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| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | RPA2 | Replication protein A 32 kDa subunit. (270 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1. (953 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (405 aa) |
| | PSMA5 | Proteasome 20S subunit alpha 5. (241 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (817 aa) |
| | Mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | RFC5 | Replication factor C subunit 5. (338 aa) |
| | CDC23 | Cell division cycle protein 23 like protein. (597 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (350 aa) |
| | PSMC3 | 26S protease regulatory subunit 6A. (440 aa) |
| | ORC3 | Origin recognition complex subunit 3. (720 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11. (391 aa) |
| | GINS1 | DNA replication complex GINS protein PSF1. (196 aa) |
| | DNA2 | DNA2-like helicase. (1059 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa) |
| | ENSFDAP00000002920 | annotation not available (87 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (506 aa) |
| | FZR1 | Fizzy-related protein like protein. (493 aa) |
| | CDK2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | ANAPC2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (827 aa) |
| | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7. (324 aa) |
| | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (376 aa) |
| | CDC16 | Cell division cycle protein 16 like protein. (626 aa) |
| | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10. (226 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (678 aa) |
| | PSMF1 | Proteasome inhibitor PI31 subunit. (271 aa) |
| | GMNN | Geminin. (208 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5. (755 aa) |
| | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4. (379 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5. (1822 aa) |
| | PSME3 | Proteasome activator complex subunit 3. (265 aa) |
| | CDC26 | Transmembrane protein 71. (84 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (405 aa) |
| | CDT1 | DNA replication factor Cdt1. (542 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | RFC1 | Replication factor C subunit 1. (1141 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | ANAPC1 | Anaphase-promoting complex subunit 1. (1944 aa) |
| | SKP2 | S-phase kinase-associated protein 2. (424 aa) |
| | PSMD2 | Proteasome 26S subunit, non-ATPase 2. (908 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ANAPC7 | Anaphase-promoting complex subunit 7. (592 aa) |
| | Anapc11 | Anaphase-promoting complex subunit 11. (84 aa) |
| | RCBTB1 | RCC1 and BTB domain-containing protein 1. (531 aa) |
| | Tm4sf19 | Transmembrane 4 L6 family member 19. (181 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa) |
| | PSME4 | Proteasome activator subunit 4. (1804 aa) |
| | GINS3 | GINS complex subunit 3. (216 aa) |
| | PSMC6 | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (389 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | PSME2 | Proteasome activator complex subunit 2. (239 aa) |
| | ENSFDAP00000010230 | annotation not available (709 aa) |
| | Fam89b | Family with sequence similarity 89 member B. (93 aa) |
| | POLA1 | DNA polymerase. (1462 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (331 aa) |
| | RFC2 | Replication factor C subunit 2. (316 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (903 aa) |
| | RPA3 | Replication protein A 14 kDa subunit. (122 aa) |
| | PSMB7 | Proteasome subunit beta type-7. (277 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | Fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | PSMC5 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa) |
| | PSMA4 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (210 aa) |
| | H920_07431 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (136 aa) |
| | UBE2S | Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (212 aa) |
| | Pold4 | DNA polymerase delta subunit 4. (107 aa) |
| | ANAPC10 | Anaphase promoting complex subunit 10. (185 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) |
| | RPS27A | Ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | PSMA6 | Proteasome subunit alpha type. (247 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (162 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5. (504 aa) |
| | CCNA2 | Cyclin A2. (400 aa) |
| | H920_20354 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | ANAPC15 | Protein HSPC020 like protein. (133 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (786 aa) |
| | PSMB1 | Proteasome subunit beta. (240 aa) |
| | ENSFDAP00000015944 | annotation not available (350 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (487 aa) |
| | ANAPC16 | Anaphase-promoting complex subunit 16. (110 aa) |
| | RFC4 | Replication factor C subunit 4. (333 aa) |
| | Mcm8 | DNA replication licensing factor MCM8; Belongs to the MCM family. (833 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | PSMB9 | Proteasome subunit beta type-9. (219 aa) |
| | CCNA1 | Cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | UBE2E1 | Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | CDC27 | Cell division cycle 27. (825 aa) |
| | H920_15675 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (135 aa) |
| | POLE3 | DNA polymerase epsilon subunit 3. (147 aa) |
| | H920_01229 | Cullin-1; Belongs to the cullin family. (265 aa) |
| | Prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa) |
| | Ubc | Polyubiquitin-B. (235 aa) |
| | Psmd9 | 26S proteasome non-ATPase regulatory subunit 9. (223 aa) |
| | CDK3 | Cyclin dependent kinase 3. (297 aa) |
| | POLD1 | DNA polymerase delta 1, catalytic subunit. (933 aa) |
| | Pold3 | DNA polymerase delta subunit 3. (465 aa) |
| | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6. (340 aa) |
| | MCM9 | DNA replication licensing factor MCM9; Belongs to the MCM family. (1106 aa) |
| | PSME1 | Proteasome activator complex subunit 1. (249 aa) |
| | RCBTB2 | RCC1 and BTB domain-containing protein 2. (551 aa) |
| | CUL1 | Cullin-1; Belongs to the cullin family. (776 aa) |
| | PSMC1 | 26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa) |
| | UBE2C | Ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | LIG1 | DNA ligase. (916 aa) |
| | PSMA1 | Proteasome subunit alpha type-1. (264 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (615 aa) |
| | MEIOB | CDC24_OB3 domain-containing protein. (471 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (216 aa) |
| | UBA52 | KxDL motif containing 1. (232 aa) |
| | ORC2 | Origin recognition complex subunit 2. (599 aa) |
| | POLD2 | DNA polymerase delta subunit 2. (469 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (188 aa) |
| | Pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12. (456 aa) |
| | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) |
| | PSMC4 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) |
| | PSMC2 | 26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (464 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (108 aa) |
