(137 nodes) Oocyte meiosis network (Fukomys damarensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBXW11	F-box/WD repeat-containing protein 11. (539 aa)
	CPEB4	Cytoplasmic polyadenylation element-binding protein 4. (729 aa)
	YWHAG	14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
	Ppp2r1a	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (573 aa)
	YWHAB	14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa)
	ENSFDAP00000015944	annotation not available (350 aa)
	CAMK2A	Calcium/calmodulin-dependent protein kinase type II subunit alpha. (489 aa)
	ENSFDAP00000000144	annotation not available (263 aa)
	IGF1	Insulin-like growth factor I. (158 aa)
	CCNE2	G1/S-specific cyclin-E2; Belongs to the cyclin family. (405 aa)
	BTRC	F-box/WD repeat-containing protein 1A. (589 aa)
	MAPK12	Mitogen-activated protein kinase 12. (316 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (108 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (396 aa)
	YWHAQ	14-3-3 protein theta; Belongs to the 14-3-3 family. (304 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	ADCY9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
	ESPL1	Separin. (2108 aa)
	SKP1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (188 aa)
	FBXO5	F-box only protein 5. (450 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (317 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
	CALML4	Calmodulin like 4. (153 aa)
	MTRF1L	Mitochondrial translational release factor 1 like. (380 aa)
	CAMK2G	Calcium/calmodulin-dependent protein kinase type II subunit gamma. (514 aa)
	PLK1	Serine/threonine-protein kinase PLK. (604 aa)
	CALM3	Calmodulin 3. (148 aa)
	Mad2l1	Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
	CCNB2	Cyclin B2. (397 aa)
	RPS6KA3	Non-specific serine/threonine protein kinase. (727 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
	MAPK1	Mitogen-activated protein kinase. (320 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (776 aa)
	PLCZ1	Phosphoinositide phospholipase C. (643 aa)
	FBXO43	F-box only protein 43. (676 aa)
	MAPK3	Mitogen-activated protein kinase. (322 aa)
	Ywhaz	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
	CDK3	Cyclin dependent kinase 3. (297 aa)
	CDC20	Cell division cycle protein 20 like protein. (509 aa)
	REC8	Meiotic recombination protein REC8 like protein. (569 aa)
	PPP2R1B	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (653 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
	PGR	Progesterone receptor. (623 aa)
	H920_01229	Cullin-1; Belongs to the cullin family. (265 aa)
	H920_12625	Mitotic spindle assembly checkpoint protein MAD2A. (192 aa)
	H920_15675	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (135 aa)
	PPP3R1	Calcineurin subunit B type 1. (164 aa)
	MAPK13	Mitogen-activated protein kinase 13. (323 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1210 aa)
	MOS	Serine/threonine-protein kinase-transforming protein mos; Belongs to the protein kinase superfamily. (335 aa)
	ADCY4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1062 aa)
	PPP2R5A	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (425 aa)
	CDK2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
	ENSFDAP00000003237	annotation not available (159 aa)
	AURKA	Aurora kinase A. (401 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	ANAPC2	Anaphase-promoting complex subunit 2; Belongs to the cullin family. (827 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha. (343 aa)
	SPDYA	Speedy protein A. (310 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	PKMYT1	Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase. (490 aa)
	CDC16	Cell division cycle protein 16 like protein. (626 aa)
	Anapc13	Anaphase-promoting complex subunit 13. (74 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
	MAPK14	Mitogen-activated protein kinase. (321 aa)
	Calm1	Calmodulin; Belongs to the calmodulin family. (149 aa)
	ENSFDAP00000005382	annotation not available (406 aa)
	ANAPC5	Anaphase-promoting complex subunit 5. (755 aa)
	ADCY5	Adenylate cyclase type 5. (1182 aa)
	BUB1	Mitotic checkpoint serine/threonine-protein kinase BUB1. (1075 aa)
	ENSFDAP00000005725	annotation not available (477 aa)
	IGF1R	Insulin like growth factor 1 receptor. (1107 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (388 aa)
	Camk2d	Calcium/calmodulin-dependent protein kinase type II subunit delta. (512 aa)
	SLK	STE20-like serine/threonine-protein kinase. (1240 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (499 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (312 aa)
	Cpeb2	Cytoplasmic polyadenylation element-binding protein 2. (468 aa)
	CDC26	Transmembrane protein 71. (84 aa)
	CCNE1	G1/S-specific cyclin-E1; Belongs to the cyclin family. (405 aa)
	H920_16529	G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (277 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (733 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (964 aa)
	CAMK2B	Calcium/calmodulin dependent protein kinase II beta. (359 aa)
	ANAPC1	Anaphase-promoting complex subunit 1. (1944 aa)
	Pttg1	Securin. (199 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (704 aa)
	MAD1L1	Mitotic spindle assembly checkpoint protein MAD1. (717 aa)
	SMC3	Structural maintenance of chromosomes protein 3. (1162 aa)
