STRINGSTRING
RACK1 RACK1 SHARPIN SHARPIN CYLD CYLD IKBKG IKBKG UBE2D2 UBE2D2 UBA52 UBA52 BIRC2 BIRC2 BIRC3 BIRC3 TRAF1 TRAF1 ENSFDAP00000003729 ENSFDAP00000003729 OTULINL OTULINL ENSFDAP00000002920 ENSFDAP00000002920 OPTN OPTN IKBKB IKBKB MAPKAPK2 MAPKAPK2 TMEM198 TMEM198 OTUD7B OTUD7B Ikbke Ikbke H920_15109 H920_15109 TRAF2 TRAF2 FADD FADD UBE2D1 UBE2D1 USP2 USP2 CLIP4 CLIP4 TNF TNF SPATA2 SPATA2 TAX1BP1 TAX1BP1 TRADD TRADD STUB1 STUB1 ENSFDAP00000005475 ENSFDAP00000005475 MADD MADD CLIP3 CLIP3 ENSFDAP00000007247 ENSFDAP00000007247 OTULIN OTULIN CFLAR CFLAR LOC104856727 LOC104856727 NFATC4 NFATC4 WDR31 WDR31 ENSFDAP00000010206 ENSFDAP00000010206 RIPK1 RIPK1 RBCK1 RBCK1 Rnf31 Rnf31 RPS27A RPS27A SPPL2B SPPL2B SPPL2C SPPL2C ULK2 ULK2 SPPL2A SPPL2A Chuk Chuk CASP8 CASP8 LOC104876601 LOC104876601 TBK1 TBK1 XIAP XIAP Ubc Ubc ENSFDAP00000018414 ENSFDAP00000018414 USP4 USP4 USP21 USP21 TNFAIP3 TNFAIP3 ULK1 ULK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RACK1Guanine nucleotide-binding protein subunit beta-2-like 1. (317 aa)
SHARPINSharpin. (414 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (951 aa)
IKBKGNF-kappa-B essential modulator. (417 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D4; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
UBA52KxDL motif containing 1. (232 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (618 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (644 aa)
TRAF1TNF receptor-associated factor. (415 aa)
ENSFDAP00000003729annotation not available (135 aa)
OTULINLProtein FAM105A. (284 aa)
ENSFDAP00000002920annotation not available (87 aa)
OPTNOptineurin. (599 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (399 aa)
TMEM198Transmembrane protein 198. (360 aa)
OTUD7BOTU domain-containing protein 7B. (843 aa)
IkbkeInhibitor of nuclear factor kappa-B kinase subunit epsilon. (130 aa)
H920_15109CAP-Gly domain-containing linker protein 1. (365 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (612 aa)
CLIP4CAP-Gly domain containing linker protein family member 4. (702 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
SPATA2Spermatogenesis-associated protein 2. (514 aa)
TAX1BP1Tax1-binding protein 1 like protein. (839 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (310 aa)
STUB1STIP1 homology and U box-containing protein 1. (250 aa)
ENSFDAP00000005475annotation not available (139 aa)
MADDMAP kinase activating death domain. (1595 aa)
CLIP3CAP-Gly domain-containing linker protein 3. (547 aa)
ENSFDAP00000007247annotation not available (119 aa)
OTULINProtein FAM105B. (301 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (435 aa)
LOC104856727Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
NFATC4Nuclear factor of activated T-cells, cytoplasmic 4. (868 aa)
WDR31WD repeat-containing protein 31. (366 aa)
ENSFDAP00000010206annotation not available (133 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (660 aa)
RBCK1RanBP-type and C3HC4-type zinc finger-containing protein 1. (510 aa)
Rnf31RING finger protein 31. (1069 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
SPPL2BSignal peptide peptidase-like 2B. (583 aa)
SPPL2CSignal peptide peptidase-like 2C. (552 aa)
ULK2Serine/threonine-protein kinase ULK2. (1057 aa)
SPPL2ASignal peptide peptidase like 2A. (499 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (462 aa)
LOC104876601Transmembrane protein 198-B. (350 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
XIAPBaculoviral IAP repeat-containing protein 4. (497 aa)
UbcPolyubiquitin-B. (235 aa)
ENSFDAP00000018414annotation not available (666 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (964 aa)
USP21Ubiquitin carboxyl-terminal hydrolase 21; Belongs to the peptidase C19 family. (565 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (755 aa)
ULK1Serine/threonine-protein kinase ULK1. (1043 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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