Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATM | COP1 | ENSFDAP00000012956 | ENSFDAP00000010579 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | E3 ubiquitin-protein ligase RFWD2. | 0.837 |
| ATM | PSMD14 | ENSFDAP00000012956 | ENSFDAP00000013708 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 26S proteasome non-ATPase regulatory subunit 14. | 0.530 |
| ATM | PSMD7 | ENSFDAP00000012956 | ENSFDAP00000003749 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 26S proteasome non-ATPase regulatory subunit 7. | 0.429 |
| ATM | TP53 | ENSFDAP00000012956 | ENSFDAP00000011613 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.997 |
| ATM | Ubc | ENSFDAP00000012956 | ENSFDAP00000018389 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Polyubiquitin-B. | 0.723 |
| COP1 | ATM | ENSFDAP00000010579 | ENSFDAP00000012956 | E3 ubiquitin-protein ligase RFWD2. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.837 |
| COP1 | ENSFDAP00000002920 | ENSFDAP00000010579 | ENSFDAP00000002920 | E3 ubiquitin-protein ligase RFWD2. | annotation not available | 0.696 |
| COP1 | PSMC1 | ENSFDAP00000010579 | ENSFDAP00000020286 | E3 ubiquitin-protein ligase RFWD2. | 26S protease regulatory subunit 4; Belongs to the AAA ATPase family. | 0.586 |
| COP1 | PSMC2 | ENSFDAP00000010579 | ENSFDAP00000023077 | E3 ubiquitin-protein ligase RFWD2. | 26S protease regulatory subunit 7; Belongs to the AAA ATPase family. | 0.586 |
| COP1 | PSMC5 | ENSFDAP00000010579 | ENSFDAP00000012290 | E3 ubiquitin-protein ligase RFWD2. | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 0.586 |
| COP1 | PSMD10 | ENSFDAP00000010579 | ENSFDAP00000004516 | E3 ubiquitin-protein ligase RFWD2. | 26S proteasome non-ATPase regulatory subunit 10. | 0.603 |
| COP1 | PSMD14 | ENSFDAP00000010579 | ENSFDAP00000013708 | E3 ubiquitin-protein ligase RFWD2. | 26S proteasome non-ATPase regulatory subunit 14. | 0.579 |
| COP1 | PSMD4 | ENSFDAP00000010579 | ENSFDAP00000005658 | E3 ubiquitin-protein ligase RFWD2. | 26S proteasome non-ATPase regulatory subunit 4. | 0.549 |
| COP1 | PSMD7 | ENSFDAP00000010579 | ENSFDAP00000003749 | E3 ubiquitin-protein ligase RFWD2. | 26S proteasome non-ATPase regulatory subunit 7. | 0.575 |
| COP1 | PSME4 | ENSFDAP00000010579 | ENSFDAP00000009450 | E3 ubiquitin-protein ligase RFWD2. | Proteasome activator subunit 4. | 0.587 |
| COP1 | RPS27A | ENSFDAP00000010579 | ENSFDAP00000014104 | E3 ubiquitin-protein ligase RFWD2. | Ubiquitin-40S ribosomal protein S27a. | 0.771 |
| COP1 | TP53 | ENSFDAP00000010579 | ENSFDAP00000011613 | E3 ubiquitin-protein ligase RFWD2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.928 |
| COP1 | UBA52 | ENSFDAP00000010579 | ENSFDAP00000022032 | E3 ubiquitin-protein ligase RFWD2. | KxDL motif containing 1. | 0.696 |
| COP1 | Ubc | ENSFDAP00000010579 | ENSFDAP00000018389 | E3 ubiquitin-protein ligase RFWD2. | Polyubiquitin-B. | 0.744 |
| ENSFDAP00000002920 | COP1 | ENSFDAP00000002920 | ENSFDAP00000010579 | annotation not available | E3 ubiquitin-protein ligase RFWD2. | 0.696 |
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