STRINGSTRING
PTPRM PTPRM ARHGEF7 ARHGEF7 EGF EGF PTPN11 PTPN11 STAM STAM SPRY1 SPRY1 ENSFDAP00000002920 ENSFDAP00000002920 BTC BTC PXN PXN CBL CBL EGFR EGFR PTPRK PTPRK AAMP AAMP SH3GL2 SH3GL2 GRB2 GRB2 LPXN LPXN HGS HGS SOS1 SOS1 GAB1 GAB1 SH3GL1 SH3GL1 ENSFDAP00000008900 ENSFDAP00000008900 FNDC3B FNDC3B SPRY2 SPRY2 AREG AREG SH3GL3 SH3GL3 HBEGF HBEGF PAG1 PAG1 Sh3kbp1 Sh3kbp1 PTPRT PTPRT H920_14239 H920_14239 SPRY3 SPRY3 HRAS HRAS PTPN3 PTPN3 EREG EREG CSK CSK KRAS KRAS RPS27A RPS27A LRIG2 LRIG2 STAM2 STAM2 Cdc42 Cdc42 ENSFDAP00000016516 ENSFDAP00000016516 TGFA TGFA EPS15 EPS15 Ubc Ubc PIK3CA PIK3CA LRIG3 LRIG3 PLCG1 PLCG1 FNDC3A FNDC3A LRIG1 LRIG1 EPGN EPGN SHC1 SHC1 PIK3R1 PIK3R1 CSDE1 CSDE1 UBA52 UBA52 EPS15L1 EPS15L1 NRAS NRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPRMReceptor-type tyrosine-protein phosphatase mu. (1457 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (809 aa)
EGFPro-epidermal growth factor. (1155 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (600 aa)
STAMSignal transducing adapter molecule 1. (542 aa)
SPRY1Protein sprouty like protein 1. (319 aa)
ENSFDAP00000002920annotation not available (87 aa)
BTCProbetacellulin. (179 aa)
PXNPaxillin. (585 aa)
CBLE3 ubiquitin-protein ligase CBL. (851 aa)
EGFRReceptor protein-tyrosine kinase. (1168 aa)
PTPRKReceptor-type tyrosine-protein phosphatase kappa. (1441 aa)
AAMPAngio-associated migratory cell protein. (436 aa)
SH3GL2Endophilin-A1. (349 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
LPXNLeupaxin. (380 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate. (778 aa)
SOS1Son of sevenless like protein 1. (1289 aa)
GAB1GRB2-associated-binding protein 1. (698 aa)
SH3GL1Endophilin-A2. (340 aa)
ENSFDAP00000008900annotation not available (172 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
SPRY2Protein sprouty like protein 2. (315 aa)
AREGAmphiregulin. (242 aa)
SH3GL3Endophilin-A3. (312 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (434 aa)
Sh3kbp1SH3 domain containing kinase binding protein 1. (709 aa)
PTPRTReceptor-type tyrosine-protein phosphatase T. (1435 aa)
H920_14239SH3 domain-containing kinase-binding protein 1. (113 aa)
SPRY3Protein sprouty like protein 3. (288 aa)
HRASHRas proto-oncogene, GTPase. (191 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (940 aa)
EREGProepiregulin. (163 aa)
CSKC-terminal Src kinase. (450 aa)
KRASGTPase HRas. (189 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1061 aa)
STAM2Signal transducing adapter molecule 2. (524 aa)
Cdc42Cell division control protein 42 like protein. (191 aa)
ENSFDAP00000016516annotation not available (156 aa)
TGFAProtransforming growth factor alpha. (157 aa)
EPS15Epidermal growth factor receptor substrate 15. (926 aa)
UbcPolyubiquitin-B. (235 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1050 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1198 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1007 aa)
EPGNEpithelial mitogen. (152 aa)
SHC1SHC-transforming protein 1. (583 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
CSDE1Cold shock domain-containing protein E1. (798 aa)
UBA52KxDL motif containing 1. (232 aa)
EPS15L1Epidermal growth factor receptor substrate 15-like 1. (795 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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