STRINGSTRING
PINK1 PINK1 NRAS NRAS STK35 STK35 ULK1 ULK1 NBR1 NBR1 RIT1 RIT1 RRAS RRAS RAB7A RAB7A Rras2 Rras2 RELA RELA GEM GEM REM1 REM1 TBC1D15 TBC1D15 RHOT1 RHOT1 ENSFDAP00000007466 ENSFDAP00000007466 USP8 USP8 MFN2 MFN2 TBC1D17 TBC1D17 RIT2 RIT2 RRAD RRAD Csnk2a1 Csnk2a1 SP1 SP1 NPAS1 NPAS1 USP31 USP31 ENSFDAP00000009406 ENSFDAP00000009406 JUN JUN MITF MITF EIF2AK3 EIF2AK3 ENSFDAP00000010317 ENSFDAP00000010317 Gsap Gsap Usp32 Usp32 MAPK9 MAPK9 RAB7B RAB7B H920_01844 H920_01844 TP53 TP53 Atg9a Atg9a FUNDC2 FUNDC2 MAPK10 MAPK10 CSNK2B CSNK2B TOMM7 TOMM7 USP43 USP43 Ly6g5b Ly6g5b CSDE1 CSDE1 Foxo3 Foxo3 Mfn1 Mfn1 FUNDC1 FUNDC1 ENSFDAP00000021852 ENSFDAP00000021852 UBA52 UBA52 HIF1A HIF1A GABARAPL2 GABARAPL2 CITED2 CITED2 FIS1 FIS1 NPAS3 NPAS3 METTL17 METTL17 REM2 REM2 BCL2L13 BCL2L13 ATF4 ATF4 H920_17227 H920_17227 USP15 USP15 Cfap70 Cfap70 AGFG2 AGFG2 AMBRA1 AMBRA1 ENSFDAP00000002789 ENSFDAP00000002789 OPTN OPTN E2F1 E2F1 ENSFDAP00000002920 ENSFDAP00000002920 Becn1 Becn1 MAPK8 MAPK8 GABARAP GABARAP TAX1BP1 TAX1BP1 BNIP3 BNIP3 CSNK2A2 CSNK2A2 HIF3A HIF3A HRAS HRAS MRAS MRAS LOC104861058 LOC104861058 TFE3 TFE3 TFEC TFEC KRAS KRAS Atg5 Atg5 USP30 USP30 RPS27A RPS27A ENSFDAP00000015009 ENSFDAP00000015009 RASL11B RASL11B ATG9B ATG9B BNIP3L BNIP3L PDIK1L PDIK1L BCL2L1 BCL2L1 PGAM5 PGAM5 USP19 USP19 SQSTM1 SQSTM1 LOC104849456 LOC104849456 GABARAPL1 GABARAPL1 ENSFDAP00000017826 ENSFDAP00000017826 TBK1 TBK1 SPEN SPEN USP11 USP11 Ubc Ubc H920_03798 H920_03798 AGFG1 AGFG1 TFEB TFEB USP4 USP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (446 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
STK35Serine/threonine kinase 35. (451 aa)
ULK1Serine/threonine-protein kinase ULK1. (1043 aa)
NBR1Next to BRCA1 gene 1 protein. (986 aa)
RIT1GTP-binding protein Rit1. (200 aa)
RRASRas-related protein R-Ras. (175 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
Rras2Ras-related protein R-Ras2. (168 aa)
RELATranscription factor p65. (545 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (274 aa)
TBC1D15TBC1 domain family member 15. (691 aa)
RHOT1Mitochondrial Rho GTPase 1. (698 aa)
ENSFDAP00000007466annotation not available (44 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1080 aa)
MFN2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (762 aa)
TBC1D17TBC1 domain family member 17. (587 aa)
RIT2GTP-binding protein Rit2. (217 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (311 aa)
Csnk2a1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
SP1Transcription factor Sp1. (784 aa)
NPAS1Neuronal PAS domain protein 1. (368 aa)
USP31Ubiquitin carboxyl-terminal hydrolase 31; Belongs to the peptidase C19 family. (1087 aa)
ENSFDAP00000009406annotation not available (150 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (254 aa)
MITFMicrophthalmia-associated transcription factor. (510 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3. (1007 aa)
ENSFDAP00000010317annotation not available (274 aa)
GsapGamma-secretase-activating protein. (175 aa)
Usp32Ubiquitin carboxyl-terminal hydrolase 32; Belongs to the peptidase C19 family. (1598 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
RAB7BRas-related protein Rab-7b. (199 aa)
H920_01844Polyubiquitin-B. (77 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
Atg9aAutophagy-related protein 9A. (839 aa)
FUNDC2FUN14 domain containing 2. (164 aa)
