STRINGSTRING
Ubc Ubc UBA52 UBA52 Cenpx Cenpx MEIOB MEIOB PROSER1 PROSER1 RPA1 RPA1 NUTF2 NUTF2 POLN POLN FANCM FANCM RPA2 RPA2 FANCD2 FANCD2 Faap24 Faap24 FANCI FANCI ENSFDAP00000002920 ENSFDAP00000002920 FANCL FANCL ERCC4 ERCC4 WDR48 WDR48 DCLRE1B DCLRE1B UBE2T UBE2T ATRIP ATRIP MUS81 MUS81 FANCG FANCG ENSFDAP00000010315 ENSFDAP00000010315 FANCC FANCC EME2 EME2 RPA3 RPA3 FANCE FANCE ATR ATR ERCC1 ERCC1 EME1 EME1 FANCB FANCB RPS27A RPS27A Cenps Cenps ENSFDAP00000015196 ENSFDAP00000015196 FAN1 FAN1 Usp1 Usp1 ENSFDAP00000016886 ENSFDAP00000016886 Slx1a Slx1a DCLRE1A DCLRE1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UbcPolyubiquitin-B. (235 aa)
UBA52KxDL motif containing 1. (232 aa)
CenpxCentromere protein X. (79 aa)
MEIOBCDC24_OB3 domain-containing protein. (471 aa)
PROSER1DUF4476 domain-containing protein. (915 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (615 aa)
NUTF2Nuclear transport factor 2. (127 aa)
POLNDNA polymerase nu. (825 aa)
FANCMFanconi anemia group M protein. (1984 aa)
RPA2Replication protein A 32 kDa subunit. (270 aa)
FANCD2Fanconi anemia group D2 protein. (1441 aa)
Faap24Fanconi anemia-associated protein of 24 kDa. (119 aa)
FANCIFanconi anemia group I protein. (1373 aa)
ENSFDAP00000002920annotation not available (87 aa)
FANCLE3 ubiquitin-protein ligase FANCL. (356 aa)
ERCC4DNA repair endonuclease XPF. (917 aa)
WDR48WD repeat-containing protein 48. (677 aa)
DCLRE1B5' exonuclease Apollo. (535 aa)
UBE2TUbiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (205 aa)
ATRIPATR-interacting protein. (720 aa)
MUS81Crossover junction endonuclease MUS81. (539 aa)
FANCGFA complementation group G. (575 aa)
ENSFDAP00000010315annotation not available (645 aa)
FANCCFanconi anemia group C protein. (574 aa)
EME2Putative crossover junction endonuclease EME2. (371 aa)
RPA3Replication protein A 14 kDa subunit. (122 aa)
FANCEFanconi anemia group E protein. (542 aa)
ATRSerine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2644 aa)
ERCC1DNA excision repair protein ERCC-1. (298 aa)
EME1Crossover junction endonuclease EME1. (554 aa)
FANCBFanconi anemia group B protein. (715 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
CenpsCentromere protein S. (58 aa)
ENSFDAP00000015196annotation not available (428 aa)
FAN1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1021 aa)
Usp1Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (748 aa)
ENSFDAP00000016886annotation not available (678 aa)
Slx1aSulfotransferase; Belongs to the sulfotransferase 1 family. (63 aa)
DCLRE1ADNA cross-link repair 1A protein. (1034 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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