STRINGSTRING
LGMN LGMN DUSP7 DUSP7 Ikbip Ikbip TLR7 TLR7 UBE2D1 UBE2D1 Tonsl Tonsl UBA52 UBA52 ECSIT ECSIT TAB3 TAB3 ATF1 ATF1 H920_19873 H920_19873 AGER AGER LOC104865314 LOC104865314 FOS FOS DUSP6 DUSP6 MAP2K3 MAP2K3 IKBKG IKBKG MAPK10 MAPK10 CNPY4 CNPY4 RPS6KA3 RPS6KA3 MAPK1 MAPK1 H920_16633 H920_16633 LRRC14 LRRC14 NFKBIB NFKBIB MAPK15 MAPK15 MAPK3 MAPK3 RELCH RELCH CD14 CD14 RIPK2 RIPK2 GSDMA GSDMA H920_06373 H920_06373 ATF2 ATF2 Tlr3 Tlr3 PPP2R1B PPP2R1B LBP LBP NOD1 NOD1 ENSFDAP00000018414 ENSFDAP00000018414 Ubc Ubc Gsdme Gsdme Hmgb1 Hmgb1 TBK1 TBK1 NFKB1 NFKB1 ENSFDAP00000017776 ENSFDAP00000017776 IRF3 IRF3 Ppp2ca Ppp2ca MAP2K7 MAP2K7 CASP8 CASP8 Chuk Chuk N4BP1 N4BP1 IRF7 IRF7 LOC104863125 LOC104863125 NFKB2 NFKB2 PELI3 PELI3 NFKBIA NFKBIA TRAF6 TRAF6 CD180 CD180 NOD2 NOD2 MAP3K7 MAP3K7 NKIRAS1 NKIRAS1 FNBP4 FNBP4 CTSS CTSS H920_02493 H920_02493 CREB5 CREB5 RPS27A RPS27A CTSK CTSK LOC104865813 LOC104865813 CTSV CTSV EEA1 EEA1 TLR8 TLR8 UBE2V1 UBE2V1 RBSN RBSN RPS6KA5 RPS6KA5 VRK3 VRK3 GSDMD GSDMD MAPKAPK3 MAPKAPK3 PPP2R5D PPP2R5D LRRC45 LRRC45 USP14 USP14 UNC93A UNC93A Dusp3 Dusp3 TLR5 TLR5 PPP2CB PPP2CB TLR1 TLR1 MAPK9 MAPK9 APP APP MAPK11 MAPK11 PPP4R1 PPP4R1 ENSFDAP00000010317 ENSFDAP00000010317 MAP3K1 MAP3K1 H920_07462 H920_07462 ELK1 ELK1 JUN JUN PELI2 PELI2 BPIFC BPIFC TIRAP TIRAP CREB1 CREB1 SIGIRR SIGIRR RPS6KA2 RPS6KA2 MAP2K6 MAP2K6 LY86 LY86 ENSFDAP00000007247 ENSFDAP00000007247 KHNYN KHNYN PPP4R4 PPP4R4 TIFA TIFA TLR4 TLR4 ENSFDAP00000006648 ENSFDAP00000006648 LRRC74B LRRC74B RELA RELA CD36 CD36 SARM1 SARM1 DUSP4 DUSP4 NLRP6 NLRP6 ENSFDAP00000005475 ENSFDAP00000005475 S100A1 S100A1 MAPK14 MAPK14 MAPK7 MAPK7 APOB APOB ALPK1 ALPK1 PIK3R4 PIK3R4 NLRC5 NLRC5 PTPN4 PTPN4 ENSFDAP00000004787 ENSFDAP00000004787 SFTPD SFTPD LRRC74A LRRC74A MAPK8 MAPK8 ENSFDAP00000004169 ENSFDAP00000004169 CNPY3 CNPY3 Atf7 Atf7 LOC104865812 LOC104865812 PIK3C3 PIK3C3 TLR2 TLR2 RPS6KA1 RPS6KA1 LRRC71 LRRC71 UNC93B1 UNC93B1 ENSFDAP00000002920 ENSFDAP00000002920 BPI BPI IKBKB IKBKB HSP90B1 HSP90B1 CTSB CTSB S100B S100B Ppp2r1a Ppp2r1a IRAK1 IRAK1 TRAF3 TRAF3 PELI1 PELI1 MAPKAPK2 MAPKAPK2 NLRX1 NLRX1 Ikbke Ikbke TAB2 TAB2 Map2k4 Map2k4 Tmem189 Tmem189 NKIRAS2 NKIRAS2 TRAF2 TRAF2 LRRC34 LRRC34 PTPN11 PTPN11 TAB1 TAB1 Map3k20 Map3k20 ENSFDAP00000000261 ENSFDAP00000000261 LOC104855315 LOC104855315 ENSFDAP00000000144 ENSFDAP00000000144 TRAF5 TRAF5 ENSFDAP00000000117 ENSFDAP00000000117 TANK TANK Usp18 Usp18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LGMNLegumain. (436 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (363 aa)
IkbipIKBKB interacting protein. (339 aa)
TLR7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
TonslTonsoku-like protein. (64 aa)
UBA52KxDL motif containing 1. (232 aa)
ECSITEvolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. (434 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1. (309 aa)
H920_19873Serum amyloid A-4 protein. (129 aa)
AGERAdvanced glycosylation end product-specific receptor. (418 aa)
LOC104865314Serine/threonine-protein phosphatase 4 regulatory subunit 1. (941 aa)
FOSProto-oncogene c-Fos. (380 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
IKBKGNF-kappa-B essential modulator. (417 aa)
MAPK10Mitogen-activated protein kinase. (478 aa)
CNPY4Protein canopy like protein 4. (247 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (727 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
H920_16633High mobility group protein B1. (166 aa)
LRRC14Leucine-rich repeat-containing protein 14. (493 aa)
NFKBIBNF-kappa-B inhibitor beta. (358 aa)
