STRINGSTRING
OPTN OPTN UBA52 UBA52 ENSFDAP00000002920 ENSFDAP00000002920 BIRC3 BIRC3 BIRC2 BIRC2 TRAF1 TRAF1 USP2 USP2 TNF TNF SPATA2 SPATA2 TRADD TRADD RIPK1 RIPK1 RBCK1 RBCK1 Rnf31 Rnf31 RPS27A RPS27A MAP3K7 MAP3K7 Chuk Chuk XIAP XIAP Ubc Ubc ENSFDAP00000018414 ENSFDAP00000018414 USP4 USP4 USP21 USP21 TNFAIP3 TNFAIP3 RACK1 RACK1 SHARPIN SHARPIN CYLD CYLD IKBKG IKBKG TAB3 TAB3 TAB1 TAB1 TRAF2 TRAF2 TAB2 TAB2 OTUD7B OTUD7B IKBKB IKBKB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OPTNOptineurin. (599 aa)
UBA52KxDL motif containing 1. (232 aa)
ENSFDAP00000002920annotation not available (87 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (644 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (618 aa)
TRAF1TNF receptor-associated factor. (415 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (612 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
SPATA2Spermatogenesis-associated protein 2. (514 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (310 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (660 aa)
RBCK1RanBP-type and C3HC4-type zinc finger-containing protein 1. (510 aa)
Rnf31RING finger protein 31. (1069 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (606 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
XIAPBaculoviral IAP repeat-containing protein 4. (497 aa)
UbcPolyubiquitin-B. (235 aa)
ENSFDAP00000018414annotation not available (666 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (964 aa)
USP21Ubiquitin carboxyl-terminal hydrolase 21; Belongs to the peptidase C19 family. (565 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (755 aa)
RACK1Guanine nucleotide-binding protein subunit beta-2-like 1. (317 aa)
SHARPINSharpin. (414 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (951 aa)
IKBKGNF-kappa-B essential modulator. (417 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
OTUD7BOTU domain-containing protein 7B. (843 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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