STRINGSTRING
TAB2 TAB2 DUSP7 DUSP7 Ikbip Ikbip Tonsl Tonsl UBA52 UBA52 ECSIT ECSIT TAB3 TAB3 ATF1 ATF1 H920_19873 H920_19873 AGER AGER LOC104865314 LOC104865314 FOS FOS DUSP6 DUSP6 MAP2K3 MAP2K3 IKBKG IKBKG MAPK10 MAPK10 RPS6KA3 RPS6KA3 MAPK1 MAPK1 H920_16633 H920_16633 LRRC14 LRRC14 NFKBIB NFKBIB MAPK15 MAPK15 MAPK3 MAPK3 RELCH RELCH RIPK2 RIPK2 H920_06373 H920_06373 ATF2 ATF2 PPP2R1B PPP2R1B NOD1 NOD1 ENSFDAP00000018414 ENSFDAP00000018414 Ubc Ubc Hmgb1 Hmgb1 NFKB1 NFKB1 ENSFDAP00000017776 ENSFDAP00000017776 Ppp2ca Ppp2ca MAP2K7 MAP2K7 CASP8 CASP8 Chuk Chuk N4BP1 N4BP1 NFKB2 NFKB2 PELI3 PELI3 NFKBIA NFKBIA TRAF6 TRAF6 NOD2 NOD2 MAP3K7 MAP3K7 NKIRAS1 NKIRAS1 FNBP4 FNBP4 H920_02493 H920_02493 CREB5 CREB5 RPS27A RPS27A UBE2V1 UBE2V1 RPS6KA5 RPS6KA5 VRK3 VRK3 MAPKAPK3 MAPKAPK3 PPP2R5D PPP2R5D LRRC45 LRRC45 USP14 USP14 Dusp3 Dusp3 PPP2CB PPP2CB MAPK9 MAPK9 APP APP MAPK11 MAPK11 PPP4R1 PPP4R1 ENSFDAP00000010317 ENSFDAP00000010317 MAP3K1 MAP3K1 H920_07462 H920_07462 ELK1 ELK1 JUN JUN PELI2 PELI2 TIRAP TIRAP CREB1 CREB1 SIGIRR SIGIRR RPS6KA2 RPS6KA2 MAP2K6 MAP2K6 KHNYN KHNYN PPP4R4 PPP4R4 TIFA TIFA ENSFDAP00000006648 ENSFDAP00000006648 LRRC74B LRRC74B RELA RELA DUSP4 DUSP4 NLRP6 NLRP6 MAPK14 MAPK14 MAPK7 MAPK7 ALPK1 ALPK1 NLRC5 NLRC5 ENSFDAP00000004787 ENSFDAP00000004787 LRRC74A LRRC74A MAPK8 MAPK8 ENSFDAP00000004169 ENSFDAP00000004169 Atf7 Atf7 RPS6KA1 RPS6KA1 LRRC71 LRRC71 ENSFDAP00000002920 ENSFDAP00000002920 IKBKB IKBKB S100B S100B Ppp2r1a Ppp2r1a IRAK1 IRAK1 PELI1 PELI1 MAPKAPK2 MAPKAPK2 NLRX1 NLRX1 Map2k4 Map2k4 Tmem189 Tmem189 NKIRAS2 NKIRAS2 TRAF2 TRAF2 LRRC34 LRRC34 TAB1 TAB1 Map3k20 Map3k20 ENSFDAP00000000261 ENSFDAP00000000261 ENSFDAP00000000144 ENSFDAP00000000144 ENSFDAP00000000117 ENSFDAP00000000117 Usp18 Usp18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (363 aa)
IkbipIKBKB interacting protein. (339 aa)
TonslTonsoku-like protein. (64 aa)
UBA52KxDL motif containing 1. (232 aa)
ECSITEvolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. (434 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1. (309 aa)
H920_19873Serum amyloid A-4 protein. (129 aa)
AGERAdvanced glycosylation end product-specific receptor. (418 aa)
LOC104865314Serine/threonine-protein phosphatase 4 regulatory subunit 1. (941 aa)
FOSProto-oncogene c-Fos. (380 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
IKBKGNF-kappa-B essential modulator. (417 aa)
MAPK10Mitogen-activated protein kinase. (478 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (727 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
H920_16633High mobility group protein B1. (166 aa)
LRRC14Leucine-rich repeat-containing protein 14. (493 aa)
NFKBIBNF-kappa-B inhibitor beta. (358 aa)
MAPK15Mitogen-activated protein kinase. (517 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
RELCHLisH domain and HEAT repeat-containing protein KIAA1468. (1216 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (482 aa)
H920_06373High mobility group-T protein. (197 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (505 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (653 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (824 aa)
ENSFDAP00000018414annotation not available (666 aa)
UbcPolyubiquitin-B. (235 aa)
Hmgb1High mobility group protein B1. (215 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (894 aa)
ENSFDAP00000017776annotation not available (72 aa)
Ppp2caSerine/threonine-protein phosphatase. (275 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7. (427 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (462 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
