89 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ITGAV	Integrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
	FBN1	Fibrillin-1. (2819 aa)
	PPM1A	Protein phosphatase 1A; Belongs to the PP2C family. (382 aa)
	RBL1	RB transcriptional corepressor like 1. (1042 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (560 aa)
	TGFB2	Transforming growth factor beta 2. (398 aa)
	ENSFDAP00000002920	annotation not available (87 aa)
	BAMBI	BMP and activin membrane-bound inhibitor like protein. (235 aa)
	ITGB5	Integrin subunit beta 5. (794 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (851 aa)
	Cgn	Cingulin. (916 aa)
	NCOR2	Nuclear receptor corepressor 2. (2399 aa)
	IRX4	Iroquois-class homeodomain protein IRX-4. (425 aa)
	CCNT1	Cyclin-T1; Belongs to the cyclin family. (727 aa)
	MEIS3	Meis homeobox 3. (304 aa)
	SNW1	SNW domain containing 1. (537 aa)
	F11R	Junctional adhesion molecule A. (299 aa)
	STUB1	STIP1 homology and U box-containing protein 1. (250 aa)
	SMAD3	Mothers against decapentaplegic homolog. (429 aa)
	ENSFDAP00000005475	annotation not available (139 aa)
	JUNB	Transcription factor jun-B. (257 aa)
	CCNC	Cyclin-C; Belongs to the cyclin family. (283 aa)
	CCNK	Cyclin K. (391 aa)
	SKI	Ski oncogene. (704 aa)
	SMURF2	E3 ubiquitin-protein ligase. (742 aa)
	ENSFDAP00000007247	annotation not available (119 aa)
	PARD3	Partitioning defective 3 like protein. (1270 aa)
	TGIF2	TGFB induced factor homeobox 2. (237 aa)
	Fkbp1a	Peptidylprolyl isomerase. (108 aa)
	SP1	Transcription factor Sp1. (784 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (973 aa)
	Ube2m	Ubiquitin conjugating enzyme E2 M. (147 aa)
	SMAD7	Mothers against decapentaplegic homolog. (229 aa)
	LOC104870588	NEDD8. (78 aa)
	Arhgef18	Rho guanine nucleotide exchange factor 18. (788 aa)
	IRX6	Iroquois-class homeodomain protein IRX-6. (447 aa)
	H920_10388	NEDD8. (81 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (348 aa)
	ENSFDAP00000012053	annotation not available (81 aa)
	STRAP	Serine-threonine kinase receptor-associated protein. (350 aa)
	CDK9	Cyclin dependent kinase 9. (378 aa)
	PMEPA1	Transmembrane prostate androgen-induced protein. (234 aa)
	LTBP2	Latent-transforming growth factor beta-binding protein 2. (1665 aa)
	CCNT2	Cyclin-T2; Belongs to the cyclin family. (733 aa)
	LTBP3	Latent-transforming growth factor beta-binding protein 3. (1131 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (470 aa)
	E2F5	E2F transcription factor 5. (299 aa)
	NEDD4L	E3 ubiquitin-protein ligase. (983 aa)
	MTMR4	Myotubularin-related protein 4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1194 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	PARD6A	Partitioning defective 6 like protein alpha. (347 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (758 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	ITGB8	Integrin beta; Belongs to the integrin beta chain family. (768 aa)
	E2F4	E2F transcription factor 4. (408 aa)
	ENSFDAP00000015888	annotation not available (251 aa)
	Itgb3	Integrin beta; Belongs to the integrin beta chain family. (761 aa)
	LTBP1	Latent-transforming growth factor beta-binding protein 1. (1554 aa)
	TRIM33	E3 ubiquitin-protein ligase TRIM33. (951 aa)
	ENSFDAP00000017336	annotation not available (225 aa)
	SMURF1	E3 ubiquitin-protein ligase SMURF1. (744 aa)
	MKX	Homeobox protein Mohawk. (344 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	CDK8	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
	Tfdp2	Transcription factor Dp-2. (446 aa)
	MEN1	Menin. (616 aa)
	MAPK3	Mitogen-activated protein kinase. (322 aa)
	LTBP4	Latent transforming growth factor beta binding protein 4. (1555 aa)
	ZFYVE9	Zinc finger FYVE domain-containing protein. (1399 aa)
	RNF111	E3 ubiquitin-protein ligase Arkadia; Belongs to the cyclin family. (987 aa)
