STRINGSTRING
MEFV MEFV Map3k20 Map3k20 TAB1 TAB1 Tmem189 Tmem189 LOC104849418 LOC104849418 TAB2 TAB2 NLRP3 NLRP3 MAPK13 MAPK13 TXNIP TXNIP ENSFDAP00000002920 ENSFDAP00000002920 BIRC3 BIRC3 Txn Txn LOC104874823 LOC104874823 AAMP AAMP ENSFDAP00000004787 ENSFDAP00000004787 ARRDC3 ARRDC3 ARRDC5 ARRDC5 MAPK14 MAPK14 PSTPIP1 PSTPIP1 TXNDC8 TXNDC8 ENSFDAP00000006648 ENSFDAP00000006648 Nlrp1 Nlrp1 MAP2K6 MAP2K6 ENSFDAP00000009759 ENSFDAP00000009759 H920_07462 H920_07462 MAPK11 MAPK11 NME8 NME8 BCL2L2 BCL2L2 UBE2V1 UBE2V1 CASP9 CASP9 RPS27A RPS27A MAP3K7 MAP3K7 NOD2 NOD2 ARRDC4 ARRDC4 TRAF6 TRAF6 RNH1 RNH1 CASP8 CASP8 LOC104874822 LOC104874822 BCL2L1 BCL2L1 Pycard Pycard ENSFDAP00000017776 ENSFDAP00000017776 PSTPIP2 PSTPIP2 Ubc Ubc NOD1 NOD1 PANX1 PANX1 P2RX7 P2RX7 RIPK2 RIPK2 TNFAIP3 TNFAIP3 CYLD CYLD IKBKG IKBKG CASP2 CASP2 ARRDC1 ARRDC1 TAB3 TAB3 UBA52 UBA52 NLRP14 NLRP14 SUGT1 SUGT1 BIRC2 BIRC2 MAPK12 MAPK12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEFVPyrin. (828 aa)
Map3k20Mitogen-activated protein kinase kinase kinase MLT. (671 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
Tmem189Transmembrane protein 189. (229 aa)
LOC104849418NACHT, LRR and PYD domains-containing protein 1. (1095 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
NLRP3NACHT, LRR and PYD domains-containing protein 3. (955 aa)
MAPK13Mitogen-activated protein kinase 13. (323 aa)
TXNIPThioredoxin-interacting protein. (391 aa)
ENSFDAP00000002920annotation not available (87 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (644 aa)
TxnThioredoxin. (105 aa)
LOC104874823Caspase-12; Belongs to the peptidase C14A family. (449 aa)
AAMPAngio-associated migratory cell protein. (436 aa)
ENSFDAP00000004787annotation not available (192 aa)
ARRDC3Arrestin domain-containing protein 3. (403 aa)
ARRDC5Arrestin domain-containing protein 5. (406 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
PSTPIP1Proline-serine-threonine phosphatase interacting protein 1. (417 aa)
TXNDC8Thioredoxin domain containing 8. (127 aa)
ENSFDAP00000006648annotation not available (129 aa)
Nlrp1NACHT, LRR and PYD domains-containing protein 1. (559 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
ENSFDAP00000009759annotation not available (105 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
MAPK11Mitogen-activated protein kinase 11. (325 aa)
NME8Thioredoxin domain-containing protein 3. (539 aa)
BCL2L2Polyadenylate-binding protein 2. (193 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (175 aa)
CASP9Caspase-9; Belongs to the peptidase C14A family. (406 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (606 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1097 aa)
ARRDC4Arrestin domain-containing protein 4. (235 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
RNH1Ribonuclease inhibitor. (456 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (462 aa)
LOC104874822Caspase-1; Belongs to the peptidase C14A family. (434 aa)
BCL2L1Bcl-2-like protein 1. (233 aa)
PycardApoptosis-associated speck-like protein containing a CARD. (122 aa)
ENSFDAP00000017776annotation not available (72 aa)
PSTPIP2Proline-serine-threonine phosphatase-interacting protein 2. (290 aa)
UbcPolyubiquitin-B. (235 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (824 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa)
P2RX7p2X purinoceptor 7. (583 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (482 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (755 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (951 aa)
IKBKGNF-kappa-B essential modulator. (417 aa)
CASP2Caspase-2; Belongs to the peptidase C14A family. (452 aa)
ARRDC1Arrestin domain-containing protein 1. (391 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
UBA52KxDL motif containing 1. (232 aa)
NLRP14NACHT, LRR and PYD domains-containing protein 14. (931 aa)
SUGT1Suppressor of G2 allele of SKP1 like protein. (336 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (618 aa)
MAPK12Mitogen-activated protein kinase 12. (316 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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