MAPK15Mitogen-activated protein kinase. (517 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
RELCHLisH domain and HEAT repeat-containing protein KIAA1468. (1216 aa)
CD14Monocyte differentiation antigen CD14. (383 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (482 aa)
GSDMAGasdermin-A. (434 aa)
H920_06373High mobility group-T protein. (197 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (505 aa)
Tlr3Toll like receptor 3. (92 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (653 aa)
LBPLipopolysaccharide binding protein. (494 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (824 aa)
ENSFDAP00000018414annotation not available (666 aa)
UbcPolyubiquitin-B. (235 aa)
GsdmeNon-syndromic hearing impairment protein 5. (123 aa)
Hmgb1High mobility group protein B1. (215 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (894 aa)
ENSFDAP00000017776annotation not available (72 aa)
IRF3Interferon regulatory factor 3. (428 aa)
Ppp2caSerine/threonine-protein phosphatase. (275 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7. (427 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (462 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
N4BP1NEDD4-binding protein 1. (825 aa)
IRF7Interferon regulatory factor 7. (430 aa)
LOC104863125Toll-like receptor 9. (1029 aa)
NFKB2Nuclear factor kappa B subunit 2. (752 aa)
PELI3Pellino E3 ubiquitin protein ligase family member 3. (445 aa)
NFKBIANF-kappa-B inhibitor alpha. (224 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
CD180CD180 antigen. (671 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1097 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (606 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1. (112 aa)
FNBP4Formin binding protein 4. (916 aa)
CTSSGolgi phosphoprotein 3-like; Belongs to the peptidase C1 family. (331 aa)
H920_02493Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
CREB5cAMP responsive element binding protein 5. (508 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
CTSKCathepsin K. (328 aa)
LOC104865813Pulmonary surfactant-associated protein A. (240 aa)
CTSVCathepsin L1; Belongs to the peptidase C1 family. (334 aa)
EEA1Early endosome antigen 1. (1427 aa)
TLR8Toll-like receptor 8; Belongs to the Toll-like receptor family. (1035 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (175 aa)
RBSNRabenosyn-5. (735 aa)
RPS6KA5Ribosomal protein S6 kinase. (810 aa)
VRK3Inactive serine/threonine-protein kinase VRK3. (453 aa)
GSDMDGasdermin-D. (477 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (585 aa)
LRRC45Leucine-rich repeat-containing protein 45. (662 aa)
USP14Ubiquitin specific peptidase 14. (440 aa)
UNC93AProtein unc-93 like protein A. (457 aa)
Dusp3Dual specificity phosphatase 3. (117 aa)
TLR5Toll-like receptor 5; Belongs to the Toll-like receptor family. (857 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
TLR1Toll-like receptor 1; Belongs to the Toll-like receptor family. (808 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
APPAmyloid beta A4 protein. (766 aa)
MAPK11Mitogen-activated protein kinase 11. (325 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (928 aa)
ENSFDAP00000010317annotation not available (274 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1347 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
ELK1ETS domain-containing protein Elk-1. (427 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (254 aa)
PELI2Protein pellino like protein 2. (351 aa)
