STRINGSTRING
RPS27A RPS27A UBA52 UBA52 NBR1 NBR1 Ubc Ubc Map1lc3b Map1lc3b SQSTM1 SQSTM1 PEX5L PEX5L USP30 USP30 ILRUN ILRUN ATM ATM Gsap Gsap H920_13791 H920_13791 PEX5 PEX5 ENSFDAP00000002920 ENSFDAP00000002920
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
UBA52KxDL motif containing 1. (232 aa)
NBR1Next to BRCA1 gene 1 protein. (986 aa)
UbcPolyubiquitin-B. (235 aa)
Map1lc3bMicrotubule associated protein 1 light chain 3 beta. (112 aa)
SQSTM1Sequestosome-1. (400 aa)
PEX5LPEX5-related protein. (596 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (382 aa)
ILRUNN_BRCA1_IG domain-containing protein. (238 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3061 aa)
GsapGamma-secretase-activating protein. (175 aa)
H920_13791Uncharacterized protein. (176 aa)
PEX5Peroxisomal targeting signal 1 receptor. (640 aa)
ENSFDAP00000002920annotation not available (87 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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