STRINGSTRING
IRF8 IRF8 EIF4E2 EIF4E2 ENSFDAP00000015120 ENSFDAP00000015120 H920_05677 H920_05677 OAS1 OAS1 ATL1 ATL1 IFNAR1 IFNAR1 SOCS3 SOCS3 MID2 MID2 EIF4G2 EIF4G2 GBP6 GBP6 EIF4A3 EIF4A3 TRIM8 TRIM8 KPNB1 KPNB1 PTPN6 PTPN6 UBA7 UBA7 LOC104855004 LOC104855004 IFNB1 IFNB1 IFIT2 IFIT2 ABCE1 ABCE1 TRIM38 TRIM38 TRIM10 TRIM10 ENSFDAP00000010225 ENSFDAP00000010225 Ppm1b Ppm1b H920_07462 H920_07462 H920_00961 H920_00961 KPNA5 KPNA5 TRIM25 TRIM25 IRF4 IRF4 IRF9 IRF9 TRIM3 TRIM3 RNASEL RNASEL CAMK2B CAMK2B TRIM14 TRIM14 EIF4A2 EIF4A2 IFIT3 IFIT3 MID1 MID1 TRIM17 TRIM17 HERC5 HERC5 PRKCD PRKCD LOC104870764 LOC104870764 TRIM47 TRIM47 FOXS1 FOXS1 ENSFDAP00000006648 ENSFDAP00000006648 IRF5 IRF5 Camk2d Camk2d Eif4e Eif4e KPNA7 KPNA7 OASL OASL KPNA1 KPNA1 H920_03191 H920_03191 TYK2 TYK2 Gbp7 Gbp7 IRF2 IRF2 H920_06528 H920_06528 SOCS1 SOCS1 PTPN1 PTPN1 UBE2L6 UBE2L6 TRIM42 TRIM42 LOC104848183 LOC104848183 CIITA CIITA IFIT5 IFIT5 LOC104854401 LOC104854401 ENSFDAP00000001459 ENSFDAP00000001459 STAT1 STAT1 IFNG IFNG IRF6 IRF6 PTPN11 PTPN11 TRIM62 TRIM62 CAMK2A CAMK2A Usp18 Usp18 ARIH1 ARIH1 TRIM65 TRIM65 PDE12 PDE12 SUMO1 SUMO1 STAT2 STAT2 LOC104848838 LOC104848838 ATL2 ATL2 IFNGR2 IFNGR2 KPNA4 KPNA4 ISG20 ISG20 RSAD2 RSAD2 ENSFDAP00000021422 ENSFDAP00000021422 TRIM29 TRIM29 TRIM46 TRIM46 CAMK2G CAMK2G PLCG1 PLCG1 TRIM2 TRIM2 Eif4a1 Eif4a1 EIF4E1B EIF4E1B EIF4G3 EIF4G3 NEDD4 NEDD4 IRF1 IRF1 EIF4G1 EIF4G1 IRF3 IRF3 Eif2ak2 Eif2ak2 EIF4E3 EIF4E3 UBE2E1 UBE2E1 LOC104869977 LOC104869977 H920_00962 H920_00962 ENSFDAP00000017753 ENSFDAP00000017753 ENSFDAP00000017776 ENSFDAP00000017776 FLNB FLNB JAK2 JAK2 PIAS1 PIAS1 JAK1 JAK1 TRIM45 TRIM45 ENSFDAP00000018582 ENSFDAP00000018582 PTPN2 PTPN2 ATL3 ATL3 KPNA3 KPNA3 TRIM35 TRIM35 EGR1 EGR1 TRIM26 TRIM26
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IRF8Interferon regulatory factor 8. (426 aa)
EIF4E2Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
ENSFDAP00000015120annotation not available (546 aa)
H920_05677Calcium/calmodulin-dependent protein kinase type II subunit beta. (144 aa)
OAS12'-5'-oligoadenylate synthase 3. (357 aa)
ATL1Atlastin-1. (558 aa)
IFNAR1Interferon alpha/beta receptor 1. (492 aa)
SOCS3Suppressor of cytokine signaling 3. (227 aa)
MID2Putative E3 ubiquitin-protein ligase MID2. (732 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (907 aa)
GBP6Guanylate-binding protein 5. (588 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (425 aa)
TRIM8Putative E3 ubiquitin-protein ligase TRIM8. (551 aa)
KPNB1Importin subunit beta-1. (848 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
UBA7Ubiquitin-like modifier-activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1001 aa)
LOC104855004Interferon alpha-4. (187 aa)
IFNB1Interferon beta. (187 aa)
IFIT2Interferon-induced protein with tetratricopeptide repeats 2. (447 aa)
ABCE1ATP-binding cassette sub-family E member 1. (599 aa)
TRIM38Tripartite motif-containing protein 38. (467 aa)
TRIM10Tripartite motif containing 10. (341 aa)
ENSFDAP00000010225annotation not available (90 aa)
Ppm1bProtein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
H920_00961Tripartite motif-containing protein 6. (147 aa)
KPNA5Karyopherin subunit alpha 5. (500 aa)
TRIM25E3 ubiquitin/ISG15 ligase TRIM25. (561 aa)
IRF4Interferon regulatory factor 4. (379 aa)
IRF9Interferon regulatory factor 9. (402 aa)
TRIM3Tripartite motif-containing protein 3. (744 aa)
RNASEL2-5A-dependent ribonuclease. (628 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (359 aa)
TRIM14Tripartite motif containing 14. (325 aa)
EIF4A2Eukaryotic initiation factor 4A-II; Belongs to the DEAD box helicase family. (407 aa)
IFIT3Interferon-induced protein with tetratricopeptide repeats 3. (403 aa)
MID1Midline-1. (667 aa)
TRIM17E3 ubiquitin-protein ligase TRIM17. (478 aa)
HERC5Putative E3 ubiquitin-protein ligase HERC6. (925 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
LOC104870764Interferon-induced GTP-binding protein Mx2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (654 aa)
