STRINGSTRING
AKT2 AKT2 PIK3CA PIK3CA MAPK1 MAPK1 COL3A1 COL3A1 H920_18824 H920_18824 PIK3R1 PIK3R1 LYN LYN ACTL8 ACTL8 ACTG1 ACTG1 PPP1CC PPP1CC PPP1CA PPP1CA ITGB1 ITGB1 RHOA RHOA ITGA2 ITGA2 ADCY6 ADCY6 F2R F2R ADCY9 ADCY9 LOC104871245 LOC104871245 PIK3CB PIK3CB P2RX1 P2RX1 FGA FGA VWF VWF MAPK12 MAPK12 LOC104852000 LOC104852000 PLA2G4C PLA2G4C RAP1A RAP1A PRKACB PRKACB ORAI1 ORAI1 VAMP8 VAMP8 MAPK13 MAPK13 ADCY8 ADCY8 ROCK1 ROCK1 PRKG2 PRKG2 ADCY4 ADCY4 GNA13 GNA13 PTGS1 PTGS1 SRMS SRMS PRKACA PRKACA PIK3R5 PIK3R5 AKT1 AKT1 ADCY3 ADCY3 Rhoc Rhoc GNAI3 GNAI3 ITPR1 ITPR1 FCER1G FCER1G MAPK14 MAPK14 ADCY5 ADCY5 PRKCZ PRKCZ PLCB4 PLCB4 STIM1 STIM1 ENSFDAP00000006459 ENSFDAP00000006459 PPP1CB PPP1CB NOS3 NOS3 MYL12B MYL12B JMJD7 JMJD7 ADCY2 ADCY2 H920_05210 H920_05210 GNAI1 GNAI1 RASGRP2 RASGRP2 Pik3r3 Pik3r3 ADCY1 ADCY1 PLCB1 PLCB1 ENSFDAP00000009191 ENSFDAP00000009191 RASGRP1 RASGRP1 F2 F2 Pla2g4b Pla2g4b GUCY1B1 GUCY1B1 PIK3CG PIK3CG LOC104865357 LOC104865357 MYLK MYLK H920_10553 H920_10553 GNAQ GNAQ MAPK11 MAPK11 LRRC15 LRRC15 FERMT3 FERMT3 ITPR3 ITPR3 AKT3 AKT3 PLCB3 PLCB3 APBB1IP APBB1IP LOC104865308 LOC104865308 ROCK2 ROCK2 FYN FYN PLCB2 PLCB2 COL1A2 COL1A2 PLA2G4E PLA2G4E ENSFDAP00000012096 ENSFDAP00000012096 H920_00677 H920_00677 SYK SYK Actb Actb PIK3CD PIK3CD H920_12193 H920_12193 Dgcr6l Dgcr6l PTK6 PTK6 H920_12439 H920_12439 ARHGEF12 ARHGEF12 LOC104850622 LOC104850622 LCP2 LCP2 H920_08475 H920_08475 RDH14 RDH14 ACTRT2 ACTRT2 PPP1R12A PPP1R12A ACTRT1 ACTRT1 LOC104856231 LOC104856231 GUCY1A1 GUCY1A1 ARHGAP35 ARHGAP35 PLA2G4A PLA2G4A DHRSX DHRSX GUCY1A2 GUCY1A2 P2RY1 P2RY1 F2RL3 F2RL3 PTRHD1 PTRHD1 COL1A1 COL1A1 Itgb3 Itgb3 Rap1b Rap1b GNAI2 GNAI2 TLN2 TLN2 ARHGEF1 ARHGEF1 FGG FGG PIK3R6 PIK3R6 MYLK4 MYLK4 Snap23 Snap23 RDH13 RDH13 MYLK2 MYLK2 ITPR2 ITPR2 BTK BTK H920_19642 H920_19642 TLN1 TLN1 ADCY7 ADCY7 GP1BA GP1BA FGB FGB H920_12116 H920_12116 P2RY12 P2RY12 MAPK3 MAPK3 PRKG1 PRKG1 Pik3r2 Pik3r2 MYLK3 MYLK3 PRKCI PRKCI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT2RAC-beta serine/threonine-protein kinase. (481 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
COL3A1Collagen alpha-1(III) chain. (1463 aa)
H920_18824Protein kinase C iota type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (659 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
LYNTyrosine-protein kinase. (512 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (317 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (803 aa)
RHOATransforming protein RhoA. (193 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (403 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
LOC104871245Guanylate cyclase soluble subunit beta-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (615 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
FGAFibrinogen alpha chain. (847 aa)
VWFVon Willebrand factor. (2568 aa)
MAPK12Mitogen-activated protein kinase 12. (316 aa)
LOC1048520001-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1255 aa)
PLA2G4CCytosolic phospholipase A2 gamma. (610 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (396 aa)
ORAI1Calcium release-activated calcium channel protein 1. (187 aa)
VAMP8Vesicle-associated membrane protein 8. (101 aa)
MAPK13Mitogen-activated protein kinase 13. (323 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1210 aa)
ROCK1Rho-associated protein kinase 1; Belongs to the peptidase C19 family. (1368 aa)
PRKG2cGMP-dependent protein kinase 2. (762 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1062 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (373 aa)
PTGS1Prostaglandin G/H synthase 1. (600 aa)
SRMSSrc-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites. (468 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (343 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 6. (874 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
RhocRas homolog family member C. (193 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
ADCY5Adenylate cyclase type 5. (1182 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (409 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
STIM1Stromal interaction molecule 1. (801 aa)
ENSFDAP00000006459annotation not available (432 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (312 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1206 aa)
MYL12BMyosin regulatory light polypeptide 9. (172 aa)
JMJD7JmjC domain-containing protein 7. (306 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (964 aa)
