STRINGSTRING
TFRC TFRC SYT11 SYT11 HGS HGS COPS5 COPS5 ZFYVE1 ZFYVE1 APOB APOB H920_08701 H920_08701 GRB2 GRB2 SYT1 SYT1 SH3GL2 SH3GL2 TOR1B TOR1B EGFR EGFR PPP1R42 PPP1R42 CLPB CLPB CBL CBL BTC BTC FCHO1 FCHO1 KIAA0319 KIAA0319 ENSFDAP00000002920 ENSFDAP00000002920 ZFYVE19 ZFYVE19 AAK1 AAK1 EGF EGF AVPR2 AVPR2 CD3D CD3D VAMP8 VAMP8 FCHO2 FCHO2 VAMP7 VAMP7 KIAA0319L KIAA0319L Epn1 Epn1 AGFG2 AGFG2 STAM STAM PICALM PICALM UBL7 UBL7 Tgoln2 Tgoln2 UBQLN3 UBQLN3 REPS1 REPS1 NECAP1 NECAP1 SYT4 SYT4 COPS8 COPS8 EPS15L1 EPS15L1 MCTP1 MCTP1 DVL2 DVL2 M6PR M6PR UBA52 UBA52 COPS4 COPS4 CFTR CFTR AP2A2 AP2A2 STON2 STON2 CLTA CLTA BMP2K BMP2K EPGN EPGN GPS1 GPS1 ITSN2 ITSN2 CLTCL1 CLTCL1 UBQLN4 UBQLN4 Ston1 Ston1 REPS2 REPS2 SNAP91 SNAP91 ARRB1 ARRB1 GRK2 GRK2 SYT8 SYT8 AP2M1 AP2M1 Ubc Ubc EPS15 EPS15 NECAP2 NECAP2 DAB2 DAB2 WNT5A WNT5A VAMP3 VAMP3 Ubqln1 Ubqln1 H920_03666 H920_03666 TGFA TGFA ENSFDAP00000016887 ENSFDAP00000016887 IL7R IL7R TACR1 TACR1 STAM2 STAM2 LDLR LDLR SGIP1 SGIP1 COPS2 COPS2 IGF2R IGF2R MCTP2 MCTP2 Ap2b1 Ap2b1 RPS27A RPS27A FZD4 FZD4 VAMP4 VAMP4 CHRM2 CHRM2 GPR52 GPR52 EREG EREG H920_07302 H920_07302 TOR1A TOR1A SLC2A8 SLC2A8 LOC104860973 LOC104860973 H920_14239 H920_14239 ENSFDAP00000012053 ENSFDAP00000012053 Vamp2 Vamp2 LOC104857908 LOC104857908 H920_10388 H920_10388 CLTB CLTB Sh3kbp1 Sh3kbp1 CLTC CLTC NETO1 NETO1 HBEGF HBEGF SH3GL3 SH3GL3 AREG AREG LDLRAP1 LDLRAP1 AP2S1 AP2S1 ITSN1 ITSN1 COPS3 COPS3 ENTHD1 ENTHD1 LRP2 LRP2 LOC104870588 LOC104870588 CD3G CD3G AGTR1 AGTR1 VAMP5 VAMP5 TF TF SH3GL1 SH3GL1 SYT2 SYT2 LMBRD2 LMBRD2 ARRB2 ARRB2 LOC104862948 LOC104862948 EPN2 EPN2 CLHC1 CLHC1 AP2A1 AP2A1 SCARB2 SCARB2 COPS6 COPS6 NETO2 NETO2 GRK3 GRK3 LOC104863160 LOC104863160 COPS7B COPS7B SYT9 SYT9 COPS7A COPS7A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TFRCTransferrin receptor protein 1. (765 aa)
SYT11Synaptotagmin-11. (431 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate. (778 aa)
COPS5COP9 signalosome complex subunit 5. (334 aa)
ZFYVE1Zinc finger FYVE domain-containing protein 1. (777 aa)
APOBApolipoprotein B-100. (4381 aa)
H920_08701Arrestin-C. (108 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
SYT1Synaptotagmin-1. (422 aa)
SH3GL2Endophilin-A1. (349 aa)
TOR1BTorsin-1B. (269 aa)
EGFRReceptor protein-tyrosine kinase. (1168 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (302 aa)
CLPBCaseinolytic peptidase B protein like protein. (706 aa)
CBLE3 ubiquitin-protein ligase CBL. (851 aa)
BTCProbetacellulin. (179 aa)
FCHO1FCH and mu domain containing endocytic adaptor 1. (736 aa)
KIAA0319Dyslexia-associated protein KIAA0319. (1123 aa)
ENSFDAP00000002920annotation not available (87 aa)
ZFYVE19Zinc finger FYVE domain-containing protein 19. (403 aa)
AAK1AP2-associated protein kinase 1. (965 aa)
EGFPro-epidermal growth factor. (1155 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (366 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (166 aa)
VAMP8Vesicle-associated membrane protein 8. (101 aa)
FCHO2FCH domain only protein 2. (796 aa)
VAMP7Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
KIAA0319LDyslexia-associated protein KIAA0319-like protein. (1077 aa)
Epn1Epsin 1. (54 aa)
AGFG2Arf-GAP domain and FG repeats-containing protein 2. (451 aa)
STAMSignal transducing adapter molecule 1. (542 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein. (660 aa)
UBL7Ubiquitin-like protein 7. (380 aa)
Tgoln2Trans-Golgi network integral membrane protein 2. (499 aa)
UBQLN3Ubiquilin-3. (651 aa)
REPS1RalBP1-associated Eps domain-containing protein 1. (744 aa)
NECAP1Adaptin ear-binding coat-associated protein 1. (269 aa)
SYT4Synaptotagmin-4. (425 aa)
COPS8COP9 signalosome complex subunit 8. (209 aa)
EPS15L1Epidermal growth factor receptor substrate 15-like 1. (795 aa)
MCTP1Multiple C2 and transmembrane domain-containing protein 1. (777 aa)
DVL2Segment polarity protein dishevelled like protein DVL-2. (736 aa)
M6PRCation-dependent mannose-6-phosphate receptor. (278 aa)
UBA52KxDL motif containing 1. (232 aa)
COPS4COP9 signalosome complex subunit 4. (406 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (928 aa)