MAPK10Mitogen-activated protein kinase. (478 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (183 aa)
TOMM7Mitochondrial import receptor subunit TOM7 like protein. (55 aa)
USP43Ubiquitin carboxyl-terminal hydrolase 43; Belongs to the peptidase C19 family. (967 aa)
Ly6g5bUncharacterized protein. (193 aa)
CSDE1Cold shock domain-containing protein E1. (798 aa)
Foxo3Forkhead box protein O3. (674 aa)
Mfn1Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (239 aa)
FUNDC1FUN14 domain-containing protein 1. (211 aa)
ENSFDAP00000021852annotation not available (170 aa)
UBA52KxDL motif containing 1. (232 aa)
HIF1AHypoxia-inducible factor 1-alpha. (815 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
CITED2Cbp/p300-interacting transactivator 2. (220 aa)
FIS1Mitochondrial fission 1 protein. (152 aa)
NPAS3Neuronal PAS domain-containing protein 3. (743 aa)
METTL17Methyltransferase-like protein 17, mitochondrial. (468 aa)
REM2RRAD and GEM like GTPase 2. (339 aa)
BCL2L13Bcl-2-like protein 13. (465 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (352 aa)
H920_17227Beclin-1. (445 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
Cfap70Tetratricopeptide repeat protein 18. (593 aa)
AGFG2Arf-GAP domain and FG repeats-containing protein 2. (451 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1235 aa)
ENSFDAP00000002789annotation not available (79 aa)
OPTNOptineurin. (599 aa)
E2F1Transcription factor E2F1. (377 aa)
ENSFDAP00000002920annotation not available (87 aa)
Becn1Beclin-1. (448 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
TAX1BP1Tax1-binding protein 1 like protein. (839 aa)
BNIP3BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (194 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (315 aa)
HIF3AHypoxia-inducible factor 3-alpha. (667 aa)
HRASHRas proto-oncogene, GTPase. (191 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
LOC104861058Ubiquitin-like. (77 aa)
TFE3Transcription factor E3. (539 aa)
TFECTranscription factor EC. (435 aa)
KRASGTPase HRas. (189 aa)
Atg5Autophagy protein 5; Involved in autophagic vesicle formation. (198 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (382 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
ENSFDAP00000015009annotation not available (157 aa)
RASL11BRAS like family 11 member B. (220 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (852 aa)
BNIP3LBCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like. (185 aa)
PDIK1LSerine/threonine-protein kinase PDIK1L; Belongs to the protein kinase superfamily. (396 aa)
BCL2L1Bcl-2-like protein 1. (233 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (244 aa)
USP19Ubiquitin carboxyl-terminal hydrolase 19. (1357 aa)
SQSTM1Sequestosome-1. (400 aa)
LOC104849456E3 ubiquitin-protein ligase parkin. (243 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1. (113 aa)
ENSFDAP00000017826annotation not available (133 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
SPENSpen family transcriptional repressor. (3478 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (916 aa)
UbcPolyubiquitin-B. (235 aa)
H920_03798Mitochondrial Rho GTPase 2. (121 aa)
AGFG1Arf-GAP domain and FG repeats-containing protein 1. (506 aa)
TFEBTranscription factor EB. (318 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (964 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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