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PSMD5 PSMD5 H920_00437 H920_00437 COP1 COP1 PSMD3 PSMD3 MDM4 MDM4 ZNF385B ZNF385B PSMC2 PSMC2 PSMC4 PSMC4 PSMD12 PSMD12 PSMA3 PSMA3 UBA52 UBA52 PSMA7 PSMA7 CDKN1B CDKN1B Mdm2 Mdm2 PSMA1 PSMA1 PSMC1 PSMC1 PSME1 PSME1 PSMD6 PSMD6 Cdkn1c Cdkn1c CDK3 CDK3 Psmd9 Psmd9 Ubc Ubc CHEK2 CHEK2 CCNA1 CCNA1 PSMB9 PSMB9 PHF20 PHF20 PSMB1 PSMB1 PSMB5 PSMB5 CCNA2 CCNA2 ZNF385A ZNF385A PSMB10 PSMB10 PSMA6 PSMA6 RPS27A RPS27A PSMA2 PSMA2 PSMD14 PSMD14 ATM ATM PSMA4 PSMA4 PSMC5 PSMC5 PSMA8 PSMA8 ENSFDAP00000011804 ENSFDAP00000011804 TP53 TP53 PSMB7 PSMB7 PSMD1 PSMD1 CCNE2 CCNE2 PSMA5 PSMA5 CHEK1 CHEK1 PSMD8 PSMD8 PSMC3 PSMC3 PSMB6 PSMB6 PSMD11 PSMD11 CDKN1A CDKN1A ENSFDAP00000002920 ENSFDAP00000002920 CDK2 CDK2 PSMD7 PSMD7 PSMD13 PSMD13 PSMD10 PSMD10 PSMF1 PSMF1 PSMD4 PSMD4 PSMB4 PSMB4 PSME3 PSME3 CCNE1 CCNE1 PSMB3 PSMB3 PSMD2 PSMD2 PSMB2 PSMB2 PSME4 PSME4 PSMC6 PSMC6 PSME2 PSME2 ZNF385C ZNF385C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
H920_00437Zinc finger protein 385B. (66 aa)
COP1E3 ubiquitin-protein ligase RFWD2. (631 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (331 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (492 aa)
ZNF385BZinc finger protein 385B. (477 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (464 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
UBA52KxDL motif containing 1. (232 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2. (504 aa)
PSMA1Proteasome subunit alpha type-1. (264 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (340 aa)
Cdkn1cCyclin-dependent kinase inhibitor 1C. (127 aa)
CDK3Cyclin dependent kinase 3. (297 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (223 aa)
UbcPolyubiquitin-B. (235 aa)
CHEK2Serine/threonine-protein kinase Chk2. (549 aa)
CCNA1Cyclin-A1; Belongs to the cyclin family. (421 aa)
PSMB9Proteasome subunit beta type-9. (219 aa)
PHF20PHD finger protein 20. (1008 aa)
PSMB1Proteasome subunit beta. (240 aa)
PSMB5Proteasome subunit beta. (263 aa)
CCNA2Cyclin A2. (400 aa)
ZNF385AZinc finger protein 385A. (382 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMA6Proteasome subunit alpha type. (247 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3061 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (210 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ENSFDAP00000011804annotation not available (202 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
PSMB7Proteasome subunit beta type-7. (277 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1. (953 aa)
CCNE2G1/S-specific cyclin-E2; Belongs to the cyclin family. (405 aa)
PSMA5Proteasome 20S subunit alpha 5. (241 aa)
CHEK1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (350 aa)
PSMC326S protease regulatory subunit 6A. (440 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (391 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (165 aa)
ENSFDAP00000002920annotation not available (87 aa)
CDK2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
PSMF1Proteasome inhibitor PI31 subunit. (271 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (379 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
PSME3Proteasome activator complex subunit 3. (265 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (405 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD2Proteasome 26S subunit, non-ATPase 2. (908 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSME4Proteasome activator subunit 4. (1804 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (389 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
ZNF385CZinc finger protein 385C. (380 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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