H920_05210Actin-41; Belongs to the actin family. (193 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (314 aa)
RASGRP2RAS guanyl-releasing protein 2. (608 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (944 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
ENSFDAP00000009191annotation not available (131 aa)
RASGRP1RAS guanyl-releasing protein 1. (796 aa)
F2Coagulation factor II, thrombin. (565 aa)
Pla2g4bPhospholipase A2. (769 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (617 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1095 aa)
LOC104865357Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas. (347 aa)
MYLKMyosin light chain kinase, smooth muscle. (1926 aa)
H920_10553Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (459 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (313 aa)
MAPK11Mitogen-activated protein kinase 11. (325 aa)
LRRC15Leucine-rich repeat-containing protein 15. (476 aa)
FERMT3Fermitin family like protein 3. (614 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2524 aa)
AKT3Non-specific serine/threonine protein kinase. (480 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1197 aa)
APBB1IPAmyloid beta A4 protein-binding family B member 1-interacting protein. (508 aa)
LOC104865308Neuroendocrine secretory protein 55. (229 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2. (1348 aa)
FYNTyrosine-protein kinase. (537 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1158 aa)
COL1A2Collagen alpha-2(I) chain. (1366 aa)
PLA2G4EPhospholipase A2. (589 aa)
ENSFDAP00000012096annotation not available (135 aa)
H920_00677Protein kinase C iota type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (559 aa)
SYKTyrosine-protein kinase. (629 aa)
ActbActin, cytoplasmic 1. (375 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
H920_12193Actin, cytoplasmic type 8; Belongs to the actin family. (187 aa)
Dgcr6lProtein DGCR6. (161 aa)
PTK6Protein-tyrosine kinase 6. (451 aa)
H920_12439Prostacyclin receptor. (185 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1543 aa)
LOC104850622Guanine nucleotide-binding protein G(S) subunit alpha. (394 aa)
LCP2Lymphocyte cytosolic protein 2. (520 aa)
H920_08475Thromboxane-A synthase; Belongs to the cytochrome P450 family. (79 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (228 aa)
ACTRT2Actin-related protein T2; Belongs to the actin family. (377 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1005 aa)
ACTRT1Actin-related protein T1; Belongs to the actin family. (377 aa)
LOC104856231Actin; Belongs to the actin family. (945 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (599 aa)
ARHGAP35Rho GTPase activating protein 35. (1522 aa)
PLA2G4APhospholipase A2. (749 aa)
DHRSXDehydrogenase/reductase X-linked. (272 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (631 aa)
P2RY1p2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
F2RL3Proteinase-activated receptor 4; Belongs to the G-protein coupled receptor 1 family. (387 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
COL1A1Collagen alpha-1(I) chain. (1453 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (761 aa)
Rap1bRas-related protein Rap-1b. (184 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
TLN2Talin-2. (2542 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (943 aa)
FGGFibrinogen gamma chain. (445 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (738 aa)
MYLK4Myosin light chain kinase family member 4. (387 aa)
Snap23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
RDH13Retinol dehydrogenase 13. (312 aa)
MYLK2Myosin light chain kinase 2. (579 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
BTKTyrosine-protein kinase. (658 aa)
H920_19642Vasodilator-stimulated phosphoprotein. (108 aa)
TLN1Talin-1. (2541 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
GP1BAPlatelet glycoprotein Ib alpha chain. (672 aa)
FGBFibrinogen beta chain. (479 aa)
H920_12116Protein kinase C iota type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (381 aa)
P2RY12p2Y purinoceptor 12. (342 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
PRKG1cGMP-dependent protein kinase 1; Belongs to the protein kinase superfamily. (686 aa)
Pik3r2Phosphoinositide-3-kinase regulatory subunit 2. (71 aa)
MYLK3Putative myosin light chain kinase 3. (778 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (560 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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