STRINGSTRING
H920_12116 H920_12116 Ctnnb1 Ctnnb1 AMOT AMOT PPP2R1B PPP2R1B NKD1 NKD1 FZD3 FZD3 WNT10A WNT10A CTNNA2 CTNNA2 FGF1 FGF1 WNT7A WNT7A Ppp2ca Ppp2ca WNT5A WNT5A FZD6 FZD6 PPP2R2C PPP2R2C WNT1 WNT1 TP73 TP73 SMAD7 SMAD7 GDF5 GDF5 Stk3 Stk3 H920_10553 H920_10553 LRRC1 LRRC1 MOB1A MOB1A AREG AREG YWHAE YWHAE LATS1 LATS1 ENSFDAP00000011016 ENSFDAP00000011016 WNT11 WNT11 PPP2CB PPP2CB WNT2B WNT2B WNT10B WNT10B CTNNA3 CTNNA3 WNT3A WNT3A DLG5 DLG5 FZD7 FZD7 FZD8 FZD8 GSK3B GSK3B LEF1 LEF1 H920_14855 H920_14855 LLGL1 LLGL1 H920_00677 H920_00677 WNT8A WNT8A LOC104866712 LOC104866712 ENSFDAP00000012675 ENSFDAP00000012675 Actb Actb YAP1 YAP1 SCRIB SCRIB AXIN2 AXIN2 H920_09656 H920_09656 H920_12193 H920_12193 TGFBR1 TGFBR1 Limd1 Limd1 PATJ PATJ LDAH LDAH TGFB3 TGFB3 FZD4 FZD4 PARD6A PARD6A RASSF6 RASSF6 PPP2R2B PPP2R2B TCF7L1 TCF7L1 H920_02493 H920_02493 LOC104855197 LOC104855197 YWHAH YWHAH ACTRT2 ACTRT2 DVL1 DVL1 ACTRT1 ACTRT1 LOC104856231 LOC104856231 H920_06884 H920_06884 SMAD2 SMAD2 NF2 NF2 Ccnd3 Ccnd3 CDH1 CDH1 TP53BP2 TP53BP2 Sry Sry PPP2R2D PPP2R2D SERPINE1 SERPINE1 AXIN1 AXIN1 DLG1 DLG1 Amh Amh DLG3 DLG3 BMPR2 BMPR2 TGFB1 TGFB1 CRB2 CRB2 WNT3 WNT3 WNT9A WNT9A LATS2 LATS2 CSNK1D CSNK1D APC APC TGFBR2 TGFBR2 TGFB2 TGFB2 GLI2 GLI2 WWC1 WWC1 Ccnd2 Ccnd2 APC2 APC2 FZD9 FZD9 TEAD4 TEAD4 MPP5 MPP5 TEAD2 TEAD2 BMPR1B BMPR1B Myo15b Myo15b Ajuba Ajuba BIRC3 BIRC3 BMP7 BMP7 PARD6G PARD6G MOB1B MOB1B FRMD6 FRMD6 SMAD3 SMAD3 SMAD1 SMAD1 LLGL2 LLGL2 PRKCZ PRKCZ WNT5B WNT5B DVL3 DVL3 PPP1CB PPP1CB FZD1 FZD1 TEAD1 TEAD1 BIRC5 BIRC5 BMPR1A BMPR1A WNT9B WNT9B H920_02843 H920_02843 PARD3 PARD3 WNT6 WNT6 WWTR1 WWTR1 TCF7 TCF7 H920_05210 H920_05210 NKD2 NKD2 WNT4 WNT4 DVL2 DVL2 BMP6 BMP6 SNAI2 SNAI2 ID1 ID1 TCF7L2 TCF7L2 SMAD4 SMAD4 H920_18824 H920_18824 DLG4 DLG4 PRKCI PRKCI H920_06235 H920_06235 BMP4 BMP4 Ywhaz Ywhaz CRB1 CRB1 H920_16434 H920_16434 Wtip Wtip FZD10 FZD10 ENSFDAP00000000144 ENSFDAP00000000144 WNT7B WNT7B BTRC BTRC CCND1 CCND1 AFP AFP WNT16 WNT16 PPP2R2A PPP2R2A BMP2 BMP2 FBXW11 FBXW11 PARD6B PARD6B SOX2 SOX2 RASSF1 RASSF1 YWHAG YWHAG CTNNA1 CTNNA1 Ppp2r1a Ppp2r1a Itgb2 Itgb2 YWHAB YWHAB WNT2 WNT2 PPP1CA PPP1CA PPP1CC PPP1CC ACTG1 ACTG1 ACTL8 ACTL8 BMP5 BMP5 YWHAQ YWHAQ Csnk1e Csnk1e MYO15A MYO15A BIRC2 BIRC2 SAV1 SAV1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H920_12116Protein kinase C iota type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (381 aa)
Ctnnb1Catenin beta-1. (781 aa)
AMOTAngiomotin. (1069 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (653 aa)
NKD1Protein naked cuticle like protein 1. (465 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
WNT10AWnt family member 10A. (351 aa)
CTNNA2Catenin alpha-2. (954 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
Ppp2caSerine/threonine-protein phosphatase. (275 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (596 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (430 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (645 aa)
SMAD7Mothers against decapentaplegic homolog. (229 aa)
GDF5Growth differentiation factor 5. (495 aa)
Stk3Serine/threonine-protein kinase 3. (493 aa)
H920_10553Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (459 aa)
LRRC1Leucine-rich repeat-containing protein 1. (471 aa)
MOB1AMps one binder kinase activator-like 1B. (215 aa)
AREGAmphiregulin. (242 aa)
YWHAE14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
LATS1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (1130 aa)