TRIM47Tripartite motif-containing protein 47. (448 aa)
FOXS1Forkhead box protein S1. (331 aa)
ENSFDAP00000006648annotation not available (129 aa)
IRF5Interferon regulatory factor 5. (497 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (512 aa)
Eif4eEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
KPNA7Importin subunit alpha; Functions in nuclear protein import. (495 aa)
OASL59 kDa 2'-5'-oligoadenylate synthase-like protein. (515 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
H920_03191Protein phosphatase 1B. (367 aa)
TYK2Tyrosine-protein kinase. (981 aa)
Gbp7Interferon-induced guanylate-binding protein 1. (627 aa)
IRF2Interferon regulatory factor. (349 aa)
H920_06528Interferon kappa. (242 aa)
SOCS1Suppressor of cytokine signaling 1. (193 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (436 aa)
UBE2L6Ubiquitin/ISG15-conjugating enzyme E2 L6. (153 aa)
TRIM42Tripartite motif-containing protein 42. (724 aa)
LOC10484818354 kDa 2'-5'-oligoadenylate synthase-like protein 2. (431 aa)
CIITAMHC class II transactivator. (1083 aa)
IFIT5Interferon-induced protein with tetratricopeptide repeats 5. (482 aa)
LOC104854401Probable ATP-dependent RNA helicase DDX58. (520 aa)
ENSFDAP00000001459annotation not available (194 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
IRF6Interferon regulatory factor 6. (462 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (600 aa)
TRIM62Tripartite motif containing 62. (352 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (489 aa)
Usp18Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (60 aa)
ARIH1RBR-type E3 ubiquitin transferase. (454 aa)
TRIM65Tripartite motif-containing protein 65. (403 aa)
PDE122',5'-phosphodiesterase 12. (609 aa)
SUMO1Small ubiquitin-related modifier. (110 aa)
STAT2Signal transducer and activator of transcription. (834 aa)
LOC104848838Interferon-induced protein with tetratricopeptide repeats 1B. (477 aa)
ATL2Atlastin-2. (561 aa)
IFNGR2Interferon gamma receptor 2. (319 aa)
KPNA4Importin subunit alpha; Functions in nuclear protein import. (498 aa)
ISG20Interferon-stimulated gene 20 kDa protein. (181 aa)
RSAD2Radical S-adenosyl methionine domain-containing protein 2. (351 aa)
ENSFDAP00000021422annotation not available (193 aa)
TRIM29Tripartite motif-containing protein 29. (584 aa)
TRIM46Tripartite motif-containing protein 46. (751 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (514 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
TRIM2Tripartite motif-containing protein 2. (764 aa)
Eif4a1Eukaryotic initiation factor 4A-I. (415 aa)
EIF4E1BEukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. (247 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1684 aa)
NEDD4E3 ubiquitin-protein ligase. (837 aa)
IRF1Interferon regulatory factor. (326 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1600 aa)
IRF3Interferon regulatory factor 3. (428 aa)
Eif2ak2Interferon-induced, double-stranded RNA-activated protein kinase. (448 aa)
EIF4E3Eukaryotic translation initiation factor 4E type 3; Belongs to the eukaryotic initiation factor 4E family. (181 aa)
UBE2E1Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
LOC104869977Tripartite motif-containing protein 34. (486 aa)
H920_00962Tripartite motif-containing protein 5. (476 aa)
ENSFDAP00000017753annotation not available (63 aa)
ENSFDAP00000017776annotation not available (72 aa)
FLNBFilamin-B. (2602 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
PIAS1E3 SUMO-protein ligase PIAS1. (647 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
TRIM45Tripartite motif-containing protein 45. (580 aa)
ENSFDAP00000018582annotation not available (321 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (389 aa)
ATL3Atlastin-3. (541 aa)
KPNA3Importin subunit alpha; Functions in nuclear protein import. (503 aa)
TRIM35Tripartite motif-containing protein 35. (445 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa)
TRIM26Tripartite motif-containing protein 26. (539 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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