STRINGSTRING
LOC104864168 LOC104864168 ENSFDAP00000006648 ENSFDAP00000006648 MAP3K3 MAP3K3 Usp18 Usp18 ENSFDAP00000000117 ENSFDAP00000000117 MAP3K2 MAP3K2 Map3k20 Map3k20 TAB1 TAB1 BTRC BTRC LRRC34 LRRC34 TRAF2 TRAF2 NKIRAS2 NKIRAS2 TAB2 TAB2 IL36RN IL36RN NLRX1 NLRX1 IL13 IL13 PELI1 PELI1 IL1RN IL1RN IRAK1 IRAK1 IL36A IL36A TOLLIP TOLLIP Il18 Il18 S100B S100B IKBKB IKBKB Irak4 Irak4 ENSFDAP00000002920 ENSFDAP00000002920 MFSD1 MFSD1 LRRC71 LRRC71 IL1RAP IL1RAP LOC104874823 LOC104874823 MAPK8 MAPK8 LRRC74A LRRC74A NLRC5 NLRC5 ALPK1 ALPK1 IL33 IL33 NLRP6 NLRP6 IRAK3 IRAK3 RELA RELA IL1R2 IL1R2 LRRC74B LRRC74B UBE2V1 UBE2V1 PTPN14 PTPN14 PTPN23 PTPN23 RPS27A RPS27A NKIRAS1 NKIRAS1 MAP3K7 MAP3K7 TRAF6 TRAF6 IL1RL2 IL1RL2 H920_20354 H920_20354 IL1R1 IL1R1 NFKBIA NFKBIA PELI3 PELI3 NFKB2 NFKB2 IL1RAPL1 IL1RAPL1 N4BP1 N4BP1 Chuk Chuk CASP8 CASP8 LOC104874822 LOC104874822 STAT3 STAT3 SQSTM1 SQSTM1 ENSFDAP00000017776 ENSFDAP00000017776 NFKB1 NFKB1 TBK1 TBK1 Hmgb1 Hmgb1 H920_15675 H920_15675 Il1b Il1b H920_01229 H920_01229 Ubc Ubc ENSFDAP00000018414 ENSFDAP00000018414 IL1F10 IL1F10 H920_06373 H920_06373 IL36G IL36G NFKBIB NFKBIB LRRC14 LRRC14 H920_16633 H920_16633 CUL1 CUL1 PTPN20 PTPN20 IKBKG IKBKG AGER AGER H920_19873 H920_19873 TAB3 TAB3 UBA52 UBA52 IL37 IL37 SKP1 SKP1 Tonsl Tonsl Ikbip Ikbip RBX1 RBX1 ENSFDAP00000023368 ENSFDAP00000023368 PTPN5 PTPN5 H920_07462 H920_07462 PELI2 PELI2 MYD88 MYD88 IL1A IL1A IL1RL1 IL1RL1 SIGIRR SIGIRR MAP2K6 MAP2K6 KHNYN KHNYN TIFA TIFA H920_07431 H920_07431 GSDMD GSDMD IL18R1 IL18R1 LRRC45 LRRC45 USP14 USP14 PTPN21 PTPN21 IL18RAP IL18RAP APP APP Gsap Gsap
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC104864168Cathepsin G; Belongs to the peptidase S1 family. (246 aa)
ENSFDAP00000006648annotation not available (129 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (616 aa)
Usp18Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (60 aa)
ENSFDAP00000000117annotation not available (223 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (619 aa)
Map3k20Mitogen-activated protein kinase kinase kinase MLT. (671 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
BTRCF-box/WD repeat-containing protein 1A. (589 aa)
LRRC34Leucine-rich repeat-containing protein 34. (402 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
IL36RNInterleukin-1. (156 aa)
NLRX1NLR family member X1. (972 aa)
IL13Interleukin 13. (133 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
IL1RNInterleukin-1. (162 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (453 aa)
IL36AInterleukin-1. (152 aa)
TOLLIPToll interacting protein. (270 aa)
Il18Interleukin-18. (293 aa)
S100BProtein S100-B; Belongs to the S-100 family. (92 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
Irak4Interleukin-1 receptor-associated kinase 4. (459 aa)
ENSFDAP00000002920annotation not available (87 aa)
MFSD1Major facilitator superfamily domain-containing protein 1. (465 aa)
LRRC71Leucine-rich repeat-containing protein 71. (462 aa)
IL1RAPInterleukin-1 receptor accessory protein. (562 aa)
LOC104874823Caspase-12; Belongs to the peptidase C14A family. (449 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LRRC74AUncharacterized protein. (476 aa)
NLRC5Protein NLRC5. (1784 aa)
ALPK1Alpha-protein kinase 1. (1003 aa)
IL33Interleukin-33. (263 aa)
NLRP6NLR family pyrin domain containing 6. (808 aa)
IRAK3Interleukin-1 receptor-associated kinase 3. (489 aa)
RELATranscription factor p65. (545 aa)
IL1R2Interleukin-1 receptor type 2. (422 aa)
