STRINGSTRING
ARHGEF10 ARHGEF10 H920_15109 H920_15109 TRAF2 TRAF2 TAB1 TAB1 ARHGEF7 ARHGEF7 ARHGEF5 ARHGEF5 NCSTN NCSTN Map3k20 Map3k20 Tnfrsf10b Tnfrsf10b ARHGDIA ARHGDIA FADD FADD Rnf31 Rnf31 RBCK1 RBCK1 ITGB3BP ITGB3BP YWHAE YWHAE Gsap Gsap Arhgef18 Arhgef18 RIPK1 RIPK1 ITSN1 ITSN1 ENSFDAP00000010206 ENSFDAP00000010206 MCF2L MCF2L PSEN2 PSEN2 WDR31 WDR31 LOC104862966 LOC104862966 NFATC4 NFATC4 Casp3 Casp3 NGF NGF NSMAF NSMAF NET1 NET1 LOC104856727 LOC104856727 ARHGEF37 ARHGEF37 SOS2 SOS2 VAV2 VAV2 MYD88 MYD88 CFLAR CFLAR FGD3 FGD3 OTULIN OTULIN ENSFDAP00000007247 ENSFDAP00000007247 H920_12778 H920_12778 ARHGEF3 ARHGEF3 ARHGEF9 ARHGEF9 TNFSF10 TNFSF10 LINGO1 LINGO1 VAV1 VAV1 SOS1 SOS1 CLIP3 CLIP3 MADD MADD NGFR NGFR ENSFDAP00000005475 ENSFDAP00000005475 BAD BAD STUB1 STUB1 SESTD1 SESTD1 TRADD TRADD MCF2 MCF2 Fas Fas ARHGEF26 ARHGEF26 RAC1 RAC1 TAX1BP1 TAX1BP1 SPATA2 SPATA2 MAPK8 MAPK8 TNF TNF CLIP4 CLIP4 USP2 USP2 BIRC3 BIRC3 Rtn4 Rtn4 ADAM17 ADAM17 ENSFDAP00000003729 ENSFDAP00000003729 OTULINL OTULINL ARHGEF4 ARHGEF4 AATF AATF GNA13 GNA13 VAV3 VAV3 OMG OMG ENSFDAP00000002920 ENSFDAP00000002920 ARHGEF10L ARHGEF10L OPTN OPTN ARHGEF2 ARHGEF2 IKBKB IKBKB IRAK1 IRAK1 ARHGEF15 ARHGEF15 MAPKAPK2 MAPKAPK2 TMEM198 TMEM198 OTUD7B OTUD7B Ikbke Ikbke TAB2 TAB2 TRAF1 TRAF1 Arhgef33 Arhgef33 UBE2D1 UBE2D1 BIRC2 BIRC2 RHOA RHOA ARHGEF40 ARHGEF40 RTN4R RTN4R UBA52 UBA52 TAB3 TAB3 UBE2D2 UBE2D2 BEX3 BEX3 H920_09942 H920_09942 CASP2 CASP2 IKBKG IKBKG NGEF NGEF SMPD3 SMPD3 CYLD CYLD SHARPIN SHARPIN RACK1 RACK1 KALRN KALRN ABR ABR TRIO TRIO ULK1 ULK1 APH1A APH1A TNFAIP3 TNFAIP3 USP21 USP21 RIPK2 RIPK2 ARHGEF16 ARHGEF16 ARHGEF11 ARHGEF11 BCL2L11 BCL2L11 USP4 USP4 TGM6 TGM6 ARHGEF39 ARHGEF39 Tgm3 Tgm3 ENSFDAP00000018414 ENSFDAP00000018414 Ubc Ubc APH1B APH1B XIAP XIAP TBK1 TBK1 NFKB1 NFKB1 LOC104876601 LOC104876601 PRDM4 PRDM4 SQSTM1 SQSTM1 LOC104867783 LOC104867783 ENSFDAP00000017172 ENSFDAP00000017172 MAG MAG PSENEN PSENEN ECT2 ECT2 CASP8 CASP8 Chuk Chuk PSEN1 PSEN1 SPPL2A SPPL2A ARHGEF1 ARHGEF1 PLEKHG5 PLEKHG5 ULK2 ULK2 Arhgef25 Arhgef25 NFKBIA NFKBIA BAG4 BAG4 SPPL2C SPPL2C ARHGEF17 ARHGEF17 TRAF6 TRAF6 MAP3K7 MAP3K7 FGD1 FGD1 SPPL2B SPPL2B FGD4 FGD4 RPS27A RPS27A ARHGEF12 ARHGEF12 ENSFDAP00000013841 ENSFDAP00000013841 TIAM1 TIAM1 Faslg Faslg LINGO2 LINGO2 Akap13 Akap13 ARHGEF6 ARHGEF6 Arhgef19 Arhgef19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARHGEF10Rho guanine nucleotide exchange factor 10. (1325 aa)
H920_15109CAP-Gly domain-containing linker protein 1. (365 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (809 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1372 aa)
NCSTNNicastrin. (709 aa)
Map3k20Mitogen-activated protein kinase kinase kinase MLT. (671 aa)
Tnfrsf10bTumor necrosis factor receptor superfamily member 10B. (417 aa)
ARHGDIARho GDP-dissociation inhibitor 1. (204 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
Rnf31RING finger protein 31. (1069 aa)
RBCK1RanBP-type and C3HC4-type zinc finger-containing protein 1. (510 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (180 aa)
YWHAE14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
GsapGamma-secretase-activating protein. (175 aa)
Arhgef18Rho guanine nucleotide exchange factor 18. (788 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (660 aa)
ITSN1Intersectin-1. (1716 aa)
ENSFDAP00000010206annotation not available (133 aa)
MCF2LGuanine nucleotide exchange factor DBS. (1121 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