ENSFDAP00000011016annotation not available (383 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (299 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
CTNNA3Catenin alpha-3. (895 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
DLG5Disks large like protein 5; Belongs to the MAGUK family. (1818 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (558 aa)
FZD8Frizzled class receptor 8. (409 aa)
GSK3BGlycogen synthase kinase 3 beta. (442 aa)
LEF1Lymphoid enhancer-binding factor 1. (329 aa)
H920_1485514-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (262 aa)
LLGL1Lethal(2) giant larvae protein like protein 1. (1033 aa)
H920_00677Protein kinase C iota type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (559 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
LOC104866712Disks large like protein 2. (467 aa)
ENSFDAP00000012675annotation not available (222 aa)
ActbActin, cytoplasmic 1. (375 aa)
YAP1Yorkie like protein. (397 aa)
SCRIBScribble planar cell polarity protein. (1614 aa)
AXIN2Axin-2. (860 aa)
H920_09656Catenin beta-1. (83 aa)
H920_12193Actin, cytoplasmic type 8; Belongs to the actin family. (187 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (470 aa)
Limd1LIM domains containing 1. (405 aa)
PATJInaD-like protein. (1668 aa)
LDAHUncharacterized protein. (347 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
PARD6APartitioning defective 6 like protein alpha. (347 aa)
RASSF6Ras association domain-containing protein 6. (356 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform. (509 aa)
TCF7L1Transcription factor 7-like 1. (453 aa)
H920_02493Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
LOC10485519714-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (217 aa)
ACTRT2Actin-related protein T2; Belongs to the actin family. (377 aa)
DVL1Segment polarity protein dishevelled like protein DVL-1. (696 aa)
ACTRT1Actin-related protein T1; Belongs to the actin family. (377 aa)
LOC104856231Actin; Belongs to the actin family. (945 aa)
H920_0688414-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
NF2Merlin. (596 aa)
Ccnd3G1/S-specific cyclin-D3; Belongs to the cyclin family. (96 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (895 aa)
TP53BP2Apoptosis-stimulating of p53 protein 2. (1100 aa)
SrySex-determining region Y protein. (215 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (431 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
AXIN1Axin-1. (865 aa)
DLG1Disks large like protein 1; Belongs to the MAGUK family. (927 aa)
AmhMuellerian-inhibiting factor. (389 aa)
DLG3Disks large like protein 3; Belongs to the MAGUK family. (850 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1025 aa)
TGFB1Transforming growth factor beta-1. (333 aa)
CRB2Crumbs like protein 2. (998 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
LATS2Non-specific serine/threonine protein kinase. (892 aa)
CSNK1DCasein kinase I isoform delta. (412 aa)
APCAdenomatous polyposis coli protein. (2857 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (560 aa)
TGFB2Transforming growth factor beta 2. (398 aa)
GLI2Zinc finger protein GLI2. (1569 aa)
WWC1Protein KIBRA. (1099 aa)
Ccnd2G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa)
APC2Adenomatous polyposis coli protein 2. (1982 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (399 aa)
TEAD4Transcriptional enhancer factor TEF-3. (427 aa)
MPP5MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (675 aa)
TEAD2Transcriptional enhancer factor TEF-4. (447 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
