STRINGSTRING
COPS3 COPS3 PIAS1 PIAS1 INO80E INO80E VWA5A VWA5A ENSFDAP00000017776 ENSFDAP00000017776 VWA5B2 VWA5B2 DDB2 DDB2 ENSFDAP00000017753 ENSFDAP00000017753 VTCN1 VTCN1 INO80 INO80 Sumo3 Sumo3 DDB1 DDB1 RFC4 RFC4 H920_07824 H920_07824 COPS2 COPS2 ENSFDAP00000015308 ENSFDAP00000015308 ACTR5 ACTR5 CDK7 CDK7 SUMO4 SUMO4 ACTR8 ACTR8 GTF2H1 GTF2H1 RPS27A RPS27A Ino80b Ino80b ACTL6A ACTL6A ERCC1 ERCC1 Pold4 Pold4 H920_08542 H920_08542 RAD23B RAD23B GTF2H4 GTF2H4 RFC3 RFC3 RPA3 RPA3 RFC2 RFC2 CUL4B CUL4B INO80C INO80C PARP2 PARP2 H920_07462 H920_07462 PARP1 PARP1 ERCC2 ERCC2 PARP3 PARP3 POLE POLE ENSFDAP00000009158 ENSFDAP00000009158 ENSFDAP00000008979 ENSFDAP00000008979 RCBTB1 RCBTB1 WBP1 WBP1 Cetn2 Cetn2 ZFP42 ZFP42 RPAP3 RPAP3 RFC1 RFC1 UBE2I UBE2I COPS6 COPS6 ENSFDAP00000007168 ENSFDAP00000007168 COPS7B COPS7B CUL4A CUL4A COPS7A COPS7A Sumo2 Sumo2 ENSFDAP00000006648 ENSFDAP00000006648 ATAD5 ATAD5 ENSFDAP00000006063 ENSFDAP00000006063 COPS5 COPS5 ENSFDAP00000004931 ENSFDAP00000004931 VWA5B1 VWA5B1 PIAS3 PIAS3 ERCC4 ERCC4 GTF2H5 GTF2H5 TFPT TFPT INO80D INO80D Yy1 Yy1 KCTD2 KCTD2 ENSFDAP00000002920 ENSFDAP00000002920 CHD1L CHD1L USP45 USP45 ERCC3 ERCC3 RFC5 RFC5 RUVBL1 RUVBL1 LOC104871412 LOC104871412 PCNA PCNA XPA XPA COPS8 COPS8 GTF2H3 GTF2H3 POLK POLK H920_05086 H920_05086 MNAT1 MNAT1 RPA2 RPA2 RBX1 RBX1 CETN3 CETN3 XPC XPC SUMO1 SUMO1 POLD2 POLD2 UBA52 UBA52 UBE2V2 UBE2V2 COPS4 COPS4 MEIOB MEIOB CCNH CCNH NFRKB NFRKB RPA1 RPA1 POLE2 POLE2 WDR76 WDR76 GPS1 GPS1 RAD23A RAD23A RNF111 RNF111 Mcrs1 Mcrs1 RCBTB2 RCBTB2 Pold3 Pold3 POLD1 POLD1 ENSFDAP00000019135 ENSFDAP00000019135 Ubc Ubc POLE3 POLE3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COPS3COP9 signalosome complex subunit 3. (423 aa)
PIAS1E3 SUMO-protein ligase PIAS1. (647 aa)
INO80EINO80 complex subunit E. (243 aa)
VWA5AVon Willebrand factor A domain-containing protein 5A. (805 aa)
ENSFDAP00000017776annotation not available (72 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1019 aa)
DDB2DNA damage-binding protein 2. (296 aa)
ENSFDAP00000017753annotation not available (63 aa)
VTCN1V-set domain-containing T-cell activation inhibitor 1. (282 aa)
INO80DNA helicase INO80. (1559 aa)
Sumo3Small ubiquitin like modifier 3. (115 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
RFC4Replication factor C subunit 4. (333 aa)
H920_07824V-set domain-containing T-cell activation inhibitor 1. (269 aa)
COPS2COP9 signalosome complex subunit 2. (443 aa)
ENSFDAP00000015308annotation not available (503 aa)
ACTR5Actin related protein 5. (602 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
SUMO4Small ubiquitin-related modifier. (95 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
Ino80bINO80 complex subunit B. (349 aa)
ACTL6AActin-like protein 6A; Belongs to the actin family. (429 aa)
ERCC1DNA excision repair protein ERCC-1. (298 aa)
Pold4DNA polymerase delta subunit 4. (107 aa)
H920_08542Centrin-2. (157 aa)
RAD23BUV excision repair protein RAD23 like protein B. (396 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (406 aa)
RFC3Replication factor C subunit 3. (356 aa)
RPA3Replication protein A 14 kDa subunit. (122 aa)
RFC2Replication factor C subunit 2. (316 aa)
CUL4BCullin-4B; Belongs to the cullin family. (888 aa)
INO80CINO80 complex subunit C. (192 aa)
PARP2Poly [ADP-ribose] polymerase. (558 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (973 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit. (760 aa)
