19 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pik3r2	Phosphoinositide-3-kinase regulatory subunit 2. (71 aa)
	CRK	CRK proto-oncogene, adaptor protein. (247 aa)
	Ubc	Polyubiquitin-B. (235 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1. (1211 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	UBA52	KxDL motif containing 1. (232 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
	ENSFDAP00000002920	annotation not available (87 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (851 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	VAV1	Proto-oncogene vav. (714 aa)
	Pik3r3	Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	SYK	Tyrosine-protein kinase. (629 aa)
	CRKL	Crk-like protein. (303 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	CRK	ENSFDAP00000003307	ENSFDAP00000019051	E3 ubiquitin-protein ligase CBL.	CRK proto-oncogene, adaptor protein.	0.995
CBL	CRKL	ENSFDAP00000003307	ENSFDAP00000014876	E3 ubiquitin-protein ligase CBL.	Crk-like protein.	0.996
CBL	ENSFDAP00000002920	ENSFDAP00000003307	ENSFDAP00000002920	E3 ubiquitin-protein ligase CBL.	annotation not available	0.900
CBL	FYN	ENSFDAP00000003307	ENSFDAP00000011404	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.985
CBL	GRB2	ENSFDAP00000003307	ENSFDAP00000004772	E3 ubiquitin-protein ligase CBL.	Growth factor receptor-bound protein 2.	0.995
CBL	LYN	ENSFDAP00000003307	ENSFDAP00000021246	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.974
CBL	PIK3CA	ENSFDAP00000003307	ENSFDAP00000020092	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.889
CBL	PIK3CB	ENSFDAP00000003307	ENSFDAP00000001430	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family.	0.938
CBL	PIK3CD	ENSFDAP00000003307	ENSFDAP00000012960	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.876
CBL	PIK3R1	ENSFDAP00000003307	ENSFDAP00000020905	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit alpha.	0.994
CBL	Pik3r2	ENSFDAP00000003307	ENSFDAP00000019939	E3 ubiquitin-protein ligase CBL.	Phosphoinositide-3-kinase regulatory subunit 2.	0.959
CBL	Pik3r3	ENSFDAP00000003307	ENSFDAP00000008318	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit gamma.	0.923
CBL	RAPGEF1	ENSFDAP00000003307	ENSFDAP00000018138	E3 ubiquitin-protein ligase CBL.	Rap guanine nucleotide exchange factor 1.	0.956
CBL	RPS27A	ENSFDAP00000003307	ENSFDAP00000014104	E3 ubiquitin-protein ligase CBL.	Ubiquitin-40S ribosomal protein S27a.	0.964
CBL	SYK	ENSFDAP00000003307	ENSFDAP00000012634	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.990
CBL	UBA52	ENSFDAP00000003307	ENSFDAP00000022032	E3 ubiquitin-protein ligase CBL.	KxDL motif containing 1.	0.957
CBL	Ubc	ENSFDAP00000003307	ENSFDAP00000018389	E3 ubiquitin-protein ligase CBL.	Polyubiquitin-B.	0.970
CBL	VAV1	ENSFDAP00000003307	ENSFDAP00000006587	E3 ubiquitin-protein ligase CBL.	Proto-oncogene vav.	0.976
CRK	CBL	ENSFDAP00000019051	ENSFDAP00000003307	CRK proto-oncogene, adaptor protein.	E3 ubiquitin-protein ligase CBL.	0.995
CRK	CRKL	ENSFDAP00000019051	ENSFDAP00000014876	CRK proto-oncogene, adaptor protein.	Crk-like protein.	0.939