52 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCNK	Cyclin K. (391 aa)
	PPM1A	Protein phosphatase 1A; Belongs to the PP2C family. (382 aa)
	RBL1	RB transcriptional corepressor like 1. (1042 aa)
	ENSFDAP00000002920	annotation not available (87 aa)
	NCOR2	Nuclear receptor corepressor 2. (2399 aa)
	IRX4	Iroquois-class homeodomain protein IRX-4. (425 aa)
	CCNT1	Cyclin-T1; Belongs to the cyclin family. (727 aa)
	UBE2D1	Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
	FURIN	Furin; Belongs to the peptidase S8 family. (796 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	SKIL	Ski-like protein. (679 aa)
	NCOR1	Nuclear receptor corepressor 1. (2434 aa)
	CCNQ	Cyclin-related protein FAM58A. (211 aa)
	USP9X	Putative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2554 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	TFDP1	Transcription factor. (410 aa)
	HDAC1	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
	Tgif1	Homeobox protein TGIF1. (79 aa)
	MAPK1	Mitogen-activated protein kinase. (320 aa)
	RNF111	E3 ubiquitin-protein ligase Arkadia; Belongs to the cyclin family. (987 aa)
	MAPK3	Mitogen-activated protein kinase. (322 aa)
	MEN1	Menin. (616 aa)
	Tfdp2	Transcription factor Dp-2. (446 aa)
	CDK8	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	MKX	Homeobox protein Mohawk. (344 aa)
	ENSFDAP00000017336	annotation not available (225 aa)
	TRIM33	E3 ubiquitin-protein ligase TRIM33. (951 aa)
	ENSFDAP00000015888	annotation not available (251 aa)
	E2F4	E2F transcription factor 4. (408 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (758 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	NEDD4L	E3 ubiquitin-protein ligase. (983 aa)
	E2F5	E2F transcription factor 5. (299 aa)
	CCNT2	Cyclin-T2; Belongs to the cyclin family. (733 aa)
	CDK9	Cyclin dependent kinase 9. (378 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (348 aa)
	IRX6	Iroquois-class homeodomain protein IRX-6. (447 aa)
	SMAD7	Mothers against decapentaplegic homolog. (229 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (973 aa)
	SP1	Transcription factor Sp1. (784 aa)
	TGIF2	TGFB induced factor homeobox 2. (237 aa)
	ENSFDAP00000007247	annotation not available (119 aa)
	SMURF2	E3 ubiquitin-protein ligase. (742 aa)
	SKI	Ski oncogene. (704 aa)
	CCNC	Cyclin-C; Belongs to the cyclin family. (283 aa)
	JUNB	Transcription factor jun-B. (257 aa)
	ENSFDAP00000005475	annotation not available (139 aa)
	SMAD3	Mothers against decapentaplegic homolog. (429 aa)
	SNW1	SNW domain containing 1. (537 aa)
	MEIS3	Meis homeobox 3. (304 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B4	SMAD7	ENSFDAP00000012029	ENSFDAP00000009760	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mothers against decapentaplegic homolog.	0.505
ATP1B4	SNW1	ENSFDAP00000012029	ENSFDAP00000004529	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SNW domain containing 1.	0.874
CCNC	CCNK	ENSFDAP00000006187	ENSFDAP00000006241	Cyclin-C; Belongs to the cyclin family.	Cyclin K.	0.853
CCNC	CCNQ	ENSFDAP00000006187	ENSFDAP00000020936	Cyclin-C; Belongs to the cyclin family.	Cyclin-related protein FAM58A.	0.702
CCNC	CCNT1	ENSFDAP00000006187	ENSFDAP00000003675	Cyclin-C; Belongs to the cyclin family.	Cyclin-T1; Belongs to the cyclin family.	0.740
CCNC	CCNT2	ENSFDAP00000006187	ENSFDAP00000013397	Cyclin-C; Belongs to the cyclin family.	Cyclin-T2; Belongs to the cyclin family.	0.740
CCNC	CDK8	ENSFDAP00000006187	ENSFDAP00000018478	Cyclin-C; Belongs to the cyclin family.	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily.	0.999
CCNC	CDK9	ENSFDAP00000006187	ENSFDAP00000012951	Cyclin-C; Belongs to the cyclin family.	Cyclin dependent kinase 9.	0.852
CCNC	SMAD2	ENSFDAP00000006187	ENSFDAP00000015181	Cyclin-C; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.445
CCNC	SMAD3	ENSFDAP00000006187	ENSFDAP00000005300	Cyclin-C; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.445
CCNC	SMAD4	ENSFDAP00000006187	ENSFDAP00000020857	Cyclin-C; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.646
CCNC	SMAD7	ENSFDAP00000006187	ENSFDAP00000009760	Cyclin-C; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.425
CCNK	CCNC	ENSFDAP00000006241	ENSFDAP00000006187	Cyclin K.	Cyclin-C; Belongs to the cyclin family.	0.853
CCNK	CCNT1	ENSFDAP00000006241	ENSFDAP00000003675	Cyclin K.	Cyclin-T1; Belongs to the cyclin family.	0.822
CCNK	CCNT2	ENSFDAP00000006241	ENSFDAP00000013397	Cyclin K.	Cyclin-T2; Belongs to the cyclin family.	0.828
CCNK	CDK8	ENSFDAP00000006241	ENSFDAP00000018478	Cyclin K.	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily.	0.810
CCNK	CDK9	ENSFDAP00000006241	ENSFDAP00000012951	Cyclin K.	Cyclin dependent kinase 9.	0.986
CCNK	SMAD2	ENSFDAP00000006241	ENSFDAP00000015181	Cyclin K.	Mothers against decapentaplegic homolog.	0.484
CCNK	SMAD3	ENSFDAP00000006241	ENSFDAP00000005300	Cyclin K.	Mothers against decapentaplegic homolog.	0.484
CCNK	SMAD4	ENSFDAP00000006241	ENSFDAP00000020857	Cyclin K.	Mothers against decapentaplegic homolog.	0.689