LRRC74BLeucine rich repeat containing 74B. (378 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (175 aa)
PTPN14Protein tyrosine phosphatase non-receptor type 14. (1067 aa)
PTPN23Tyrosine-protein phosphatase non-receptor type 23. (1517 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1. (112 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (606 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
IL1RL2Interleukin-1 receptor-like 2. (541 aa)
H920_20354S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
IL1R1Interleukin-1 receptor type 1. (583 aa)
NFKBIANF-kappa-B inhibitor alpha. (224 aa)
PELI3Pellino E3 ubiquitin protein ligase family member 3. (445 aa)
NFKB2Nuclear factor kappa B subunit 2. (752 aa)
IL1RAPL1Interleukin-1 receptor accessory protein-like 1. (696 aa)
N4BP1NEDD4-binding protein 1. (825 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (462 aa)
LOC104874822Caspase-1; Belongs to the peptidase C14A family. (434 aa)
STAT3Signal transducer and activator of transcription. (758 aa)
SQSTM1Sequestosome-1. (400 aa)
ENSFDAP00000017776annotation not available (72 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (894 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
Hmgb1High mobility group protein B1. (215 aa)
H920_15675S-phase kinase-associated protein 1; Belongs to the SKP1 family. (135 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
H920_01229Cullin-1; Belongs to the cullin family. (265 aa)
UbcPolyubiquitin-B. (235 aa)
ENSFDAP00000018414annotation not available (666 aa)
IL1F10Interleukin-1. (152 aa)
H920_06373High mobility group-T protein. (197 aa)
IL36GInterleukin 36 gamma. (179 aa)
NFKBIBNF-kappa-B inhibitor beta. (358 aa)
LRRC14Leucine-rich repeat-containing protein 14. (493 aa)
H920_16633High mobility group protein B1. (166 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
PTPN20Protein tyrosine phosphatase non-receptor type 20. (315 aa)
IKBKGNF-kappa-B essential modulator. (417 aa)
AGERAdvanced glycosylation end product-specific receptor. (418 aa)
H920_19873Serum amyloid A-4 protein. (129 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
UBA52KxDL motif containing 1. (232 aa)
IL37Interleukin-1. (183 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (188 aa)
TonslTonsoku-like protein. (64 aa)
IkbipIKBKB interacting protein. (339 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
ENSFDAP00000023368annotation not available (137 aa)
PTPN5Tyrosine-protein phosphatase non-receptor type 5. (541 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
PELI2Protein pellino like protein 2. (351 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
IL1RL1Interleukin-1 receptor-like 1. (555 aa)
SIGIRRSingle Ig and TIR domain containing. (408 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
KHNYNProtein KHNYN. (670 aa)
TIFATRAF-interacting protein with FHA domain-containing protein A. (185 aa)
H920_07431S-phase kinase-associated protein 1; Belongs to the SKP1 family. (136 aa)
GSDMDGasdermin-D. (477 aa)
IL18R1Interleukin 18 receptor 1. (511 aa)
LRRC45Leucine-rich repeat-containing protein 45. (662 aa)
USP14Ubiquitin specific peptidase 14. (440 aa)
PTPN21Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1134 aa)
IL18RAPInterleukin-18 receptor accessory protein. (570 aa)
APPAmyloid beta A4 protein. (766 aa)
GsapGamma-secretase-activating protein. (175 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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