STRINGSTRING
MAP2K1 MAP2K1 PPP3CB PPP3CB GEM GEM NOS3 NOS3 REM1 REM1 JMJD7 JMJD7 Pik3r3 Pik3r3 RRAD RRAD ENSFDAP00000008900 ENSFDAP00000008900 Pla2g4b Pla2g4b NFATC2 NFATC2 PPP1R14B PPP1R14B Shc2 Shc2 MAPK11 MAPK11 AKT3 AKT3 PPP3CA PPP3CA PLA2G4E PLA2G4E HRAS HRAS LRRC45 LRRC45 MAPKAPK3 MAPKAPK3 PIK3CD PIK3CD KRAS KRAS CASP9 CASP9 MAPK12 MAPK12 NRAS NRAS AKT2 AKT2 HSPB1 HSPB1 SPHK2 SPHK2 CSDE1 CSDE1 PIK3R1 PIK3R1 PLCG1 PLCG1 MAPK1 MAPK1 PIK3CA PIK3CA Pik3r2 Pik3r2 KDR KDR MAPK3 MAPK3 PRKCA PRKCA PPP3R1 PPP3R1 PTK2 PTK2 RAC2 RAC2 ENSFDAP00000016516 ENSFDAP00000016516 Cdc42 Cdc42 SPHK1 SPHK1 PRKCG PRKCG PLA2G4A PLA2G4A PRKCB PRKCB BAD BAD MAPK14 MAPK14 LPXN LPXN RAC1 RAC1 AKT1 AKT1 PTGS2 PTGS2 PXN PXN Map2k2 Map2k2 RAF1 RAF1 MAPK13 MAPK13 Sh2d7 Sh2d7 MAPKAPK2 MAPKAPK2 PPP3CC PPP3CC PIK3CB PIK3CB RAC3 RAC3 PLA2G4C PLA2G4C LOC104852000 LOC104852000 Vegfa Vegfa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (388 aa)
PPP3CBSerine/threonine-protein phosphatase. (499 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1206 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (274 aa)
JMJD7JmjC domain-containing protein 7. (306 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (311 aa)
ENSFDAP00000008900annotation not available (172 aa)
Pla2g4bPhospholipase A2. (769 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2. (850 aa)
PPP1R14BProtein phosphatase 1 regulatory subunit 14B. (122 aa)
Shc2SHC-transforming protein 2. (421 aa)
MAPK11Mitogen-activated protein kinase 11. (325 aa)
AKT3Non-specific serine/threonine protein kinase. (480 aa)
PPP3CASerine/threonine-protein phosphatase. (501 aa)
PLA2G4EPhospholipase A2. (589 aa)
HRASHRas proto-oncogene, GTPase. (191 aa)
LRRC45Leucine-rich repeat-containing protein 45. (662 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
KRASGTPase HRas. (189 aa)
CASP9Caspase-9; Belongs to the peptidase C14A family. (406 aa)
MAPK12Mitogen-activated protein kinase 12. (316 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
AKT2RAC-beta serine/threonine-protein kinase. (481 aa)
HSPB1Heat shock protein beta-1; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (186 aa)
SPHK2Sphingosine kinase 2. (653 aa)
CSDE1Cold shock domain-containing protein E1. (798 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Pik3r2Phosphoinositide-3-kinase regulatory subunit 2. (71 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1346 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
PRKCAProtein kinase C alpha type. (672 aa)
PPP3R1Calcineurin subunit B type 1. (164 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1083 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
ENSFDAP00000016516annotation not available (156 aa)
Cdc42Cell division control protein 42 like protein. (191 aa)
SPHK1Sphingosine kinase 1. (406 aa)
PRKCGProtein kinase C. (680 aa)
PLA2G4APhospholipase A2. (749 aa)
PRKCBProtein kinase C beta type. (586 aa)
BADBcl2 antagonist of cell death. (162 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
LPXNLeupaxin. (380 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (199 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (601 aa)
PXNPaxillin. (585 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (370 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
MAPK13Mitogen-activated protein kinase 13. (323 aa)
Sh2d7SH2 domain-containing protein 7. (274 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (399 aa)
PPP3CCSerine/threonine-protein phosphatase. (493 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (190 aa)
PLA2G4CCytosolic phospholipase A2 gamma. (610 aa)
LOC1048520001-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1255 aa)
VegfaVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (186 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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