WDR31WD repeat-containing protein 31. (366 aa)
LOC104862966T-lymphoma invasion and metastasis-inducing protein 2. (916 aa)
NFATC4Nuclear factor of activated T-cells, cytoplasmic 4. (868 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (305 aa)
NSMAFProtein FAN. (902 aa)
NET1Neuroepithelial cell-transforming gene 1 protein. (553 aa)
LOC104856727Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ARHGEF37Rho guanine nucleotide exchange factor 37. (674 aa)
SOS2Son of sevenless like protein 2. (1310 aa)
VAV2Guanine nucleotide exchange factor VAV2. (771 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (435 aa)
FGD3FYVE, RhoGEF and PH domain-containing protein 3. (736 aa)
OTULINProtein FAM105B. (301 aa)
ENSFDAP00000007247annotation not available (119 aa)
H920_12778Dynamin-binding protein. (219 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (558 aa)
ARHGEF9Rho guanine nucleotide exchange factor 9. (512 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (289 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (620 aa)
VAV1Proto-oncogene vav. (714 aa)
SOS1Son of sevenless like protein 1. (1289 aa)
CLIP3CAP-Gly domain-containing linker protein 3. (547 aa)
MADDMAP kinase activating death domain. (1595 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (362 aa)
ENSFDAP00000005475annotation not available (139 aa)
BADBcl2 antagonist of cell death. (162 aa)
STUB1STIP1 homology and U box-containing protein 1. (250 aa)
SESTD1SEC14 domain and spectrin repeat-containing protein 1. (696 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (310 aa)
MCF2Proto-oncogene DBL. (1010 aa)
FasTumor necrosis factor receptor superfamily member 6. (290 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (869 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (199 aa)
TAX1BP1Tax1-binding protein 1 like protein. (839 aa)
SPATA2Spermatogenesis-associated protein 2. (514 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
CLIP4CAP-Gly domain containing linker protein family member 4. (702 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (612 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (644 aa)
Rtn4Reticulon. (199 aa)
ADAM17Disintegrin and metalloproteinase domain-containing protein 17. (836 aa)
ENSFDAP00000003729annotation not available (135 aa)
OTULINLProtein FAM105A. (284 aa)
ARHGEF4Rho guanine nucleotide exchange factor 4. (484 aa)
AATFProtein AATF. (494 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (373 aa)
VAV3Guanine nucleotide exchange factor VAV3. (779 aa)
OMGOligodendrocyte myelin glycoprotein. (443 aa)
ENSFDAP00000002920annotation not available (87 aa)
ARHGEF10LRho guanine nucleotide exchange factor 10-like protein. (1222 aa)
OPTNOptineurin. (599 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (957 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (453 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (845 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (399 aa)
TMEM198Transmembrane protein 198. (360 aa)
OTUD7BOTU domain-containing protein 7B. (843 aa)
IkbkeInhibitor of nuclear factor kappa-B kinase subunit epsilon. (130 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
TRAF1TNF receptor-associated factor. (415 aa)
Arhgef33Rho guanine nucleotide exchange factor 33. (720 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (618 aa)
RHOATransforming protein RhoA. (193 aa)
