STRINGSTRING
CHMP7 CHMP7 FADD FADD ENSFDAP00000000117 ENSFDAP00000000117 Tnfrsf10b Tnfrsf10b CHMP4B CHMP4B IGDCC4 IGDCC4 TRAF2 TRAF2 BAX BAX H920_06972 H920_06972 OMA1 OMA1 DSG1 DSG1 TMEM198 TMEM198 PKP1 PKP1 PPP3CC PPP3CC HMGB2 HMGB2 PELI1 PELI1 PLEC PLEC ACIN1 ACIN1 APIP APIP YWHAG YWHAG ENSFDAP00000002251 ENSFDAP00000002251 Il18 Il18 YWHAB YWHAB FLOT2 FLOT2 ENSFDAP00000002673 ENSFDAP00000002673 APC APC ENSFDAP00000002789 ENSFDAP00000002789 ENSFDAP00000002828 ENSFDAP00000002828 ROCK1 ROCK1 ENSFDAP00000002920 ENSFDAP00000002920 CASP7 CASP7 APC2 APC2 CHMP2A CHMP2A TTC6 TTC6 IRF2 IRF2 BIRC3 BIRC3 LOC104864185 LOC104864185 LOC104874823 LOC104874823 MAPK8 MAPK8 BMX BMX LMNA LMNA Fas Fas TRADD TRADD STUB1 STUB1 KPNA1 KPNA1 SPTAN1 SPTAN1 BAD BAD OGT OGT BMF BMF Septin4 Septin4 Septin5 Septin5 DBNL DBNL Hp1bp3 Hp1bp3 H920_09786 H920_09786 TNFSF10 TNFSF10 PRKCD PRKCD CASP6 CASP6 TJP1 TJP1 SCIN SCIN MAPT MAPT DAPK1 DAPK1 AVEN AVEN IL1A IL1A CFLAR CFLAR SH3GLB1 SH3GLB1 BOK BOK Tjp2 Tjp2 LMNTD1 LMNTD1 PDCD6IP PDCD6IP Casp3 Casp3 GSN GSN DFFB DFFB NMT1 NMT1 ENSFDAP00000010119 ENSFDAP00000010119 RIPK1 RIPK1 Fnta Fnta CAPG CAPG LOC104859199 LOC104859199 LMNB1 LMNB1 YWHAE YWHAE Stk24 Stk24 CHMP2B CHMP2B GAS2 GAS2 H1-6 H1-6 APAF1 APAF1 LOC104861153 LOC104861153 SDCBP SDCBP CLSPN CLSPN DAPK2 DAPK2 LOC104871855 LOC104871855 SFN SFN H920_14855 H920_14855 KPNB1 KPNB1 BCL2L2 BCL2L2 Faslg Faslg DNM1L DNM1L GSDMD GSDMD H920_09656 H920_09656 OPA1 OPA1 CHMP4C CHMP4C ENSFDAP00000013841 ENSFDAP00000013841 ENSFDAP00000014004 ENSFDAP00000014004 CASP9 CASP9 RPS27A RPS27A CHMP6 CHMP6 LOC104864952 LOC104864952 LOC104855197 LOC104855197 GZMH GZMH YWHAH YWHAH H920_06884 H920_06884 DCC DCC ENSFDAP00000015575 ENSFDAP00000015575 Bid Bid IRF1 IRF1 LOC104864167 LOC104864167 CDH1 CDH1 NPVF NPVF ENSFDAP00000016651 ENSFDAP00000016651 CASP8 CASP8 LOC104874822 LOC104874822 BCAP29 BCAP29 BCL2L1 BCL2L1 Hmgb3 Hmgb3 APPL1 APPL1 LOC104849456 LOC104849456 LOC104876601 LOC104876601 Hmgb1 Hmgb1 PTK2 PTK2 XIAP XIAP Gsdme Gsdme LOC104864184 LOC104864184 PPP3R1 PPP3R1 Il1b Il1b Ubc Ubc Dynll1 Dynll1 LMNB2 LMNB2 MAP2 MAP2 CDC37 CDC37 BAK1 BAK1 DSG3 DSG3 BCL2L11 BCL2L11 Ctnnb1 Ctnnb1 H920_06373 H920_06373 VIM VIM GSDMA GSDMA Ywhaz Ywhaz MAPK3 MAPK3 OCLN OCLN IGDCC3 IGDCC3 H920_16633 H920_16633 H920_05903 H920_05903 LMNTD2 LMNTD2 MAPK1 MAPK1 STK26 STK26 PRKCQ PRKCQ FLOT1 FLOT1 ADD1 ADD1 Diablo Diablo UNC5B UNC5B LOC104863283 LOC104863283 DSP DSP SH3GLB2 SH3GLB2 LOC104851822 LOC104851822 UBA52 UBA52 TJP3 TJP3 SEPTIN4 SEPTIN4 DYNLL2 DYNLL2 BIRC2 BIRC2 APPL2 APPL2 BCAP31 BCAP31 MDP1 MDP1 YWHAQ YWHAQ STK25 STK25
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHMP7Charged multivesicular body protein 7. (448 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ENSFDAP00000000117annotation not available (223 aa)
Tnfrsf10bTumor necrosis factor receptor superfamily member 10B. (417 aa)
CHMP4BCharged multivesicular body protein 4b. (224 aa)
IGDCC4Immunoglobulin superfamily DCC subclass member 4-like. (819 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
BAXApoptosis regulator BAX. (180 aa)
H920_06972DNAation factor subunit alpha. (181 aa)
OMA1OMA1 zinc metallopeptidase. (529 aa)
DSG1Desmoglein-1-alpha; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1154 aa)
TMEM198Transmembrane protein 198. (360 aa)
PKP1Plakophilin-1. (658 aa)
PPP3CCSerine/threonine-protein phosphatase. (493 aa)
HMGB2High mobility group box 2. (160 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
PLECPlectin. (4691 aa)
ACIN1Apoptotic chromatin condensation inducer in the nucleus. (1339 aa)
APIPPutative methylthioribulose-1-phosphate dehydratase. (242 aa)
YWHAG14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
ENSFDAP00000002251annotation not available (88 aa)
