	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit APH-1A.	0.501
ADAM10	CRB1	ENSFDAP00000007509	ENSFDAP00000019425	Disintegrin and metalloproteinase domain-containing protein 10.	Crumbs like protein 1.	0.527
ADAM10	DLL1	ENSFDAP00000007509	ENSFDAP00000005058	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.760
ADAM10	DLL4	ENSFDAP00000007509	ENSFDAP00000017077	Disintegrin and metalloproteinase domain-containing protein 10.	Delta like canonical Notch ligand 4.	0.660
ADAM10	EGF	ENSFDAP00000007509	ENSFDAP00000000426	Disintegrin and metalloproteinase domain-containing protein 10.	Pro-epidermal growth factor.	0.477
ADAM10	JAG1	ENSFDAP00000007509	ENSFDAP00000017517	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.626
ADAM10	JAG2	ENSFDAP00000007509	ENSFDAP00000015702	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.632
ADAM10	NCSTN	ENSFDAP00000007509	ENSFDAP00000000329	Disintegrin and metalloproteinase domain-containing protein 10.	Nicastrin.	0.675
ADAM10	NOTCH1	ENSFDAP00000007509	ENSFDAP00000005618	Disintegrin and metalloproteinase domain-containing protein 10.	Uncharacterized protein.	0.765
ADAM10	NOTCH2	ENSFDAP00000007509	ENSFDAP00000005981	Disintegrin and metalloproteinase domain-containing protein 10.	Uncharacterized protein.	0.746
ADAM10	NOTCH3	ENSFDAP00000007509	ENSFDAP00000005542	Disintegrin and metalloproteinase domain-containing protein 10.	Notch receptor 3.	0.610
ADAM10	NOTCH4	ENSFDAP00000007509	ENSFDAP00000002658	Disintegrin and metalloproteinase domain-containing protein 10.	Uncharacterized protein.	0.476
ADAM10	PSEN1	ENSFDAP00000007509	ENSFDAP00000016611	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.720
ADAM10	PSEN2	ENSFDAP00000007509	ENSFDAP00000009904	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.709
ADAM10	PSENEN	ENSFDAP00000007509	ENSFDAP00000016929	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit PEN-2.	0.633
AKT1	CRB1	ENSFDAP00000004053	ENSFDAP00000019425	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Crumbs like protein 1.	0.500
AKT1	DLL1	ENSFDAP00000004053	ENSFDAP00000005058	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.496
AKT1	DLL4	ENSFDAP00000004053	ENSFDAP00000017077	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Delta like canonical Notch ligand 4.	0.519
AKT1	DNER	ENSFDAP00000004053	ENSFDAP00000009647	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Delta/notch like EGF repeat containing.	0.495
AKT1	EGF	ENSFDAP00000004053	ENSFDAP00000000426	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Pro-epidermal growth factor.	0.637