STRINGSTRING
RFC5 RFC5 RFC4 RFC4 DDB1 DDB1 Hmgn2 Hmgn2 ERCC8 ERCC8 POLR2B POLR2B POLE3 POLE3 POLR2F POLR2F Ubc Ubc H920_02502 H920_02502 PRPF19 PRPF19 POLD1 POLD1 Pold3 Pold3 RCBTB2 RCBTB2 POLR2H POLR2H POLR2C POLR2C Polr2a Polr2a H920_04535 H920_04535 LIG1 LIG1 POLE2 POLE2 RPA1 RPA1 CCNH CCNH TCEA1 TCEA1 MEIOB MEIOB UBA52 UBA52 POLR2D POLR2D POLD2 POLD2 POLR2G POLR2G NRDE2 NRDE2 ERCC6 ERCC6 RBX1 RBX1 POLR2L POLR2L USP40 USP40 H920_04177 H920_04177 CDK7 CDK7 H920_05253 H920_05253 GTF2H1 GTF2H1 RPS27A RPS27A H920_16073 H920_16073 POLR2K POLR2K AQR AQR Pold4 Pold4 GTF2H4 GTF2H4 RFC3 RFC3 RPA3 RPA3 ENSFDAP00000011192 ENSFDAP00000011192 RFC2 RFC2 CUL4B CUL4B ERCC2 ERCC2 POLE POLE PPIE PPIE RCBTB1 RCBTB1 H920_00253 H920_00253 RFC1 RFC1 USP7 USP7 TCEANC TCEANC CUL4A CUL4A ATAD5 ATAD5 TCEANC2 TCEANC2 Phf3 Phf3 EP300 EP300 POLR2E POLR2E XAB2 XAB2 LIG3 LIG3 GTF2H5 GTF2H5 Isy1 Isy1 XRCC1 XRCC1 ENSFDAP00000003006 ENSFDAP00000003006 ENSFDAP00000002920 ENSFDAP00000002920 TCEA2 TCEA2 ERCC3 ERCC3 LOC104858675 LOC104858675 Tcea3 Tcea3 POLR2I POLR2I UVSSA UVSSA LOC104871412 LOC104871412 PCNA PCNA GTF2H3 GTF2H3 POLK POLK MNAT1 MNAT1 Polr2j Polr2j RPA2 RPA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFC5Replication factor C subunit 5. (338 aa)
RFC4Replication factor C subunit 4. (333 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
Hmgn2High mobility group nucleosomal binding domain 2. (96 aa)
ERCC8DNA excision repair protein ERCC-8. (395 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1178 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
UbcPolyubiquitin-B. (235 aa)
H920_02502PHD finger protein 3. (349 aa)
PRPF19Pre-mRNA-processing factor 19. (440 aa)
POLD1DNA polymerase delta 1, catalytic subunit. (933 aa)
Pold3DNA polymerase delta subunit 3. (465 aa)
RCBTB2RCC1 and BTB domain-containing protein 2. (551 aa)
POLR2HRNA polymerase II subunit H. (150 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3. (266 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
H920_04535High mobility group nucleosome-binding domain-containing protein 4. (97 aa)
LIG1DNA ligase. (916 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (615 aa)
CCNHCyclin-H; Belongs to the cyclin family. (323 aa)
TCEA1Transcription elongation factor A1. (280 aa)
MEIOBCDC24_OB3 domain-containing protein. (471 aa)
UBA52KxDL motif containing 1. (232 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
POLD2DNA polymerase delta subunit 2. (469 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
NRDE2Uncharacterized protein. (1166 aa)
ERCC6DNA excision repair protein ERCC-6. (1446 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
USP40Ubiquitin carboxyl-terminal hydrolase 40; Belongs to the peptidase C19 family. (1231 aa)
H920_04177SPOC domain-containing protein 1. (559 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
H920_05253Transcription elongation factor A protein 3. (345 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
H920_16073Non-histone chromosomal protein HMG-14. (100 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1493 aa)
Pold4DNA polymerase delta subunit 4. (107 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (406 aa)
RFC3Replication factor C subunit 3. (356 aa)
RPA3Replication protein A 14 kDa subunit. (122 aa)
ENSFDAP00000011192annotation not available (51 aa)
RFC2Replication factor C subunit 2. (316 aa)
CUL4BCullin-4B; Belongs to the cullin family. (888 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit. (760 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (531 aa)
H920_00253High mobility group nucleosome-binding domain-containing protein 4. (100 aa)
RFC1Replication factor C subunit 1. (1141 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1086 aa)
TCEANCTranscription elongation factor A N-terminal and central domain-containing protein. (295 aa)
CUL4ACullin 4A. (594 aa)
ATAD5ATPase family AAA domain-containing protein 5. (1822 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa)
Phf3PHD finger protein 3. (112 aa)
EP300Histone acetyltransferase p300. (2430 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
XAB2XPA binding protein 2. (843 aa)
LIG3DNA ligase. (1016 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
Isy1Pre-mRNA-splicing factor ISY1 like protein. (294 aa)
XRCC1DNA repair protein XRCC1. (628 aa)
ENSFDAP00000003006annotation not available (85 aa)
ENSFDAP00000002920annotation not available (87 aa)
TCEA2Transcription elongation factor A protein 2. (278 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (781 aa)
LOC104858675Uroplakin-3b-like protein. (252 aa)
Tcea3Zinc finger protein 436. (421 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
UVSSAUncharacterized protein. (678 aa)
LOC104871412General transcription factor IIH subunit 2. (395 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
GTF2H3General transcription factor IIH subunit 3. (305 aa)
POLKDNA polymerase kappa. (862 aa)
MNAT1CDK-activating kinase assembly factor MAT1. (309 aa)
Polr2jDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
RPA2Replication protein A 32 kDa subunit. (270 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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