STON2Stonin-2; Belongs to the Stoned B family. (894 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
BMP2KBMP-2-inducible protein kinase. (1074 aa)
EPGNEpithelial mitogen. (152 aa)
GPS1COP9 signalosome complex subunit 1. (490 aa)
ITSN2Intersectin-2. (1602 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1263 aa)
UBQLN4Ubiquilin-4. (558 aa)
Ston1Stonin-1; Belongs to the Stoned B family. (753 aa)
REPS2RalBP1-associated Eps domain-containing protein 2. (602 aa)
SNAP91Clathrin coat assembly protein AP180. (906 aa)
ARRB1Beta-arrestin-1. (418 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (686 aa)
SYT8Synaptotagmin-8. (387 aa)
AP2M1AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (435 aa)
UbcPolyubiquitin-B. (235 aa)
EPS15Epidermal growth factor receptor substrate 15. (926 aa)
NECAP2NECAP endocytosis associated 2. (268 aa)
DAB2Disabled like protein 2. (769 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
VAMP3Vesicle-associated membrane protein 3. (99 aa)
Ubqln1Ubiquilin-1. (529 aa)
H920_03666Epsin-3. (316 aa)
TGFAProtransforming growth factor alpha. (157 aa)
ENSFDAP00000016887annotation not available (781 aa)
IL7RSperm flagellar protein 2. (457 aa)
TACR1Substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
STAM2Signal transducing adapter molecule 2. (524 aa)
LDLRLow-density lipoprotein receptor. (779 aa)
SGIP1SH3-containing GRB2-like protein 3-interacting protein 1. (828 aa)
COPS2COP9 signalosome complex subunit 2. (443 aa)
IGF2RCation-independent mannose-6-phosphate receptor. (2408 aa)
MCTP2Multiple C2 and transmembrane domain-containing protein 2. (876 aa)
Ap2b1AP complex subunit beta. (951 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
VAMP4Vesicle-associated membrane protein 4. (141 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
GPR52G protein-coupled receptor 52. (361 aa)
EREGProepiregulin. (163 aa)
H920_07302Ubiquilin-1. (487 aa)
TOR1AUncharacterized protein. (272 aa)
SLC2A8Solute carrier family 2, facilitated glucose transporter member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (357 aa)
LOC104860973Low-density lipoprotein receptor-related protein 2. (2025 aa)
H920_14239SH3 domain-containing kinase-binding protein 1. (113 aa)
ENSFDAP00000012053annotation not available (81 aa)
Vamp2Vesicle associated membrane protein 2. (146 aa)
LOC104857908Ubiquilin-1. (489 aa)
H920_10388NEDD8. (81 aa)
CLTBClathrin light chain B. (211 aa)
Sh3kbp1SH3 domain containing kinase binding protein 1. (709 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
NETO1Neuropilin and tolloid like 1. (530 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
SH3GL3Endophilin-A3. (312 aa)
AREGAmphiregulin. (242 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (278 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (185 aa)
ITSN1Intersectin-1. (1716 aa)
COPS3COP9 signalosome complex subunit 3. (423 aa)
ENTHD1ENTH domain-containing protein 1. (597 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4630 aa)
LOC104870588NEDD8. (78 aa)
CD3GCD3g molecule. (182 aa)
AGTR1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
VAMP5Vesicle-associated membrane protein 5. (85 aa)
TFSerotransferrin. (695 aa)
SH3GL1Endophilin-A2. (340 aa)
SYT2Synaptotagmin-2. (423 aa)
LMBRD2LMBR1 domain-containing protein 2. (694 aa)
ARRB2Beta-arrestin-2. (409 aa)
LOC104862948Phosphatidylinositol-binding clathrin assembly protein. (406 aa)
EPN2Epsin-2. (646 aa)
CLHC1TSNAXIP1_N domain-containing protein. (591 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (976 aa)
SCARB2Lysosome membrane protein 2; Belongs to the CD36 family. (478 aa)
COPS6COP9 signalosome complex subunit 6. (347 aa)
NETO2Neuropilin and tolloid-like protein 2. (518 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (646 aa)
LOC104863160Inhibitor of carbonic anhydrase; Belongs to the transferrin family. (700 aa)
COPS7BCOP9 signalosome complex subunit 7b. (264 aa)
SYT9Synaptotagmin-9. (442 aa)
COPS7ACOP9 signalosome complex subunit 7a. (277 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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