	MAPK1	Mitogen-activated protein kinase. (320 aa)
	ITGA8	Integrin alpha-8; Belongs to the integrin alpha chain family. (992 aa)
	Tgif1	Homeobox protein TGIF1. (79 aa)
	HDAC1	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
	TFDP1	Transcription factor. (410 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	USP9X	Putative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2554 aa)
	TGFB1	Transforming growth factor beta-1. (333 aa)
	CCNQ	Cyclin-related protein FAM58A. (211 aa)
	ITGB6	Integrin beta; Belongs to the integrin beta chain family. (807 aa)
	NCOR1	Nuclear receptor corepressor 1. (2434 aa)
	SKIL	Ski-like protein. (679 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	FURIN	Furin; Belongs to the peptidase S8 family. (796 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (803 aa)
	RHOA	Transforming protein RhoA. (193 aa)
	PARD3B	Partitioning defective 3 like protein B. (1166 aa)
	UBE2D1	Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B4	SMAD7	ENSFDAP00000012029	ENSFDAP00000009760	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mothers against decapentaplegic homolog.	0.505
ATP1B4	SNW1	ENSFDAP00000012029	ENSFDAP00000004529	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SNW domain containing 1.	0.874
Arhgef18	Cgn	ENSFDAP00000010437	ENSFDAP00000003375	Rho guanine nucleotide exchange factor 18.	Cingulin.	0.891
Arhgef18	F11R	ENSFDAP00000010437	ENSFDAP00000004841	Rho guanine nucleotide exchange factor 18.	Junctional adhesion molecule A.	0.627
Arhgef18	PARD3	ENSFDAP00000010437	ENSFDAP00000007376	Rho guanine nucleotide exchange factor 18.	Partitioning defective 3 like protein.	0.587
Arhgef18	PARD3B	ENSFDAP00000010437	ENSFDAP00000022514	Rho guanine nucleotide exchange factor 18.	Partitioning defective 3 like protein B.	0.530
Arhgef18	RHOA	ENSFDAP00000010437	ENSFDAP00000022186	Rho guanine nucleotide exchange factor 18.	Transforming protein RhoA.	0.967
Arhgef18	RPS27A	ENSFDAP00000010437	ENSFDAP00000014104	Rho guanine nucleotide exchange factor 18.	Ubiquitin-40S ribosomal protein S27a.	0.552
Arhgef18	SMURF1	ENSFDAP00000010437	ENSFDAP00000017944	Rho guanine nucleotide exchange factor 18.	E3 ubiquitin-protein ligase SMURF1.	0.487
Arhgef18	SMURF2	ENSFDAP00000010437	ENSFDAP00000007112	Rho guanine nucleotide exchange factor 18.	E3 ubiquitin-protein ligase.	0.437
Arhgef18	TGFBR1	ENSFDAP00000010437	ENSFDAP00000013444	Rho guanine nucleotide exchange factor 18.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.495
Arhgef18	TGFBR2	ENSFDAP00000010437	ENSFDAP00000002775	Rho guanine nucleotide exchange factor 18.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.509
Arhgef18	Ubc	ENSFDAP00000010437	ENSFDAP00000018389	Rho guanine nucleotide exchange factor 18.	Polyubiquitin-B.	0.572
BAMBI	SMAD2	ENSFDAP00000003222	ENSFDAP00000015181	BMP and activin membrane-bound inhibitor like protein.	Mothers against decapentaplegic homolog.	0.624
BAMBI	SMAD3	ENSFDAP00000003222	ENSFDAP00000005300	BMP and activin membrane-bound inhibitor like protein.	Mothers against decapentaplegic homolog.	0.623
BAMBI	SMAD4	ENSFDAP00000003222	ENSFDAP00000020857	BMP and activin membrane-bound inhibitor like protein.	Mothers against decapentaplegic homolog.	0.699
BAMBI	SMAD7	ENSFDAP00000003222	ENSFDAP00000009760	BMP and activin membrane-bound inhibitor like protein.	Mothers against decapentaplegic homolog.	0.910
BAMBI	TGFB1	ENSFDAP00000003222	ENSFDAP00000020924	BMP and activin membrane-bound inhibitor like protein.	Transforming growth factor beta-1.	0.750
BAMBI	TGFB2	ENSFDAP00000003222	ENSFDAP00000002834	BMP and activin membrane-bound inhibitor like protein.	Transforming growth factor beta 2.	0.420
BAMBI	TGFBR1	ENSFDAP00000003222	ENSFDAP00000013444	BMP and activin membrane-bound inhibitor like protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.953