87 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (185 aa)
	CES3	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (671 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (396 aa)
	PLTP	Phospholipid transfer protein. (494 aa)
	ALB	Serum albumin. (607 aa)
	FURIN	Furin; Belongs to the peptidase S8 family. (796 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	PLEKHD1	UPF0639 protein. (506 aa)
	ZDHHC8	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (727 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (928 aa)
	APOE	Apolipoprotein E. (228 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
	PLG	Plasminogen. (837 aa)
	LIPG	Endothelial lipase. (500 aa)
	LMF1	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (583 aa)
	SOAT1	Sterol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (544 aa)
	CLTCL1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1263 aa)
	H920_04941	Apolipoprotein C-IV. (97 aa)
	PTCHD4	SSD domain-containing protein. (810 aa)
	AADACL3	Arylacetamide deacetylase-like 3. (385 aa)
	APOA2	Apolipoprotein A-II. (101 aa)
	APOA4	Apolipoprotein A-IV. (399 aa)
	PDIA2	Protein disulfide-isomerase A2. (529 aa)
	Apoc1	Apolipoprotein C-I. (68 aa)
	NR1H2	Oxysterols receptor LXR-beta. (368 aa)
	GPIHBP1	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1. (196 aa)
	LIPC	Hepatic triacylglycerol lipase. (455 aa)
	A2M	Alpha-2-macroglobulin. (1475 aa)
	APOA1	Apolipoprotein A1. (264 aa)
	AP2M1	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (435 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	NPC1	Niemann-Pick C1 protein. (1258 aa)
	MTTP	Microsomal triglyceride transfer protein large subunit. (894 aa)
	ENSFDAP00000016887	annotation not available (781 aa)
	NPC2	Epididymal secretory protein E1. (149 aa)
	CUBN	Cubilin. (3618 aa)
	LSR	Lipolysis-stimulated lipoprotein receptor. (597 aa)
	LDLR	Low-density lipoprotein receptor. (779 aa)
	APOF	Apolipoprotein F. (317 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (758 aa)
	ABCG1	ATP-binding cassette sub-family G member 1. (618 aa)
	Ap2b1	AP complex subunit beta. (951 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	CDCP2	CUB domain-containing protein 2. (534 aa)
	HDLBP	Vigilin. (1265 aa)
	Apobr	Apolipoprotein B receptor. (896 aa)
	ILDR2	Immunoglobulin like domain containing receptor 2. (408 aa)
	SMPDL3A	Acid sphingomyelinase-like phosphodiesterase 3a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (408 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	ANGPTL3	Angiopoietin-related protein 3. (460 aa)
	PCSK6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (870 aa)
	APOA5	Apolipoprotein A-V. (367 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (502 aa)
	Apoc3	Apolipoprotein C-III. (147 aa)
	LCAT	Lecithin-cholesterol acyltransferase. (438 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha. (343 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
	LMF2	Lipase maturation factor 2. (669 aa)
	APOB	Apolipoprotein B-100. (4381 aa)
	ANGPTL8	Angiopoietin like 8. (198 aa)
	LOC104864926	Arylacetamide deacetylase-like 4. (407 aa)
	H920_07005	Arylacetamide deacetylase-like 4. (341 aa)
	MYLIP	E3 ubiquitin-protein ligase MYLIP. (416 aa)
	NR1H3	Oxysterols receptor LXR-alpha. (443 aa)
	AP2A1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (976 aa)
	CLHC1	TSNAXIP1_N domain-containing protein. (591 aa)
	ABCA1	ATP-binding cassette sub-family A member 1. (2119 aa)
	APOC2	Apolipoprotein C-II. (101 aa)
	P4HB	Protein disulfide-isomerase. (509 aa)
