40 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	Fkbp1a	Peptidylprolyl isomerase. (108 aa)
	Ube2m	Ubiquitin conjugating enzyme E2 M. (147 aa)
	ITGAV	Integrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
	SMAD7	Mothers against decapentaplegic homolog. (229 aa)
	LOC104870588	NEDD8. (78 aa)
	FBN1	Fibrillin-1. (2819 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (560 aa)
	TGFB2	Transforming growth factor beta 2. (398 aa)
	ENSFDAP00000002920	annotation not available (87 aa)
	BAMBI	BMP and activin membrane-bound inhibitor like protein. (235 aa)
	STUB1	STIP1 homology and U box-containing protein 1. (250 aa)
	SMAD3	Mothers against decapentaplegic homolog. (429 aa)
	SMURF2	E3 ubiquitin-protein ligase. (742 aa)
	ITGB5	Integrin subunit beta 5. (794 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (851 aa)
	ITGB8	Integrin beta; Belongs to the integrin beta chain family. (768 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (758 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	MTMR4	Myotubularin-related protein 4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1194 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (470 aa)
	STRAP	Serine-threonine kinase receptor-associated protein. (350 aa)
	ENSFDAP00000012053	annotation not available (81 aa)
	H920_10388	NEDD8. (81 aa)
	LTBP3	Latent-transforming growth factor beta-binding protein 3. (1131 aa)
	LTBP2	Latent-transforming growth factor beta-binding protein 2. (1665 aa)
	PMEPA1	Transmembrane prostate androgen-induced protein. (234 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (803 aa)
	FURIN	Furin; Belongs to the peptidase S8 family. (796 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	ITGB6	Integrin beta; Belongs to the integrin beta chain family. (807 aa)
	TGFB1	Transforming growth factor beta-1. (333 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	ITGA8	Integrin alpha-8; Belongs to the integrin alpha chain family. (992 aa)
	ZFYVE9	Zinc finger FYVE domain-containing protein. (1399 aa)
	LTBP4	Latent transforming growth factor beta binding protein 4. (1555 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	LTBP1	Latent-transforming growth factor beta-binding protein 1. (1554 aa)
	Itgb3	Integrin beta; Belongs to the integrin beta chain family. (761 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAMBI	SMAD2	ENSFDAP00000003222	ENSFDAP00000015181	BMP and activin membrane-bound inhibitor like protein.	Mothers against decapentaplegic homolog.	0.624
BAMBI	SMAD3	ENSFDAP00000003222	ENSFDAP00000005300	BMP and activin membrane-bound inhibitor like protein.	Mothers against decapentaplegic homolog.	0.623
BAMBI	SMAD4	ENSFDAP00000003222	ENSFDAP00000020857	BMP and activin membrane-bound inhibitor like protein.	Mothers against decapentaplegic homolog.	0.699
BAMBI	SMAD7	ENSFDAP00000003222	ENSFDAP00000009760	BMP and activin membrane-bound inhibitor like protein.	Mothers against decapentaplegic homolog.	0.910
BAMBI	TGFB1	ENSFDAP00000003222	ENSFDAP00000020924	BMP and activin membrane-bound inhibitor like protein.	Transforming growth factor beta-1.	0.750
BAMBI	TGFB2	ENSFDAP00000003222	ENSFDAP00000002834	BMP and activin membrane-bound inhibitor like protein.	Transforming growth factor beta 2.	0.420
BAMBI	TGFBR1	ENSFDAP00000003222	ENSFDAP00000013444	BMP and activin membrane-bound inhibitor like protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.953
BAMBI	TGFBR2	ENSFDAP00000003222	ENSFDAP00000002775	BMP and activin membrane-bound inhibitor like protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.691
CBL	ENSFDAP00000002920	ENSFDAP00000003307	ENSFDAP00000002920	E3 ubiquitin-protein ligase CBL.	annotation not available	0.900
CBL	ENSFDAP00000012053	ENSFDAP00000003307	ENSFDAP00000012053	E3 ubiquitin-protein ligase CBL.	annotation not available	0.708
CBL	H920_10388	ENSFDAP00000003307	ENSFDAP00000011513	E3 ubiquitin-protein ligase CBL.	NEDD8.	0.708
CBL	LOC104870588	ENSFDAP00000003307	ENSFDAP00000009973	E3 ubiquitin-protein ligase CBL.	NEDD8.	0.708
CBL	RPS27A	ENSFDAP00000003307	ENSFDAP00000014104	E3 ubiquitin-protein ligase CBL.	Ubiquitin-40S ribosomal protein S27a.	0.964
CBL	SMURF2	ENSFDAP00000003307	ENSFDAP00000007112	E3 ubiquitin-protein ligase CBL.	E3 ubiquitin-protein ligase.	0.939
CBL	TGFBR1	ENSFDAP00000003307	ENSFDAP00000013444	E3 ubiquitin-protein ligase CBL.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.544
CBL	TGFBR2	ENSFDAP00000003307	ENSFDAP00000002775	E3 ubiquitin-protein ligase CBL.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.875
CBL	UBA52	ENSFDAP00000003307	ENSFDAP00000022032	E3 ubiquitin-protein ligase CBL.	KxDL motif containing 1.	0.957
CBL	Ubc	ENSFDAP00000003307	ENSFDAP00000018389	E3 ubiquitin-protein ligase CBL.	Polyubiquitin-B.	0.970
CBL	Ube2m	ENSFDAP00000003307	ENSFDAP00000009744	E3 ubiquitin-protein ligase CBL.	Ubiquitin conjugating enzyme E2 M.	0.730
ENSFDAP00000002920	CBL	ENSFDAP00000002920	ENSFDAP00000003307	annotation not available	E3 ubiquitin-protein ligase CBL.	0.900