PARP3Poly [ADP-ribose] polymerase. (531 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
ENSFDAP00000009158annotation not available (49 aa)
ENSFDAP00000008979annotation not available (180 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (531 aa)
WBP1WW domain-binding protein 1. (304 aa)
Cetn2Centrin-2. (166 aa)
ZFP42Zinc finger protein 42 like protein. (272 aa)
RPAP3RNA polymerase II-associated protein 3. (670 aa)
RFC1Replication factor C subunit 1. (1141 aa)
UBE2ISUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
COPS6COP9 signalosome complex subunit 6. (347 aa)
ENSFDAP00000007168annotation not available (110 aa)
COPS7BCOP9 signalosome complex subunit 7b. (264 aa)
CUL4ACullin 4A. (594 aa)
COPS7ACOP9 signalosome complex subunit 7a. (277 aa)
Sumo2Small ubiquitin-related modifier 3. (88 aa)
ENSFDAP00000006648annotation not available (129 aa)
ATAD5ATPase family AAA domain-containing protein 5. (1822 aa)
ENSFDAP00000006063annotation not available (179 aa)
COPS5COP9 signalosome complex subunit 5. (334 aa)
ENSFDAP00000004931annotation not available (394 aa)
VWA5B1Von Willebrand factor A domain-containing protein 5B1. (1274 aa)
PIAS3E3 SUMO-protein ligase PIAS3. (637 aa)
ERCC4DNA repair endonuclease XPF. (917 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
TFPTTCF3 fusion partner like protein. (252 aa)
INO80DINO80 complex subunit D. (1026 aa)
Yy1YY1 transcription factor. (189 aa)
KCTD2BTB/POZ domain-containing protein KCTD2. (222 aa)
ENSFDAP00000002920annotation not available (87 aa)
CHD1LChromodomain-helicase-DNA-binding protein 1-like. (856 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (811 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (781 aa)
RFC5Replication factor C subunit 5. (338 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
LOC104871412General transcription factor IIH subunit 2. (395 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
XPADNA repair protein complementing XP-A cells. (262 aa)
COPS8COP9 signalosome complex subunit 8. (209 aa)
GTF2H3General transcription factor IIH subunit 3. (305 aa)
POLKDNA polymerase kappa. (862 aa)
H920_05086B-lymphocyte antigen CD19. (140 aa)
MNAT1CDK-activating kinase assembly factor MAT1. (309 aa)
RPA2Replication protein A 32 kDa subunit. (270 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
CETN3Centrin-3. (231 aa)
XPCDNA repair protein complementing XP-C cells. (925 aa)
SUMO1Small ubiquitin-related modifier. (110 aa)
POLD2DNA polymerase delta subunit 2. (469 aa)
UBA52KxDL motif containing 1. (232 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
COPS4COP9 signalosome complex subunit 4. (406 aa)
MEIOBCDC24_OB3 domain-containing protein. (471 aa)
CCNHCyclin-H; Belongs to the cyclin family. (323 aa)
NFRKBNuclear factor related to kappa-B-binding protein. (1299 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (615 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (614 aa)
GPS1COP9 signalosome complex subunit 1. (490 aa)
RAD23AUV excision repair protein RAD23 like protein A. (362 aa)
RNF111E3 ubiquitin-protein ligase Arkadia; Belongs to the cyclin family. (987 aa)
Mcrs1Microspherule protein 1. (462 aa)
RCBTB2RCC1 and BTB domain-containing protein 2. (551 aa)
Pold3DNA polymerase delta subunit 3. (465 aa)
POLD1DNA polymerase delta 1, catalytic subunit. (933 aa)
ENSFDAP00000019135annotation not available (986 aa)
UbcPolyubiquitin-B. (235 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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