	PTCHD3	Patched domain-containing protein 3. (884 aa)
	BMP1	Metalloendopeptidase. (935 aa)
	PCSK5	Proprotein convertase subtilisin/kexin type 5. (1852 aa)
	LOC104864922	Arylacetamide deacetylase-like 4. (339 aa)
	NCEH1	Neutral cholesterol ester hydrolase 1. (408 aa)
	LDLRAP1	Low density lipoprotein receptor adapter protein 1. (278 aa)
	VLDLR	Very low density lipoprotein receptor. (845 aa)
	PTCHD1	Patched domain containing 1. (869 aa)
	SAR1A	GTP-binding protein SAR1a; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	SAR1B	GTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (567 aa)
	LOC104850728	Ovostatin like protein 2. (1454 aa)
	ANGPTL4	Angiopoietin-related protein 4. (300 aa)
	SOAT2	Sterol O-acyltransferase 2; Belongs to the membrane-bound acyltransferase family. (532 aa)
	LOC104850731	Alpha-1-inhibitor 3-like. (1381 aa)
	LIPA	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
	ZDHHC19	Zinc finger DHHC-type containing 19. (330 aa)
	ENSFDAP00000002920	annotation not available (87 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A2M	ALB	ENSFDAP00000018621	ENSFDAP00000022873	Alpha-2-macroglobulin.	Serum albumin.	0.492
A2M	APOE	ENSFDAP00000018621	ENSFDAP00000021206	Alpha-2-macroglobulin.	Apolipoprotein E.	0.470
A2M	PLG	ENSFDAP00000018621	ENSFDAP00000020863	Alpha-2-macroglobulin.	Plasminogen.	0.618
ABCA1	APOA1	ENSFDAP00000007781	ENSFDAP00000018576	ATP-binding cassette sub-family A member 1.	Apolipoprotein A1.	0.909
ABCA1	APOA2	ENSFDAP00000007781	ENSFDAP00000019181	ATP-binding cassette sub-family A member 1.	Apolipoprotein A-II.	0.576
ABCA1	APOB	ENSFDAP00000007781	ENSFDAP00000005130	ATP-binding cassette sub-family A member 1.	Apolipoprotein B-100.	0.540
ABCA1	APOE	ENSFDAP00000007781	ENSFDAP00000021206	ATP-binding cassette sub-family A member 1.	Apolipoprotein E.	0.634
ABCA1	LCAT	ENSFDAP00000007781	ENSFDAP00000003179	ATP-binding cassette sub-family A member 1.	Lecithin-cholesterol acyltransferase.	0.558
ABCA1	LIPC	ENSFDAP00000007781	ENSFDAP00000018624	ATP-binding cassette sub-family A member 1.	Hepatic triacylglycerol lipase.	0.421
ABCA1	MYLIP	ENSFDAP00000007781	ENSFDAP00000006236	ATP-binding cassette sub-family A member 1.	E3 ubiquitin-protein ligase MYLIP.	0.468
ABCA1	NPC1	ENSFDAP00000007781	ENSFDAP00000018244	ATP-binding cassette sub-family A member 1.	Niemann-Pick C1 protein.	0.462
ABCA1	NR1H2	ENSFDAP00000007781	ENSFDAP00000018789	ATP-binding cassette sub-family A member 1.	Oxysterols receptor LXR-beta.	0.901
ABCA1	NR1H3	ENSFDAP00000007781	ENSFDAP00000006253	ATP-binding cassette sub-family A member 1.	Oxysterols receptor LXR-alpha.	0.868
ABCA1	PLTP	ENSFDAP00000007781	ENSFDAP00000022944	ATP-binding cassette sub-family A member 1.	Phospholipid transfer protein.	0.441
ABCA1	PRKACA	ENSFDAP00000007781	ENSFDAP00000003727	ATP-binding cassette sub-family A member 1.	Protein kinase cAMP-activated catalytic subunit alpha.	0.567
ABCA1	PRKACB	ENSFDAP00000007781	ENSFDAP00000023184	ATP-binding cassette sub-family A member 1.	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.	0.572
ABCA1	SCARB1	ENSFDAP00000007781	ENSFDAP00000003094	ATP-binding cassette sub-family A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.569
ABCG1	APOA1	ENSFDAP00000014886	ENSFDAP00000018576	ATP-binding cassette sub-family G member 1.	Apolipoprotein A1.	0.425
ABCG1	APOA2	ENSFDAP00000014886	ENSFDAP00000019181	ATP-binding cassette sub-family G member 1.	Apolipoprotein A-II.	0.424
ABCG1	APOE	ENSFDAP00000014886	ENSFDAP00000021206	ATP-binding cassette sub-family G member 1.	Apolipoprotein E.	0.568