STRINGSTRING
ENSFDAP00000015888 ENSFDAP00000015888 ITGB1 ITGB1 ACVR1 ACVR1 RHOA RHOA PARD3B PARD3B UBE2D1 UBE2D1 INHBA INHBA PMEPA1 PMEPA1 BAMBI BAMBI ENSFDAP00000002920 ENSFDAP00000002920 TGFB2 TGFB2 TGFBR2 TGFBR2 RBL1 RBL1 SNW1 SNW1 F11R F11R STUB1 STUB1 SMAD3 SMAD3 SMAD1 SMAD1 ENSFDAP00000005475 ENSFDAP00000005475 ACVRL1 ACVRL1 JUNB JUNB FST FST BMP2 BMP2 ACVR2B ACVR2B PPM1A PPM1A FBN1 FBN1 ITGB8 ITGB8 SMAD2 SMAD2 PCSK4 PCSK4 AMHR2 AMHR2 DRAP1 DRAP1 RPS27A RPS27A ACVR2A ACVR2A PARD6A PARD6A H920_16943 H920_16943 CCNC CCNC CCNK CCNK SKI SKI BMPR1A BMPR1A CHRDL1 CHRDL1 SMURF2 SMURF2 CER1 CER1 ENSFDAP00000007247 ENSFDAP00000007247 ITGAV ITGAV PARD3 PARD3 FSTL1 FSTL1 SMAD5 SMAD5 TGIF2 TGIF2 CDK9 CDK9 STRAP STRAP ENSFDAP00000012053 ENSFDAP00000012053 ATP1B4 ATP1B4 H920_10388 H920_10388 Arhgef18 Arhgef18 BMP10 BMP10 LOC104870588 LOC104870588 SMAD7 SMAD7 Ube2m Ube2m PARP1 PARP1 INHBB INHBB SP1 SP1 Fkbp1a Fkbp1a IRX6 IRX6 MEIS3 MEIS3 Smad9 Smad9 BMPR1B BMPR1B CCNT1 CCNT1 IRX4 IRX4 NCOR2 NCOR2 Cgn Cgn CBL CBL ITGB5 ITGB5 TGFB3 TGFB3 MTMR4 MTMR4 NEDD4L NEDD4L E2F5 E2F5 TGFBR1 TGFBR1 LTBP3 LTBP3 CCNT2 CCNT2 FSTL3 FSTL3 LTBP2 LTBP2 ACVR1C ACVR1C Zfyve16 Zfyve16 GREM2 GREM2 CHRDL2 CHRDL2 E2F4 E2F4 Itgb3 Itgb3 ENSFDAP00000016282 ENSFDAP00000016282 LTBP1 LTBP1 ACVR1B ACVR1B TRIM33 TRIM33 ENSFDAP00000017336 ENSFDAP00000017336 GDF2 GDF2 SMURF1 SMURF1 MKX MKX Ubc Ubc FOXH1 FOXH1 CDK8 CDK8 Tfdp2 Tfdp2 MEN1 MEN1 MAPK3 MAPK3 LTBP4 LTBP4 ZFYVE9 ZFYVE9 RNF111 RNF111 MAPK1 MAPK1 ITGA8 ITGA8 Tgif1 Tgif1 HDAC1 HDAC1 TFDP1 TFDP1 SMAD4 SMAD4 USP9X USP9X TGFB1 TGFB1 CCNQ CCNQ BMPR2 BMPR2 ITGB6 ITGB6 NCOR1 NCOR1 Amh Amh SKIL SKIL UBA52 UBA52 FURIN FURIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSFDAP00000015888annotation not available (251 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (803 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
RHOATransforming protein RhoA. (193 aa)
PARD3BPartitioning defective 3 like protein B. (1166 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
INHBAInhibin beta A chain. (424 aa)
PMEPA1Transmembrane prostate androgen-induced protein. (234 aa)
BAMBIBMP and activin membrane-bound inhibitor like protein. (235 aa)
ENSFDAP00000002920annotation not available (87 aa)
TGFB2Transforming growth factor beta 2. (398 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (560 aa)
RBL1RB transcriptional corepressor like 1. (1042 aa)
SNW1SNW domain containing 1. (537 aa)
F11RJunctional adhesion molecule A. (299 aa)
STUB1STIP1 homology and U box-containing protein 1. (250 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ENSFDAP00000005475annotation not available (139 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
JUNBTranscription factor jun-B. (257 aa)
FSTFollistatin. (344 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
PPM1AProtein phosphatase 1A; Belongs to the PP2C family. (382 aa)
FBN1Fibrillin-1. (2819 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (768 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (758 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (570 aa)
DRAP1Dr1-associated corepressor. (191 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
PARD6APartitioning defective 6 like protein alpha. (347 aa)
H920_16943Zinc finger CCHC domain-containing protein 4. (249 aa)
CCNCCyclin-C; Belongs to the cyclin family. (283 aa)
CCNKCyclin K. (391 aa)
SKISki oncogene. (704 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CHRDL1Chordin-like protein 1. (452 aa)
SMURF2E3 ubiquitin-protein ligase. (742 aa)
CER1Cerberus. (267 aa)
ENSFDAP00000007247annotation not available (119 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
PARD3Partitioning defective 3 like protein. (1270 aa)
