STRINGSTRING
MAML1 MAML1 PSME2 PSME2 MAML3 MAML3 FNDC3B FNDC3B PSMC6 PSMC6 KAT2B KAT2B Mamld1 Mamld1 RUNX3 RUNX3 TCF7L2 TCF7L2 PSMB2 PSMB2 PSMD2 PSMD2 NINJ2 NINJ2 RBPJL RBPJL PSMB3 PSMB3 TCF7 TCF7 ZFHX3 ZFHX3 SMURF2 SMURF2 TEAD1 TEAD1 PSME3 PSME3 PSMB4 PSMB4 EP300 EP300 PSMD4 PSMD4 NOTCH1 NOTCH1 SMAD3 SMAD3 PSMF1 PSMF1 PSMD10 PSMD10 CREBZF CREBZF PSMD13 PSMD13 PSMD7 PSMD7 TEAD2 TEAD2 TEAD4 TEAD4 ENSFDAP00000002920 ENSFDAP00000002920 RUNX1 RUNX1 CDKN1A CDKN1A PSMD11 PSMD11 HES1 HES1 PSMB6 PSMB6 PSMC3 PSMC3 PSMD8 PSMD8 CCND1 CCND1 PSMA5 PSMA5 PSMD1 PSMD1 PSMC2 PSMC2 PSMC4 PSMC4 PSMD12 PSMD12 ZFHX2 ZFHX2 PSMA3 PSMA3 UBA52 UBA52 PSMA7 PSMA7 Mdm2 Mdm2 PSMA1 PSMA1 TGFB1 TGFB1 SMAD4 SMAD4 FNDC3A FNDC3A PSMC1 PSMC1 PSME1 PSME1 PSMD6 PSMD6 Ctnnb1 Ctnnb1 Psmd9 Psmd9 Ubc Ubc SMURF1 SMURF1 PSMB9 PSMB9 BRD2 BRD2 PSMB1 PSMB1 PSMB5 PSMB5 PSMD5 PSMD5 PSMB10 PSMB10 ENSFDAP00000014687 ENSFDAP00000014687 PSMA6 PSMA6 TCF7L1 TCF7L1 MAML2 MAML2 RPS27A RPS27A PSMA2 PSMA2 PSMD14 PSMD14 HDAC4 HDAC4 H920_09656 H920_09656 PSMA4 PSMA4 PSMC5 PSMC5 LEF1 LEF1 ENSFDAP00000011804 ENSFDAP00000011804 TP53 TP53 PSMB7 PSMB7 PSMD3 PSMD3 ZFHX4 ZFHX4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAML1Mastermind-like protein 1. (849 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
MAML3Mastermind-like protein 3. (1130 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (389 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (731 aa)
Mamld1Mastermind-like domain-containing protein 1. (747 aa)
RUNX3Runt-related transcription factor 3. (302 aa)
TCF7L2Transcription factor 7 like 2. (413 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD2Proteasome 26S subunit, non-ATPase 2. (908 aa)
NINJ2Ninjurin-2. (145 aa)
RBPJLRecombining binding protein suppressor of hairless-like protein. (426 aa)
PSMB3Proteasome subunit beta. (205 aa)
TCF7Transcription factor 7. (302 aa)
ZFHX3Zinc finger homeobox protein 3. (3651 aa)
SMURF2E3 ubiquitin-protein ligase. (742 aa)
TEAD1Transcriptional enhancer factor TEF-1. (436 aa)
PSME3Proteasome activator complex subunit 3. (265 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
EP300Histone acetyltransferase p300. (2430 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (379 aa)
NOTCH1Uncharacterized protein. (2309 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
PSMF1Proteasome inhibitor PI31 subunit. (271 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
CREBZFCREB/ATF bZIP transcription factor. (307 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
TEAD2Transcriptional enhancer factor TEF-4. (447 aa)
TEAD4Transcriptional enhancer factor TEF-3. (427 aa)
ENSFDAP00000002920annotation not available (87 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (401 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (165 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (391 aa)
HES1Transcription factor HES-1. (278 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMC326S protease regulatory subunit 6A. (440 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (350 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
PSMA5Proteasome 20S subunit alpha 5. (241 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1. (953 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (464 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
ZFHX2Zinc finger homeobox protein 2. (2573 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
UBA52KxDL motif containing 1. (232 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2. (504 aa)
PSMA1Proteasome subunit alpha type-1. (264 aa)
TGFB1Transforming growth factor beta-1. (333 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1198 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (340 aa)
Ctnnb1Catenin beta-1. (781 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (223 aa)
UbcPolyubiquitin-B. (235 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (744 aa)
PSMB9Proteasome subunit beta type-9. (219 aa)
BRD2Bromodomain-containing protein 2. (799 aa)
PSMB1Proteasome subunit beta. (240 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMB10Proteasome subunit beta. (273 aa)
ENSFDAP00000014687annotation not available (76 aa)
PSMA6Proteasome subunit alpha type. (247 aa)
TCF7L1Transcription factor 7-like 1. (453 aa)
MAML2Mastermind-like protein 2. (989 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1084 aa)
H920_09656Catenin beta-1. (83 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (210 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
LEF1Lymphoid enhancer-binding factor 1. (329 aa)
ENSFDAP00000011804annotation not available (202 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
PSMB7Proteasome subunit beta type-7. (277 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (331 aa)
ZFHX4Zinc finger homeobox protein 4. (3618 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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