N4BP1NEDD4-binding protein 1. (825 aa)
NFKB2Nuclear factor kappa B subunit 2. (752 aa)
PELI3Pellino E3 ubiquitin protein ligase family member 3. (445 aa)
NFKBIANF-kappa-B inhibitor alpha. (224 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1097 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (606 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1. (112 aa)
FNBP4Formin binding protein 4. (916 aa)
H920_02493Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
CREB5cAMP responsive element binding protein 5. (508 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (175 aa)
RPS6KA5Ribosomal protein S6 kinase. (810 aa)
VRK3Inactive serine/threonine-protein kinase VRK3. (453 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (585 aa)
LRRC45Leucine-rich repeat-containing protein 45. (662 aa)
USP14Ubiquitin specific peptidase 14. (440 aa)
Dusp3Dual specificity phosphatase 3. (117 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
APPAmyloid beta A4 protein. (766 aa)
MAPK11Mitogen-activated protein kinase 11. (325 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (928 aa)
ENSFDAP00000010317annotation not available (274 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1347 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
ELK1ETS domain-containing protein Elk-1. (427 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (254 aa)
PELI2Protein pellino like protein 2. (351 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein. (209 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (341 aa)
SIGIRRSingle Ig and TIR domain containing. (408 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
KHNYNProtein KHNYN. (670 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4. (833 aa)
TIFATRAF-interacting protein with FHA domain-containing protein A. (185 aa)
ENSFDAP00000006648annotation not available (129 aa)
LRRC74BLeucine rich repeat containing 74B. (378 aa)
RELATranscription factor p65. (545 aa)
DUSP4Dual specificity phosphatase 4. (394 aa)
NLRP6NLR family pyrin domain containing 6. (808 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (808 aa)
ALPK1Alpha-protein kinase 1. (1003 aa)
NLRC5Protein NLRC5. (1784 aa)
ENSFDAP00000004787annotation not available (192 aa)
LRRC74AUncharacterized protein. (476 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSFDAP00000004169annotation not available (234 aa)
Atf7Cyclic AMP-dependent transcription factor ATF-7. (483 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
LRRC71Leucine-rich repeat-containing protein 71. (462 aa)
ENSFDAP00000002920annotation not available (87 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
S100BProtein S100-B; Belongs to the S-100 family. (92 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (573 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (453 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (399 aa)
NLRX1NLR family member X1. (972 aa)
Map2k4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (381 aa)
Tmem189Transmembrane protein 189. (229 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
LRRC34Leucine-rich repeat-containing protein 34. (402 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
Map3k20Mitogen-activated protein kinase kinase kinase MLT. (671 aa)
ENSFDAP00000000261annotation not available (93 aa)
ENSFDAP00000000144annotation not available (263 aa)
ENSFDAP00000000117annotation not available (223 aa)
Usp18Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (60 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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