	CDC20B	Cell division cycle protein 20 like protein B. (500 aa)
	ANAPC7	Anaphase-promoting complex subunit 7. (592 aa)
	ADCY1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (944 aa)
	Anapc11	Anaphase-promoting complex subunit 11. (84 aa)
	LOC104875317	Speedy protein B. (194 aa)
	CALM2	Calmodulin 2. (149 aa)
	MAPK11	Mitogen-activated protein kinase 11. (325 aa)
	YWHAE	14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
	Ppp2r5b	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2524 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (275 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (501 aa)
	H920_14855	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (262 aa)
	AURKB	Serine/threonine-protein kinase 12; Belongs to the protein kinase superfamily. (339 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (493 aa)
	CDC23	Cell division cycle protein 23 like protein. (597 aa)
	MAD2L2	Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
	ENSFDAP00000000887	annotation not available (132 aa)
	SMC1B	Structural maintenance of chromosomes 1B. (1237 aa)
	PTRHD1	Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
	CDK1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	SGO1	Shugoshin-like 1. (529 aa)
	ARSI	Arylsulfatase I. (575 aa)
	H920_20354	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	H920_06884	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
	YWHAH	14-3-3 protein eta; Belongs to the 14-3-3 family. (217 aa)
	LOC104855197	14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	H920_05677	Calcium/calmodulin-dependent protein kinase type II subunit beta. (144 aa)
	H920_02493	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
	Cpeb1	Cytoplasmic polyadenylation element-binding protein 1. (561 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
	RPS6KA6	Ribosomal protein S6 kinase A6. (857 aa)
	ANAPC10	Anaphase promoting complex subunit 10. (185 aa)
	AURKC	Zinc finger protein 548. (279 aa)
	H920_07431	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (136 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (585 aa)
	AR	Androgen receptor. (899 aa)
	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
	CDC27	Cell division cycle 27. (825 aa)
	STAG3	Cohesin subunit SA-3. (1214 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
	Ppp2ca	Serine/threonine-protein phosphatase. (275 aa)
	CCNB1	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (422 aa)
	EFCAB3	EF-hand calcium-binding domain-containing protein 3. (436 aa)
	TMEM82	Transmembrane protein 82. (299 aa)
	H920_11313	Anaphase-promoting complex subunit 13. (74 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSFDAP00000008869	ENSFDAP00000007671	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.581
ADCY1	ADCY4	ENSFDAP00000008869	ENSFDAP00000003091	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.576
ADCY1	ADCY5	ENSFDAP00000008869	ENSFDAP00000005552	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5.	0.572
ADCY1	ADCY6	ENSFDAP00000008869	ENSFDAP00000022712	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.571
ADCY1	ADCY7	ENSFDAP00000008869	ENSFDAP00000018532	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.608
ADCY1	ADCY8	ENSFDAP00000008869	ENSFDAP00000002763	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.824
ADCY1	ADCY9	ENSFDAP00000008869	ENSFDAP00000023003	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.810
ADCY1	CALM2	ENSFDAP00000008869	ENSFDAP00000009669	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 2.	0.688
ADCY1	CALM3	ENSFDAP00000008869	ENSFDAP00000020792	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 3.	0.688
ADCY1	CALML4	ENSFDAP00000008869	ENSFDAP00000021937	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.881
ADCY1	CAMK2A	ENSFDAP00000008869	ENSFDAP00000000106	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin-dependent protein kinase type II subunit alpha.	0.841
ADCY1	CAMK2B	ENSFDAP00000008869	ENSFDAP00000007825	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II beta.	0.781
ADCY1	CAMK2G	ENSFDAP00000008869	ENSFDAP00000021096	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin-dependent protein kinase type II subunit gamma.	0.828
ADCY1	Calm1	ENSFDAP00000008869	ENSFDAP00000005321	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin; Belongs to the calmodulin family.	0.688
ADCY1	Camk2d	ENSFDAP00000008869	ENSFDAP00000006172	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin-dependent protein kinase type II subunit delta.	0.840
ADCY1	EFCAB3	ENSFDAP00000008869	ENSFDAP00000016983	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	EF-hand calcium-binding domain-containing protein 3.	0.609
ADCY1	ENSFDAP00000000887	ENSFDAP00000008869	ENSFDAP00000000887	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	annotation not available	0.688
ADCY1	ENSFDAP00000003237	ENSFDAP00000008869	ENSFDAP00000003237	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	annotation not available	0.609
ADCY1	H920_05677	ENSFDAP00000008869	ENSFDAP00000014531	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin-dependent protein kinase type II subunit beta.	0.781
ADCY1	PRKACA	ENSFDAP00000008869	ENSFDAP00000003727	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha.	0.871