STRINGSTRING
Itgb3 Itgb3 PTPN6 PTPN6 INPP5D INPP5D FYN FYN FNDC3B FNDC3B YES1 YES1 PECAM1 PECAM1 LYN LYN ITGAV ITGAV SRC SRC PTPN11 PTPN11 FNDC3A FNDC3A PLCG1 PLCG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Itgb3Integrin beta; Belongs to the integrin beta chain family. (761 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
INPP5DPhosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1. (1140 aa)
FYNTyrosine-protein kinase. (537 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
YES1Tyrosine-protein kinase. (541 aa)
PECAM1Platelet endothelial cell adhesion molecule. (740 aa)
LYNTyrosine-protein kinase. (512 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
SRCSRC proto-oncogene, non-receptor tyrosine kinase. (476 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (600 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1198 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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