STRINGSTRING
CHMP4A CHMP4A RRAGC RRAGC MDP1 MDP1 CETN3 CETN3 PINK1 PINK1 TOMM40L TOMM40L ENSFDAP00000022809 ENSFDAP00000022809 DYNLL2 DYNLL2 LAMTOR2 LAMTOR2 GABARAPL2 GABARAPL2 UBA52 UBA52 LOC104851822 LOC104851822 RB1CC1 RB1CC1 FUNDC1 FUNDC1 CFTR CFTR Mfn1 Mfn1 LOC104863283 LOC104863283 LOC104868700 LOC104868700 Ly6g5b Ly6g5b DYNC1I1 DYNC1I1 FNDC3A FNDC3A TOMM7 TOMM7 CSNK2B CSNK2B PRKAB1 PRKAB1 H920_05903 H920_05903 NBR1 NBR1 ULK1 ULK1 TOMM40 TOMM40 WIPI1 WIPI1 TOMM20 TOMM20 Vdac1 Vdac1 VIM VIM TXNDC11 TXNDC11 LOC104861363 LOC104861363 DYNC1LI1 DYNC1LI1 DYNC1H1 DYNC1H1 Dynll1 Dynll1 Ubc Ubc PRKAA2 PRKAA2 LOC104861958 LOC104861958 Map1lc3b Map1lc3b Tm9sf1 Tm9sf1 ENSFDAP00000017826 ENSFDAP00000017826 ENSFDAP00000017776 ENSFDAP00000017776 GABARAPL1 GABARAPL1 LOC104849456 LOC104849456 SQSTM1 SQSTM1 ATG4D ATG4D PGAM5 PGAM5 CHMP7 CHMP7 C17orf75 C17orf75 MTOR MTOR PLIN2 PLIN2 TUBA8 TUBA8 PRKAG3 PRKAG3 ULK2 ULK2 CRYBB3 CRYBB3 TOMM70 TOMM70 ATG9B ATG9B PEX5L PEX5L RRAGD RRAGD LOC104875392 LOC104875392 LOC104859867 LOC104859867 LAMTOR4 LAMTOR4 CHMP6 CHMP6 H920_07688 H920_07688 RPS27A RPS27A Kiaa1671 Kiaa1671 USP30 USP30 ATG10 ATG10 PARK7 PARK7 Atg5 Atg5 CHMP4C CHMP4C ILRUN ILRUN UBE2V1 UBE2V1 RHEB RHEB MTERF3 MTERF3 ATM ATM H920_18855 H920_18855 TOMM22 TOMM22 ENSFDAP00000012339 ENSFDAP00000012339 FUNDC2 FUNDC2 RHEBL1 RHEBL1 ENSFDAP00000011772 ENSFDAP00000011772 TUBE1 TUBE1 TUBA4A TUBA4A Atg9a Atg9a ENSFDAP00000011603 ENSFDAP00000011603 H920_13202 H920_13202 HDAC6 HDAC6 MAP1LC3A MAP1LC3A TSC2 TSC2 CHMP2B CHMP2B Gsap Gsap RRAGB RRAGB LOC104861955 LOC104861955 ATG101 ATG101 H920_06774 H920_06774 H920_07462 H920_07462 FNDC3B FNDC3B UVRAG UVRAG ATG16L1 ATG16L1 ARL13B ARL13B Lamtor3 Lamtor3 Csnk2a1 Csnk2a1 H920_13791 H920_13791 ATG7 ATG7 TUBB4A TUBB4A MFN2 MFN2 DYNC1I2 DYNC1I2 Tomm5 Tomm5 ENSFDAP00000007850 ENSFDAP00000007850 ENSFDAP00000007466 ENSFDAP00000007466 PRKAG2 PRKAG2 LOC104859914 LOC104859914 PEX5 PEX5 Lamtor5 Lamtor5 ENSFDAP00000006648 ENSFDAP00000006648 ATG12 ATG12 PRKAG1 PRKAG1 TSC1 TSC1 ENSFDAP00000006077 ENSFDAP00000006077 CSNK2A2 CSNK2A2 MTMR3 MTMR3 IFT88 IFT88 TUBB1 TUBB1 ATG4B ATG4B PIK3R4 PIK3R4 WDR45B WDR45B GABARAP GABARAP PRKAB2 PRKAB2 ATG16L2 ATG16L2 ATG14 ATG14 Becn1 Becn1 ATG4C ATG4C PIK3C3 PIK3C3 Wdr45 Wdr45 RPTOR RPTOR CHMP2A CHMP2A WIPI2 WIPI2 ENSFDAP00000002920 ENSFDAP00000002920 H920_06518 H920_06518 ENSFDAP00000002789 ENSFDAP00000002789 TOMM6 TOMM6 DYNC1LI2 DYNC1LI2 PRKAA1 PRKAA1 ENSFDAP00000002122 ENSFDAP00000002122 LOC104861364 LOC104861364 AMBRA1 AMBRA1 Tubb4b Tubb4b ATG4A ATG4A ATG3 ATG3 MTMR14 MTMR14 MLST8 MLST8 H920_17227 H920_17227 SLC38A9 SLC38A9 LAMTOR1 LAMTOR1 CHMP4B CHMP4B ATG13 ATG13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHMP4ACharged multivesicular body protein 4A. (206 aa)
RRAGCRas-related GTP-binding protein C. (344 aa)
MDP1Magnesium-dependent phosphatase 1. (161 aa)
CETN3Centrin-3. (231 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (446 aa)
TOMM40LMitochondrial import receptor subunit TOM40B. (308 aa)
ENSFDAP00000022809annotation not available (250 aa)
DYNLL2Dynein light chain. (89 aa)
LAMTOR2Ragulator complex protein LAMTOR2. (125 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
UBA52KxDL motif containing 1. (232 aa)
LOC104851822Dynein light chain. (89 aa)
RB1CC1RB1-inducible coiled-coil protein 1. (1592 aa)
FUNDC1FUN14 domain-containing protein 1. (211 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
Mfn1Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (239 aa)
LOC104863283Charged multivesicular body protein 3. (221 aa)
LOC104868700Uncharacterized protein. (301 aa)
Ly6g5bUncharacterized protein. (193 aa)
DYNC1I1Cytoplasmic dynein 1 intermediate chain 1. (628 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1198 aa)