ARHGEF40Rho guanine nucleotide exchange factor 40. (1517 aa)
RTN4RReticulon 4 receptor. (465 aa)
UBA52KxDL motif containing 1. (232 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D4; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
BEX3Protein BEX3. (111 aa)
H920_09942Sphingomyelin phosphodiesterase 2. (90 aa)
CASP2Caspase-2; Belongs to the peptidase C14A family. (452 aa)
IKBKGNF-kappa-B essential modulator. (417 aa)
NGEFEphexin-1. (703 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (569 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (951 aa)
SHARPINSharpin. (414 aa)
RACK1Guanine nucleotide-binding protein subunit beta-2-like 1. (317 aa)
KALRNKalirin. (2971 aa)
ABRActive breakpoint cluster region-related protein. (853 aa)
TRIOTriple functional domain protein. (3024 aa)
ULK1Serine/threonine-protein kinase ULK1. (1043 aa)
APH1AGamma-secretase subunit APH-1A. (265 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (755 aa)
USP21Ubiquitin carboxyl-terminal hydrolase 21; Belongs to the peptidase C19 family. (565 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (482 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (707 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1534 aa)
BCL2L11BCL2 like 11. (195 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (964 aa)
TGM6Protein-glutamine gamma-glutamyltransferase 6. (706 aa)
ARHGEF39Uncharacterized protein. (335 aa)
Tgm3Protein-glutamine gamma-glutamyltransferase E. (695 aa)
ENSFDAP00000018414annotation not available (666 aa)
UbcPolyubiquitin-B. (235 aa)
APH1BGamma-secretase subunit APH-1B. (257 aa)
XIAPBaculoviral IAP repeat-containing protein 4. (497 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (894 aa)
LOC104876601Transmembrane protein 198-B. (350 aa)
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (807 aa)
SQSTM1Sequestosome-1. (400 aa)
LOC104867783Rho guanine nucleotide exchange factor 19. (55 aa)
ENSFDAP00000017172annotation not available (132 aa)
MAGMyelin-associated glycoprotein. (626 aa)
PSENENGamma-secretase subunit PEN-2. (101 aa)
ECT2Protein ECT2. (914 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (462 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
SPPL2ASignal peptide peptidase like 2A. (499 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (943 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1028 aa)
ULK2Serine/threonine-protein kinase ULK2. (1057 aa)
Arhgef25Rho guanine nucleotide exchange factor 25. (618 aa)
NFKBIANF-kappa-B inhibitor alpha. (224 aa)
BAG4BAG family molecular chaperone regulator 4. (441 aa)
SPPL2CSignal peptide peptidase-like 2C. (552 aa)
ARHGEF17Rho guanine nucleotide exchange factor 17. (1835 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (606 aa)
FGD1FYVE, RhoGEF and PH domain-containing protein 1. (934 aa)
SPPL2BSignal peptide peptidase-like 2B. (583 aa)
FGD4FYVE, RhoGEF and PH domain-containing protein 4. (769 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1543 aa)
ENSFDAP00000013841annotation not available (257 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1. (1590 aa)
FaslgTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (69 aa)
LINGO2Leucine rich repeat and Ig domain containing 2. (606 aa)
Akap13A-kinase anchor protein 13. (1430 aa)
ARHGEF6Rho guanine nucleotide exchange factor 6. (789 aa)
Arhgef19Rho guanine nucleotide exchange factor 19. (423 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
Server load: low (22%) [HD]