STRINGSTRING
KLB KLB Fgf2 Fgf2 NCBP2 NCBP2 ENSFDAP00000000144 ENSFDAP00000000144 Polr2j Polr2j PTPN11 PTPN11 NCBP1 NCBP1 SPRED1 SPRED1 BRAF BRAF FGF16 FGF16 POLR2I POLR2I FGF17 FGF17 Ppp2r1a Ppp2r1a FGF9 FGF9 GALNT3 GALNT3 ENSFDAP00000002920 ENSFDAP00000002920 CBL CBL ESRP2 ESRP2 STIL STIL Fgf4 Fgf4 GRB2 GRB2 FRS3 FRS3 TIA1 TIA1 LOC104874687 LOC104874687 POLR2E POLR2E FGF20 FGF20 HNRNPM HNRNPM ESRP1 ESRP1 SOS1 SOS1 GAB1 GAB1 SPRED2 SPRED2 GTF2F1 GTF2F1 FGF6 FGF6 PTBP3 PTBP3 ENSFDAP00000009348 ENSFDAP00000009348 FGF10 FGF10 FNDC3B FNDC3B SPRY2 SPRY2 POLR2G POLR2G GTF2F2 GTF2F2 FGFR2 FGFR2 PTBP1 PTBP1 PPP2CB PPP2CB ENSFDAP00000011192 ENSFDAP00000011192 FGF18 FGF18 FLRT3 FLRT3 SPRY3 SPRY3 HRAS HRAS FGF7 FGF7 FGFRL1 FGFRL1 FGF5 FGF5 KRAS KRAS PTBP2 PTBP2 POLR2K POLR2K Mknk1 Mknk1 RPS27A RPS27A H920_10163 H920_10163 H920_02493 H920_02493 FLRT2 FLRT2 FGFR1 FGFR1 Fgf22 Fgf22 TIAL1 TIAL1 ANOS1 ANOS1 Fgf23 Fgf23 Ppp2ca Ppp2ca POLR2B POLR2B RBFOX2 RBFOX2 KL KL FGF1 FGF1 ENSFDAP00000017806 ENSFDAP00000017806 Frs2 Frs2 POLR2F POLR2F FGFR3 FGFR3 Ubc Ubc FGF8 FGF8 Flrt1 Flrt1 MKNK2 MKNK2 H920_17037 H920_17037 MAPK3 MAPK3 POLR2H POLR2H PIK3CA PIK3CA MAPK1 MAPK1 POLR2C POLR2C PLCG1 PLCG1 FNDC3A FNDC3A Polr2a Polr2a SHC1 SHC1 PIK3R1 PIK3R1 CSDE1 CSDE1 UBA52 UBA52 POLR2D POLR2D POLR2L POLR2L NRAS NRAS FGFR4 FGFR4 Hnrnpa1 Hnrnpa1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KLBBeta-klotho. (1016 aa)
Fgf2Fibroblast growth factor 2. (129 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
ENSFDAP00000000144annotation not available (263 aa)
Polr2jDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (600 aa)
NCBP1Nuclear cap-binding protein subunit 1. (790 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1. (422 aa)
BRAFSerine/threonine-protein kinase B-raf. (740 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (573 aa)
FGF9Fibroblast growth factor 9. (208 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
ENSFDAP00000002920annotation not available (87 aa)
CBLE3 ubiquitin-protein ligase CBL. (851 aa)
ESRP2Epithelial splicing regulatory protein 2. (694 aa)
STILRRM domain-containing protein. (1274 aa)
Fgf4Fibroblast growth factor 4. (52 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
FRS3Fibroblast growth factor receptor substrate 3. (486 aa)
TIA1Nucleolysin TIA-1 isoform p40. (386 aa)
LOC104874687Fibroblast growth factor-binding protein 1. (249 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
FGF20Fibroblast growth factor 20. (184 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (726 aa)
ESRP1Epithelial splicing regulatory protein 1. (634 aa)
SOS1Son of sevenless like protein 1. (1289 aa)
GAB1GRB2-associated-binding protein 1. (698 aa)
SPRED2Sprouty-related, EVH1 domain-containing protein 2. (413 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (512 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa)
PTBP3Regulator of differentiation 1. (552 aa)
ENSFDAP00000009348annotation not available (427 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
SPRY2Protein sprouty like protein 2. (315 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
GTF2F2Short-chain dehydrogenase/reductase family 42E member 1. (249 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
PTBP1Polypyrimidine tract-binding protein 1. (557 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
ENSFDAP00000011192annotation not available (51 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3. (648 aa)
SPRY3Protein sprouty like protein 3. (288 aa)
HRASHRas proto-oncogene, GTPase. (191 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGFRL1Fibroblast growth factor receptor-like 1. (476 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (315 aa)
KRASGTPase HRas. (189 aa)
PTBP2Polypyrimidine tract-binding protein 2. (532 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
Mknk1MAP kinase-interacting serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (415 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
H920_10163Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (137 aa)
H920_02493Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
FLRT2Leucine-rich repeat transmembrane protein FLRT2. (660 aa)
FGFR1Basic fibroblast growth factor receptor 1. (820 aa)
Fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (95 aa)
TIAL1Nucleolysin TIAR. (385 aa)
ANOS1Anosmin-1. (646 aa)
Fgf23Fibroblast growth factor 23. (129 aa)
Ppp2caSerine/threonine-protein phosphatase. (275 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1178 aa)
RBFOX2RNA binding protein fox-1 like protein 2. (328 aa)
KLKlotho. (969 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ENSFDAP00000017806annotation not available (118 aa)
Frs2Fibroblast growth factor receptor substrate 2. (508 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
FGFR3Fibroblast growth factor receptor 3. (748 aa)
UbcPolyubiquitin-B. (235 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
Flrt1Leucine-rich repeat transmembrane protein FLRT1. (674 aa)
MKNK2MAP kinase-interacting serine/threonine-protein kinase 2. (459 aa)
H920_17037Heterogeneous nuclear ribonucleoprotein A1. (268 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
POLR2HRNA polymerase II subunit H. (150 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3. (266 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1198 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
SHC1SHC-transforming protein 1. (583 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
CSDE1Cold shock domain-containing protein E1. (798 aa)
UBA52KxDL motif containing 1. (232 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
Hnrnpa1Heterogeneous nuclear ribonucleoprotein A1. (373 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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