TOMM7Mitochondrial import receptor subunit TOM7 like protein. (55 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (183 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (270 aa)
H920_05903Charged multivesicular body protein 3. (197 aa)
NBR1Next to BRCA1 gene 1 protein. (986 aa)
ULK1Serine/threonine-protein kinase ULK1. (1043 aa)
TOMM40Mitochondrial import receptor subunit TOM40 like protein. (314 aa)
WIPI1WD repeat domain phosphoinositide-interacting protein 1. (419 aa)
TOMM20Mitochondrial import receptor subunit TOM20 like protein. (145 aa)
Vdac1Voltage-dependent anion-selective channel protein 1. (285 aa)
VIMVimentin; Belongs to the intermediate filament family. (411 aa)
TXNDC11Thioredoxin domain-containing protein 11. (866 aa)
LOC104861363Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (444 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (496 aa)
DYNC1H1Cytoplasmic dynein 1 heavy chain 1. (4606 aa)
Dynll1Dynein light chain. (89 aa)
UbcPolyubiquitin-B. (235 aa)
PRKAA2Non-specific serine/threonine protein kinase. (545 aa)
LOC104861958Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
Map1lc3bMicrotubule associated protein 1 light chain 3 beta. (112 aa)
Tm9sf1Transmembrane 9 superfamily member 1. (606 aa)
ENSFDAP00000017826annotation not available (133 aa)
ENSFDAP00000017776annotation not available (72 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1. (113 aa)
LOC104849456E3 ubiquitin-protein ligase parkin. (243 aa)
SQSTM1Sequestosome-1. (400 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (477 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (244 aa)
CHMP7Charged multivesicular body protein 7. (448 aa)
C17orf75Uncharacterized protein. (394 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2551 aa)
PLIN2Perilipin; Belongs to the perilipin family. (337 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (488 aa)
ULK2Serine/threonine-protein kinase ULK2. (1057 aa)
CRYBB3Beta-crystallin B3; Belongs to the beta/gamma-crystallin family. (166 aa)
TOMM70Mitochondrial import receptor subunit TOM70. (599 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (852 aa)
PEX5LPEX5-related protein. (596 aa)
RRAGDRas-related GTP-binding protein D. (400 aa)
LOC104875392Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC104859867Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LAMTOR4Uncharacterized protein. (99 aa)
CHMP6Charged multivesicular body protein 6. (192 aa)
H920_07688Voltage-dependent anion-selective channel protein 1. (239 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
Kiaa1671Tankyrase_bdg_C domain-containing protein. (387 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (382 aa)
ATG10Autophagy related 10. (219 aa)
PARK7Protein DJ-1. (189 aa)
Atg5Autophagy protein 5; Involved in autophagic vesicle formation. (198 aa)
CHMP4CCharged multivesicular body protein 4c. (229 aa)
ILRUNN_BRCA1_IG domain-containing protein. (238 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (175 aa)
RHEBGTP-binding protein Rheb. (184 aa)
MTERF3mTERF domain-containing protein 1, mitochondrial. (423 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3061 aa)
H920_18855Tubulin alpha-1C chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (246 aa)
TOMM22Mitochondrial import receptor subunit TOM22 like protein. (142 aa)
ENSFDAP00000012339annotation not available (73 aa)
FUNDC2FUN14 domain containing 2. (164 aa)
RHEBL1GTPase RhebL1. (183 aa)
ENSFDAP00000011772annotation not available (273 aa)
TUBE1Tubulin epsilon chain; Belongs to the tubulin family. (476 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
Atg9aAutophagy-related protein 9A. (839 aa)
ENSFDAP00000011603annotation not available (308 aa)