Il18Interleukin-18. (293 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (412 aa)
ENSFDAP00000002673annotation not available (318 aa)
APCAdenomatous polyposis coli protein. (2857 aa)
ENSFDAP00000002789annotation not available (79 aa)
ENSFDAP00000002828annotation not available (86 aa)
ROCK1Rho-associated protein kinase 1; Belongs to the peptidase C19 family. (1368 aa)
ENSFDAP00000002920annotation not available (87 aa)
CASP7Caspase-7; Belongs to the peptidase C14A family. (314 aa)
APC2Adenomatous polyposis coli protein 2. (1982 aa)
CHMP2ACharged multivesicular body protein 2a. (222 aa)
TTC6Tetratricopeptide repeat domain 6. (538 aa)
IRF2Interferon regulatory factor. (349 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (644 aa)
LOC104864185Granzyme-like protein 1; Belongs to the peptidase S1 family. (254 aa)
LOC104874823Caspase-12; Belongs to the peptidase C14A family. (449 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
BMXTyrosine-protein kinase. (655 aa)
LMNAPrelamin-A/C; Belongs to the intermediate filament family. (453 aa)
FasTumor necrosis factor receptor superfamily member 6. (290 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (310 aa)
STUB1STIP1 homology and U box-containing protein 1. (250 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
SPTAN1Spectrin alpha chain, brain. (2498 aa)
BADBcl2 antagonist of cell death. (162 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1046 aa)
BMFBcl-2-modifying factor. (184 aa)
Septin4Septin 4. (471 aa)
Septin5Septin-5. (369 aa)
DBNLDrebrin-like protein. (414 aa)
Hp1bp3Heterochromatin protein 1-binding protein 3. (579 aa)
H920_09786Death-associated protein kinase 3; Belongs to the protein kinase superfamily. (376 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (289 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
CASP6Caspase-6; Belongs to the peptidase C14A family. (272 aa)
TJP1Tight junction protein ZO-1; Belongs to the MAGUK family. (1774 aa)
SCINAdseverin. (648 aa)
MAPTMicrotubule-associated protein. (432 aa)
DAPK1Death-associated protein kinase 1. (1430 aa)
AVENDUF2012 domain-containing protein. (265 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (435 aa)
SH3GLB1Endophilin-B1. (370 aa)
BOKBcl-2-related ovarian killer protein. (146 aa)
Tjp2Tight junction protein ZO-2; Belongs to the MAGUK family. (1143 aa)
LMNTD1Intermediate filament tail domain-containing protein 1. (397 aa)
PDCD6IPProgrammed cell death 6-interacting protein. (797 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
GSNGelsolin. (776 aa)
DFFBDNAation factor subunit beta. (310 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
ENSFDAP00000010119annotation not available (355 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (660 aa)
FntaProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha. (348 aa)
CAPGMacrophage-capping protein. (349 aa)
LOC104859199Desmoglein-2. (504 aa)
LMNB1Lamin-B1; Belongs to the intermediate filament family. (516 aa)
YWHAE14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
Stk24Serine/threonine-protein kinase 24. (433 aa)
CHMP2BCharged multivesicular body protein 2b. (213 aa)
GAS2Growth arrest-specific protein 2. (314 aa)
H1-6Histone H1t. (216 aa)
APAF1Apoptotic protease-activating factor 1. (1249 aa)
LOC104861153Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
SDCBPSyntenin-1. (241 aa)
CLSPNClaspin. (1338 aa)
DAPK2Death-associated protein kinase 3. (370 aa)
LOC104871855Histone H1oo. (338 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
H920_1485514-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (262 aa)
KPNB1Importin subunit beta-1. (848 aa)
BCL2L2Polyadenylate-binding protein 2. (193 aa)
FaslgTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (69 aa)
DNM1LDynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (736 aa)
GSDMDGasdermin-D. (477 aa)