BPIFCBactericidal/permeability-increasing protein-like 2. (507 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein. (209 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (341 aa)
SIGIRRSingle Ig and TIR domain containing. (408 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
LY86Lymphocyte antigen 86. (162 aa)
ENSFDAP00000007247annotation not available (119 aa)
KHNYNProtein KHNYN. (670 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4. (833 aa)
TIFATRAF-interacting protein with FHA domain-containing protein A. (185 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (839 aa)
ENSFDAP00000006648annotation not available (129 aa)
LRRC74BLeucine rich repeat containing 74B. (378 aa)
RELATranscription factor p65. (545 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
SARM1Sterile alpha and TIR motif-containing protein 1. (614 aa)
DUSP4Dual specificity phosphatase 4. (394 aa)
NLRP6NLR family pyrin domain containing 6. (808 aa)
ENSFDAP00000005475annotation not available (139 aa)
S100A1Protein S100; Belongs to the S-100 family. (94 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (808 aa)
APOBApolipoprotein B-100. (4381 aa)
ALPK1Alpha-protein kinase 1. (1003 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1382 aa)
NLRC5Protein NLRC5. (1784 aa)
PTPN4Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)
ENSFDAP00000004787annotation not available (192 aa)
SFTPDPulmonary surfactant-associated protein D. (375 aa)
LRRC74AUncharacterized protein. (476 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSFDAP00000004169annotation not available (234 aa)
CNPY3Protein canopy like protein 3. (273 aa)
Atf7Cyclic AMP-dependent transcription factor ATF-7. (483 aa)
LOC104865812Pulmonary surfactant-associated protein A. (248 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (892 aa)
TLR2Toll-like receptor 2. (718 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
LRRC71Leucine-rich repeat-containing protein 71. (462 aa)
UNC93B1Protein unc-93 like protein B1. (550 aa)
ENSFDAP00000002920annotation not available (87 aa)
BPIBactericidal permeability increasing protein. (483 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
HSP90B1Endoplasmin. (819 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (340 aa)
S100BProtein S100-B; Belongs to the S-100 family. (92 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (573 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (453 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (399 aa)
NLRX1NLR family member X1. (972 aa)
IkbkeInhibitor of nuclear factor kappa-B kinase subunit epsilon. (130 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
Map2k4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (381 aa)
Tmem189Transmembrane protein 189. (229 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
LRRC34Leucine-rich repeat-containing protein 34. (402 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (600 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
Map3k20Mitogen-activated protein kinase kinase kinase MLT. (671 aa)
ENSFDAP00000000261annotation not available (93 aa)
LOC104855315TIR domain-containing adapter molecule 2; Belongs to the EMP24/GP25L family. (235 aa)
ENSFDAP00000000144annotation not available (263 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
ENSFDAP00000000117annotation not available (223 aa)
TANKTRAF family member-associated NF-kappa-B activator. (425 aa)
Usp18Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (60 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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