STRINGSTRING
TTC6 TTC6 BIRC3 BIRC3 Fas Fas TRADD TRADD FADD FADD Tnfrsf10b Tnfrsf10b TRAF2 TRAF2 PELI1 PELI1 FLOT2 FLOT2 ENSFDAP00000002789 ENSFDAP00000002789 ENSFDAP00000002920 ENSFDAP00000002920 FLOT1 FLOT1 UBA52 UBA52 BIRC2 BIRC2 STUB1 STUB1 OGT OGT TNFSF10 TNFSF10 CFLAR CFLAR PDCD6IP PDCD6IP RIPK1 RIPK1 SDCBP SDCBP Faslg Faslg RPS27A RPS27A CASP8 CASP8 LOC104849456 LOC104849456 XIAP XIAP Ubc Ubc CDC37 CDC37
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTC6Tetratricopeptide repeat domain 6. (538 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (644 aa)
FasTumor necrosis factor receptor superfamily member 6. (290 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (310 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
Tnfrsf10bTumor necrosis factor receptor superfamily member 10B. (417 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (412 aa)
ENSFDAP00000002789annotation not available (79 aa)
ENSFDAP00000002920annotation not available (87 aa)
FLOT1Flotillin 1. (380 aa)
UBA52KxDL motif containing 1. (232 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (618 aa)
STUB1STIP1 homology and U box-containing protein 1. (250 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1046 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (289 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (435 aa)
PDCD6IPProgrammed cell death 6-interacting protein. (797 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (660 aa)
SDCBPSyntenin-1. (241 aa)
FaslgTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (69 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (462 aa)
LOC104849456E3 ubiquitin-protein ligase parkin. (243 aa)
XIAPBaculoviral IAP repeat-containing protein 4. (497 aa)
UbcPolyubiquitin-B. (235 aa)
CDC37Cell division cycle 37. (377 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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