H920_13202Microtubule-associated proteins 1A/1B light chain 3C. (202 aa)
HDAC6Histone deacetylase 6. (1108 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (89 aa)
TSC2Tuberin. (1743 aa)
CHMP2BCharged multivesicular body protein 2b. (213 aa)
GsapGamma-secretase-activating protein. (175 aa)
RRAGBRas-related GTP-binding protein B. (374 aa)
LOC104861955Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
ATG101Autophagy-related protein 101. (218 aa)
H920_06774Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (446 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
UVRAGUV radiation resistance-associated gene protein. (675 aa)
ATG16L1Autophagy-related protein 16-1. (624 aa)
ARL13BADP-ribosylation factor-like protein 13B. (430 aa)
Lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
Csnk2a1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
H920_13791Uncharacterized protein. (176 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (699 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (436 aa)
MFN2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (762 aa)
DYNC1I2Cytoplasmic dynein 1 intermediate chain 2. (638 aa)
Tomm5Mitochondrial import receptor subunit TOM5 like protein. (51 aa)
ENSFDAP00000007850annotation not available (114 aa)
ENSFDAP00000007466annotation not available (44 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2. (541 aa)
LOC104859914Tubulin alpha-3 chain-like. (297 aa)
PEX5Peroxisomal targeting signal 1 receptor. (640 aa)
Lamtor5Hepatitis B virus X-interacting protein like protein. (131 aa)
ENSFDAP00000006648annotation not available (129 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (141 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1. (330 aa)
TSC1Hamartin. (1168 aa)
ENSFDAP00000006077annotation not available (101 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (315 aa)
MTMR3Myotubularin-related protein 3. (1211 aa)
IFT88Intraflagellar transport protein 88 like protein. (825 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (391 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1382 aa)
WDR45BWD repeat domain phosphoinositide-interacting protein 3. (344 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2. (257 aa)
ATG16L2Autophagy-related protein 16-2. (624 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
Becn1Beclin-1. (448 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (892 aa)
Wdr45WD repeat domain phosphoinositide-interacting protein 4. (360 aa)
RPTORRegulatory-associated protein of mTOR. (1335 aa)
CHMP2ACharged multivesicular body protein 2a. (222 aa)
WIPI2WD repeat domain phosphoinositide-interacting protein 2. (418 aa)
ENSFDAP00000002920annotation not available (87 aa)
H920_06518Putative tubulin beta chain-like protein ENSP00000290377; Belongs to the tubulin family. (284 aa)
ENSFDAP00000002789annotation not available (79 aa)
TOMM6Translocase of outer mitochondrial membrane 6. (74 aa)
DYNC1LI2Dynein cytoplasmic 1 light intermediate chain 2. (456 aa)
PRKAA1Non-specific serine/threonine protein kinase. (516 aa)
ENSFDAP00000002122annotation not available (80 aa)
LOC104861364Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (423 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1235 aa)
Tubb4bTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (391 aa)
ATG3Autophagy-related protein 3. (313 aa)
MTMR14Myotubularin-related protein 14. (626 aa)
MLST8Target of rapamycin complex subunit LST8. (326 aa)
H920_17227Beclin-1. (445 aa)
SLC38A9Putative sodium-coupled neutral amino acid transporter 9. (559 aa)
LAMTOR1Ragulator complex protein LAMTOR1. (161 aa)
CHMP4BCharged multivesicular body protein 4b. (224 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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