FSTL1Follistatin-related protein 1. (287 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
CDK9Cyclin dependent kinase 9. (378 aa)
STRAPSerine-threonine kinase receptor-associated protein. (350 aa)
ENSFDAP00000012053annotation not available (81 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (348 aa)
H920_10388NEDD8. (81 aa)
Arhgef18Rho guanine nucleotide exchange factor 18. (788 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
LOC104870588NEDD8. (78 aa)
SMAD7Mothers against decapentaplegic homolog. (229 aa)
Ube2mUbiquitin conjugating enzyme E2 M. (147 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (973 aa)
INHBBInhibin beta B chain. (305 aa)
SP1Transcription factor Sp1. (784 aa)
Fkbp1aPeptidylprolyl isomerase. (108 aa)
IRX6Iroquois-class homeodomain protein IRX-6. (447 aa)
MEIS3Meis homeobox 3. (304 aa)
Smad9Mothers against decapentaplegic homolog. (430 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
CCNT1Cyclin-T1; Belongs to the cyclin family. (727 aa)
IRX4Iroquois-class homeodomain protein IRX-4. (425 aa)
NCOR2Nuclear receptor corepressor 2. (2399 aa)
CgnCingulin. (916 aa)
CBLE3 ubiquitin-protein ligase CBL. (851 aa)
ITGB5Integrin subunit beta 5. (794 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
MTMR4Myotubularin-related protein 4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1194 aa)
NEDD4LE3 ubiquitin-protein ligase. (983 aa)
E2F5E2F transcription factor 5. (299 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (470 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3. (1131 aa)
CCNT2Cyclin-T2; Belongs to the cyclin family. (733 aa)
FSTL3Follistatin-related protein 3. (226 aa)
LTBP2Latent-transforming growth factor beta-binding protein 2. (1665 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (468 aa)
Zfyve16Zinc finger FYVE domain-containing protein 16. (1505 aa)
GREM2Gremlin. (168 aa)
CHRDL2Chordin-like protein 2. (431 aa)
E2F4E2F transcription factor 4. (408 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (761 aa)
ENSFDAP00000016282annotation not available (156 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1. (1554 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (494 aa)
TRIM33E3 ubiquitin-protein ligase TRIM33. (951 aa)
ENSFDAP00000017336annotation not available (225 aa)
GDF2Bone morphogenetic protein 3B. (417 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (744 aa)
MKXHomeobox protein Mohawk. (344 aa)
UbcPolyubiquitin-B. (235 aa)
FOXH1Forkhead box protein H1. (367 aa)
CDK8Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
Tfdp2Transcription factor Dp-2. (446 aa)
MEN1Menin. (616 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1555 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1399 aa)
RNF111E3 ubiquitin-protein ligase Arkadia; Belongs to the cyclin family. (987 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
ITGA8Integrin alpha-8; Belongs to the integrin alpha chain family. (992 aa)
Tgif1Homeobox protein TGIF1. (79 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
TFDP1Transcription factor. (410 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
USP9XPutative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2554 aa)
TGFB1Transforming growth factor beta-1. (333 aa)
CCNQCyclin-related protein FAM58A. (211 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1025 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (807 aa)
NCOR1Nuclear receptor corepressor 1. (2434 aa)
AmhMuellerian-inhibiting factor. (389 aa)
SKILSki-like protein. (679 aa)
UBA52KxDL motif containing 1. (232 aa)
FURINFurin; Belongs to the peptidase S8 family. (796 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.