19 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RSPO1	R-spondin-1. (266 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	FZD4	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
	LGR6	Leucine-rich repeat-containing G-protein coupled receptor 6. (774 aa)
	ENSFDAP00000012020	annotation not available (123 aa)
	FZD8	Frizzled class receptor 8. (409 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
	LRTM1	Leucine-rich repeat and transmembrane domain-containing protein 1. (346 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1645 aa)
	ENSFDAP00000002920	annotation not available (87 aa)
	LRP6	Low-density lipoprotein receptor-related protein 6. (1463 aa)
	USP8	Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1080 aa)
	FZD6	Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (596 aa)
	RSPO2	R-spondin-2. (211 aa)
	LGR5	Leucine-rich repeat-containing G-protein coupled receptor 5. (871 aa)
	RSPO3	R-spondin-3. (244 aa)
	Rnf43	RING finger protein 43. (782 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	Ubc	Polyubiquitin-B. (235 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFDAP00000002920	RPS27A	ENSFDAP00000002920	ENSFDAP00000014104	annotation not available	Ubiquitin-40S ribosomal protein S27a.	0.998
ENSFDAP00000002920	Rnf43	ENSFDAP00000002920	ENSFDAP00000022578	annotation not available	RING finger protein 43.	0.756
ENSFDAP00000002920	UBA52	ENSFDAP00000002920	ENSFDAP00000022032	annotation not available	KxDL motif containing 1.	0.826
ENSFDAP00000002920	USP8	ENSFDAP00000002920	ENSFDAP00000007630	annotation not available	Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family.	0.915
ENSFDAP00000002920	Ubc	ENSFDAP00000002920	ENSFDAP00000018389	annotation not available	Polyubiquitin-B.	0.987
ENSFDAP00000012020	LGR5	ENSFDAP00000012020	ENSFDAP00000010126	annotation not available	Leucine-rich repeat-containing G-protein coupled receptor 5.	0.946
ENSFDAP00000012020	LGR6	ENSFDAP00000012020	ENSFDAP00000014005	annotation not available	Leucine-rich repeat-containing G-protein coupled receptor 6.	0.957
ENSFDAP00000012020	LRTM1	ENSFDAP00000012020	ENSFDAP00000011084	annotation not available	Leucine-rich repeat and transmembrane domain-containing protein 1.	0.538
ENSFDAP00000012020	RSPO1	ENSFDAP00000012020	ENSFDAP00000017520	annotation not available	R-spondin-1.	0.901
ENSFDAP00000012020	RSPO3	ENSFDAP00000012020	ENSFDAP00000010904	annotation not available	R-spondin-3.	0.905
ENSFDAP00000012020	Rnf43	ENSFDAP00000012020	ENSFDAP00000022578	annotation not available	RING finger protein 43.	0.958
FZD4	FZD6	ENSFDAP00000014026	ENSFDAP00000008915	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.673
FZD4	FZD8	ENSFDAP00000014026	ENSFDAP00000012005	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 8.	0.556
FZD4	LGR5	ENSFDAP00000014026	ENSFDAP00000010126	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Leucine-rich repeat-containing G-protein coupled receptor 5.	0.414
FZD4	LRP5	ENSFDAP00000014026	ENSFDAP00000001017	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.970
FZD4	LRP6	ENSFDAP00000014026	ENSFDAP00000003197	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein 6.	0.970
FZD4	RPS27A	ENSFDAP00000014026	ENSFDAP00000014104	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Ubiquitin-40S ribosomal protein S27a.	0.721
FZD4	Rnf43	ENSFDAP00000014026	ENSFDAP00000022578	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	RING finger protein 43.	0.923
FZD4	USP8	ENSFDAP00000014026	ENSFDAP00000007630	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family.	0.627
FZD4	Ubc	ENSFDAP00000014026	ENSFDAP00000018389	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Polyubiquitin-B.	0.753