Myo15bMyosin XVB. (175 aa)
AjubaProtein ajuba. (121 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (644 aa)
BMP7Bone morphogenetic protein 7. (432 aa)
PARD6GPartitioning defective 6 like protein gamma. (383 aa)
MOB1BMps one binder kinase activator-like 1A. (212 aa)
FRMD6FERM domain-containing protein 6. (622 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
LLGL2Lethal(2) giant larvae protein like protein 2. (1020 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (409 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
DVL3Segment polarity protein dishevelled like protein DVL-3. (606 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (312 aa)
FZD1Frizzled class receptor 1. (486 aa)
TEAD1Transcriptional enhancer factor TEF-1. (436 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (117 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
H920_02843Putative myosin-XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (498 aa)
PARD3Partitioning defective 3 like protein. (1270 aa)
WNT6Wnt family member 6. (363 aa)
WWTR1WW domain-containing transcription regulator protein 1. (413 aa)
TCF7Transcription factor 7. (302 aa)
H920_05210Actin-41; Belongs to the actin family. (193 aa)
NKD2Protein naked cuticle like protein 2. (409 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (327 aa)
DVL2Segment polarity protein dishevelled like protein DVL-2. (736 aa)
BMP6Bone morphogenetic protein 6. (319 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
ID1DNA-binding protein inhibitor ID-1. (151 aa)
TCF7L2Transcription factor 7 like 2. (413 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
H920_18824Protein kinase C iota type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (659 aa)
DLG4Disks large like protein 4; Belongs to the MAGUK family. (767 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (560 aa)
H920_06235Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (326 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
Ywhaz14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
CRB1Crumbs like protein 1. (1271 aa)
H920_16434Serine/threonine-protein kinase 3. (439 aa)
WtipWilms tumor protein 1-interacting protein. (206 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (545 aa)
ENSFDAP00000000144annotation not available (263 aa)
WNT7BWnt family member 7B. (349 aa)
BTRCF-box/WD repeat-containing protein 1A. (589 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
AFPAlpha-fetoprotein. (609 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform. (458 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
FBXW11F-box/WD repeat-containing protein 11. (539 aa)
PARD6BPartitioning defective 6 like protein beta. (350 aa)
SOX2Transcription factor SOX-2. (264 aa)
RASSF1Ras association domain family member 1. (339 aa)
YWHAG14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
CTNNA1Catenin alpha-1. (906 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (573 aa)
Itgb2Integrin beta. (461 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (317 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
YWHAQ14-3-3 protein theta; Belongs to the 14-3-3 family. (304 aa)
Csnk1eCasein kinase I isoform epsilon; Belongs to the protein kinase superfamily. (416 aa)
MYO15AMyosin-XV; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3398 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (618 aa)
SAV1Protein salvador like protein 1. (384 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
Server load: low (26%) [HD]