STRINGSTRING
CHMP2A CHMP2A Tnfrsf10b Tnfrsf10b ENSFDAP00000000117 ENSFDAP00000000117 FADD FADD ENSFDAP00000002920 ENSFDAP00000002920 ENSFDAP00000002828 ENSFDAP00000002828 ENSFDAP00000002789 ENSFDAP00000002789 FLOT2 FLOT2 Il18 Il18 ENSFDAP00000002251 ENSFDAP00000002251 PELI1 PELI1 BAX BAX TRAF2 TRAF2 CHMP4B CHMP4B BAK1 BAK1 H920_06373 H920_06373 GSDMA GSDMA UBA52 UBA52 MDP1 MDP1 TNFSF10 TNFSF10 OGT OGT STUB1 STUB1 TRADD TRADD Fas Fas LOC104874823 LOC104874823 LOC104864185 LOC104864185 BIRC3 BIRC3 IRF2 IRF2 TTC6 TTC6 CFLAR CFLAR IL1A IL1A H920_16633 H920_16633 H920_05903 H920_05903 FLOT1 FLOT1 LOC104863283 LOC104863283 BIRC2 BIRC2 CDC37 CDC37 Ubc Ubc Il1b Il1b LOC104864184 LOC104864184 Gsdme Gsdme XIAP XIAP Hmgb1 Hmgb1 LOC104849456 LOC104849456 CHMP7 CHMP7 LOC104874822 LOC104874822 CASP8 CASP8 NPVF NPVF LOC104864167 LOC104864167 IRF1 IRF1 GZMH GZMH LOC104864952 LOC104864952 CHMP6 CHMP6 RPS27A RPS27A ENSFDAP00000013841 ENSFDAP00000013841 CHMP4C CHMP4C GSDMD GSDMD Faslg Faslg SDCBP SDCBP LOC104861153 LOC104861153 CHMP2B CHMP2B RIPK1 RIPK1 Casp3 Casp3 PDCD6IP PDCD6IP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHMP2ACharged multivesicular body protein 2a. (222 aa)
Tnfrsf10bTumor necrosis factor receptor superfamily member 10B. (417 aa)
ENSFDAP00000000117annotation not available (223 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ENSFDAP00000002920annotation not available (87 aa)
ENSFDAP00000002828annotation not available (86 aa)
ENSFDAP00000002789annotation not available (79 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (412 aa)
Il18Interleukin-18. (293 aa)
ENSFDAP00000002251annotation not available (88 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
BAXApoptosis regulator BAX. (180 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
CHMP4BCharged multivesicular body protein 4b. (224 aa)
BAK1Bcl-2 like proteinous antagonist/killer. (212 aa)
H920_06373High mobility group-T protein. (197 aa)
GSDMAGasdermin-A. (434 aa)
UBA52KxDL motif containing 1. (232 aa)
MDP1Magnesium-dependent phosphatase 1. (161 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (289 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1046 aa)
STUB1STIP1 homology and U box-containing protein 1. (250 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (310 aa)
FasTumor necrosis factor receptor superfamily member 6. (290 aa)
LOC104874823Caspase-12; Belongs to the peptidase C14A family. (449 aa)
LOC104864185Granzyme-like protein 1; Belongs to the peptidase S1 family. (254 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (644 aa)
IRF2Interferon regulatory factor. (349 aa)
TTC6Tetratricopeptide repeat domain 6. (538 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (435 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
H920_16633High mobility group protein B1. (166 aa)
H920_05903Charged multivesicular body protein 3. (197 aa)
FLOT1Flotillin 1. (380 aa)
LOC104863283Charged multivesicular body protein 3. (221 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (618 aa)
CDC37Cell division cycle 37. (377 aa)
UbcPolyubiquitin-B. (235 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
LOC104864184Granzyme B(G,H); Belongs to the peptidase S1 family. (235 aa)
GsdmeNon-syndromic hearing impairment protein 5. (123 aa)
XIAPBaculoviral IAP repeat-containing protein 4. (497 aa)
Hmgb1High mobility group protein B1. (215 aa)
LOC104849456E3 ubiquitin-protein ligase parkin. (243 aa)
CHMP7Charged multivesicular body protein 7. (448 aa)
LOC104874822Caspase-1; Belongs to the peptidase C14A family. (434 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (462 aa)
NPVFNeuropeptide VF precursor. (173 aa)
LOC104864167Granzyme B; Belongs to the peptidase S1 family. (247 aa)
IRF1Interferon regulatory factor. (326 aa)
GZMHGranzyme H; Belongs to the peptidase S1 family. (245 aa)
LOC104864952Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CHMP6Charged multivesicular body protein 6. (192 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
ENSFDAP00000013841annotation not available (257 aa)
CHMP4CCharged multivesicular body protein 4c. (229 aa)
GSDMDGasdermin-D. (477 aa)
FaslgTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (69 aa)
SDCBPSyntenin-1. (241 aa)
LOC104861153Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
CHMP2BCharged multivesicular body protein 2b. (213 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (660 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
PDCD6IPProgrammed cell death 6-interacting protein. (797 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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