33 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UBA52	KxDL motif containing 1. (232 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10. (729 aa)
	APH1B	Gamma-secretase subunit APH-1B. (257 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1191 aa)
	LOC104853662	Nuclease-sensitive element-binding protein 1. (296 aa)
	DLL4	Delta like canonical Notch ligand 4. (851 aa)
	PSENEN	Gamma-secretase subunit PEN-2. (101 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	NEURL1B	E3 ubiquitin-protein ligase NEURL1B. (304 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1106 aa)
	Ybx1	Coiled-coil domain-containing protein 30. (268 aa)
	MAML2	Mastermind-like protein 2. (989 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	IKZF1	DNA-binding protein Ikaros. (512 aa)
	PBX1	Pre-B-cell leukemia transcription factor 1. (391 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
	PBX2	Pre-B-cell leukemia transcription factor 2. (423 aa)
	HEY1	Hairy/enhancer-of-split related with YRPW motif protein 1. (304 aa)
	NOTCH3	Notch receptor 3. (2095 aa)
	DLGAP5	Disks large-associated protein 5. (835 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (671 aa)
	NEURL1	Neuralized-like protein 1A. (355 aa)
	EGFR	Receptor protein-tyrosine kinase. (1168 aa)
	HEYL	Hairy/enhancer-of-split related with YRPW motif-like protein. (329 aa)
	HES1	Transcription factor HES-1. (278 aa)
	MIB1	E3 ubiquitin-protein ligase MIB1. (929 aa)
	EGF	Pro-epidermal growth factor. (1155 aa)
	NCSTN	Nicastrin. (709 aa)
	TACC3	Transforming acidic coiled-coil-containing protein 3. (768 aa)
	WWP2	E3 ubiquitin-protein ligase. (870 aa)
	APH1A	Gamma-secretase subunit APH-1A. (265 aa)
	PBX3	Pre-B-cell leukemia transcription factor 3. (367 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	APH1A	ENSFDAP00000007509	ENSFDAP00000019695	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit APH-1A.	0.501
ADAM10	DLL1	ENSFDAP00000007509	ENSFDAP00000005058	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.760
ADAM10	DLL4	ENSFDAP00000007509	ENSFDAP00000017077	Disintegrin and metalloproteinase domain-containing protein 10.	Delta like canonical Notch ligand 4.	0.660
ADAM10	EGF	ENSFDAP00000007509	ENSFDAP00000000426	Disintegrin and metalloproteinase domain-containing protein 10.	Pro-epidermal growth factor.	0.477
ADAM10	JAG1	ENSFDAP00000007509	ENSFDAP00000017517	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.626
ADAM10	JAG2	ENSFDAP00000007509	ENSFDAP00000015702	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.632
ADAM10	NCSTN	ENSFDAP00000007509	ENSFDAP00000000329	Disintegrin and metalloproteinase domain-containing protein 10.	Nicastrin.	0.675
ADAM10	NOTCH3	ENSFDAP00000007509	ENSFDAP00000005542	Disintegrin and metalloproteinase domain-containing protein 10.	Notch receptor 3.	0.610
ADAM10	PSEN1	ENSFDAP00000007509	ENSFDAP00000016611	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.720
ADAM10	PSEN2	ENSFDAP00000007509	ENSFDAP00000009904	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.709
ADAM10	PSENEN	ENSFDAP00000007509	ENSFDAP00000016929	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit PEN-2.	0.633
APH1A	ADAM10	ENSFDAP00000019695	ENSFDAP00000007509	Gamma-secretase subunit APH-1A.	Disintegrin and metalloproteinase domain-containing protein 10.	0.501
APH1A	APH1B	ENSFDAP00000019695	ENSFDAP00000018358	Gamma-secretase subunit APH-1A.	Gamma-secretase subunit APH-1B.	0.957
APH1A	DLL1	ENSFDAP00000019695	ENSFDAP00000005058	Gamma-secretase subunit APH-1A.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.471
APH1A	DLL4	ENSFDAP00000019695	ENSFDAP00000017077	Gamma-secretase subunit APH-1A.	Delta like canonical Notch ligand 4.	0.465
APH1A	JAG1	ENSFDAP00000019695	ENSFDAP00000017517	Gamma-secretase subunit APH-1A.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.489
APH1A	JAG2	ENSFDAP00000019695	ENSFDAP00000015702	Gamma-secretase subunit APH-1A.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.471
APH1A	NCSTN	ENSFDAP00000019695	ENSFDAP00000000329	Gamma-secretase subunit APH-1A.	Nicastrin.	0.999
APH1A	NOTCH3	ENSFDAP00000019695	ENSFDAP00000005542	Gamma-secretase subunit APH-1A.	Notch receptor 3.	0.875
APH1A	PSEN1	ENSFDAP00000019695	ENSFDAP00000016611	Gamma-secretase subunit APH-1A.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.998