42 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JAK2	Tyrosine-protein kinase. (1132 aa)
	CRKL	Crk-like protein. (303 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
	Il2rg	Cytokine receptor common subunit gamma. (386 aa)
	Stat5b	Signal transducer and activator of transcription 5B. (736 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
	SYK	Tyrosine-protein kinase. (629 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
	H920_15994	Tyrosine-protein kinase. (1024 aa)
	ENSFDAP00000002920	annotation not available (87 aa)
	IL5RA	Interleukin-5 receptor subunit alpha. (351 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (851 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha. (343 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	GAB2	GRB2-associated-binding protein 2. (636 aa)
	LOC104855306	Cytokine receptor common subunit beta. (652 aa)
	SOS1	Son of sevenless like protein 1. (1289 aa)
	VAV1	Proto-oncogene vav. (714 aa)
	INPPL1	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2. (1225 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	H920_14855	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (262 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	INPP5D	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1. (1140 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	IL2RB	Interleukin-2 receptor subunit beta. (528 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type 11. (600 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	Il5	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
	SHC1	SHC-transforming protein 1. (583 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	Pik3r2	Phosphoinositide-3-kinase regulatory subunit 2. (71 aa)
	Ywhaz	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
	CRK	CRK proto-oncogene, adaptor protein. (247 aa)
	TEC	Tyrosine-protein kinase. (632 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	JAK1	Tyrosine-protein kinase. (1153 aa)
	CSF2	Uncharacterized protein. (144 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1. (1211 aa)
	Pik3r3	Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
	H920_06884	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	CRK	ENSFDAP00000003307	ENSFDAP00000019051	E3 ubiquitin-protein ligase CBL.	CRK proto-oncogene, adaptor protein.	0.995
CBL	CRKL	ENSFDAP00000003307	ENSFDAP00000014876	E3 ubiquitin-protein ligase CBL.	Crk-like protein.	0.996
CBL	ENSFDAP00000002920	ENSFDAP00000003307	ENSFDAP00000002920	E3 ubiquitin-protein ligase CBL.	annotation not available	0.900
CBL	FYN	ENSFDAP00000003307	ENSFDAP00000011404	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.985
CBL	GRB2	ENSFDAP00000003307	ENSFDAP00000004772	E3 ubiquitin-protein ligase CBL.	Growth factor receptor-bound protein 2.	0.995
CBL	H920_06884	ENSFDAP00000003307	ENSFDAP00000015177	E3 ubiquitin-protein ligase CBL.	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family.	0.481
CBL	H920_14855	ENSFDAP00000003307	ENSFDAP00000012374	E3 ubiquitin-protein ligase CBL.	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family.	0.481
CBL	H920_15994	ENSFDAP00000003307	ENSFDAP00000001901	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.669
CBL	INPP5D	ENSFDAP00000003307	ENSFDAP00000011839	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1.	0.621
CBL	INPPL1	ENSFDAP00000003307	ENSFDAP00000007310	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2.	0.842
CBL	JAK1	ENSFDAP00000003307	ENSFDAP00000018314	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.710
CBL	JAK2	ENSFDAP00000003307	ENSFDAP00000018107	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.719
CBL	LYN	ENSFDAP00000003307	ENSFDAP00000021246	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.974
CBL	PIK3CA	ENSFDAP00000003307	ENSFDAP00000020092	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.889
CBL	PIK3CB	ENSFDAP00000003307	ENSFDAP00000001430	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family.	0.938
CBL	PIK3CD	ENSFDAP00000003307	ENSFDAP00000012960	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.876
CBL	PIK3R1	ENSFDAP00000003307	ENSFDAP00000020905	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit alpha.	0.994
CBL	PTPN11	ENSFDAP00000003307	ENSFDAP00000000436	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type 11.	0.857
CBL	PTPN6	ENSFDAP00000003307	ENSFDAP00000012210	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.717
CBL	Pik3r2	ENSFDAP00000003307	ENSFDAP00000019939	E3 ubiquitin-protein ligase CBL.	Phosphoinositide-3-kinase regulatory subunit 2.	0.959