H920_09656Catenin beta-1. (83 aa)
OPA1Dynamin-like 120 kDa protein, mitochondrial; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (956 aa)
CHMP4CCharged multivesicular body protein 4c. (229 aa)
ENSFDAP00000013841annotation not available (257 aa)
ENSFDAP00000014004annotation not available (328 aa)
CASP9Caspase-9; Belongs to the peptidase C14A family. (406 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
CHMP6Charged multivesicular body protein 6. (192 aa)
LOC104864952Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC10485519714-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
GZMHGranzyme H; Belongs to the peptidase S1 family. (245 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (217 aa)
H920_0688414-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
DCCNetrin receptor DCC. (1073 aa)
ENSFDAP00000015575annotation not available (193 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (187 aa)
IRF1Interferon regulatory factor. (326 aa)
LOC104864167Granzyme B; Belongs to the peptidase S1 family. (247 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (895 aa)
NPVFNeuropeptide VF precursor. (173 aa)
ENSFDAP00000016651annotation not available (428 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (462 aa)
LOC104874822Caspase-1; Belongs to the peptidase C14A family. (434 aa)
BCAP29B cell receptor associated protein 29. (241 aa)
BCL2L1Bcl-2-like protein 1. (233 aa)
Hmgb3High mobility group protein B3. (198 aa)
APPL1DCC-interacting protein 13-alpha. (690 aa)
LOC104849456E3 ubiquitin-protein ligase parkin. (243 aa)
LOC104876601Transmembrane protein 198-B. (350 aa)
Hmgb1High mobility group protein B1. (215 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1083 aa)
XIAPBaculoviral IAP repeat-containing protein 4. (497 aa)
GsdmeNon-syndromic hearing impairment protein 5. (123 aa)
LOC104864184Granzyme B(G,H); Belongs to the peptidase S1 family. (235 aa)
PPP3R1Calcineurin subunit B type 1. (164 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
UbcPolyubiquitin-B. (235 aa)
Dynll1Dynein light chain. (89 aa)
LMNB2Lamin B2. (451 aa)
MAP2Microtubule-associated protein. (1815 aa)
CDC37Cell division cycle 37. (377 aa)
BAK1Bcl-2 like proteinous antagonist/killer. (212 aa)
DSG3Desmoglein 3. (986 aa)
BCL2L11BCL2 like 11. (195 aa)
Ctnnb1Catenin beta-1. (781 aa)
H920_06373High mobility group-T protein. (197 aa)
VIMVimentin; Belongs to the intermediate filament family. (411 aa)
GSDMAGasdermin-A. (434 aa)
Ywhaz14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
OCLNOccludin. (523 aa)
IGDCC3Immunoglobulin superfamily DCC subclass member 3. (712 aa)
H920_16633High mobility group protein B1. (166 aa)
H920_05903Charged multivesicular body protein 3. (197 aa)
LMNTD2LTD domain-containing protein. (642 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
STK26Serine/threonine-protein kinase MST4. (416 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
FLOT1Flotillin 1. (380 aa)
ADD1Alpha-adducin. (730 aa)
DiabloDiablo like protein, mitochondrial. (233 aa)
UNC5BNetrin receptor UNC5B. (945 aa)
LOC104863283Charged multivesicular body protein 3. (221 aa)
DSPDesmoplakin. (2844 aa)
SH3GLB2Endophilin-B2. (383 aa)
LOC104851822Dynein light chain. (89 aa)
UBA52KxDL motif containing 1. (232 aa)
TJP3Tight junction protein 3. (809 aa)
SEPTIN4Uncharacterized protein. (500 aa)
DYNLL2Dynein light chain. (89 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (618 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (644 aa)
BCAP31B-cell receptor-associated protein 31. (247 aa)
MDP1Magnesium-dependent phosphatase 1. (161 aa)
YWHAQ14-3-3 protein theta; Belongs to the 14-3-3 family. (304 aa)
STK25Serine/threonine-protein kinase 25. (417 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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