STRINGSTRING
H920_17962 H920_17962 PTGS2 PTGS2 TAB1 TAB1 NCF1 NCF1 CYBA CYBA IFNG IFNG STAT1 STAT1 H920_12529 H920_12529 TAB2 TAB2 H920_13310 H920_13310 IL10 IL10 IRAK1 IRAK1 Itgb2 Itgb2 MAPK13 MAPK13 TGFB2 TGFB2 H920_12959 H920_12959 Irak4 Irak4 TLR2 TLR2 ENSFDAP00000003552 ENSFDAP00000003552 MAPK12 MAPK12 H920_17964 H920_17964 HLA-DOA HLA-DOA ITGB1 ITGB1 IFNGR2 IFNGR2 H920_07716 H920_07716 FOS FOS TGFB1 TGFB1 CYBB CYBB MAPK1 MAPK1 Fam229a Fam229a NFKBIB NFKBIB MAPK3 MAPK3 Il1b Il1b JAK1 JAK1 NOS2 NOS2 JAK2 JAK2 NFKB1 NFKB1 Eef1a1 Eef1a1 H920_04312 H920_04312 HLA-DRA HLA-DRA LOC104857295 LOC104857295 MARCKSL1 MARCKSL1 H920_17965 H920_17965 IL12B IL12B NFKBIA NFKBIA H920_10546 H920_10546 C3 C3 H920_17960 H920_17960 TRAF6 TRAF6 MAP3K7 MAP3K7 H920_01787 H920_01787 ENSFDAP00000014417 ENSFDAP00000014417 LOC104849006 LOC104849006 TGFB3 TGFB3 H920_04384 H920_04384 PTPN6 PTPN6 ENSFDAP00000012168 ENSFDAP00000012168 H920_13644 H920_13644 LOC104872531 LOC104872531 H920_07367 H920_07367 H920_03480 H920_03480 MAPK11 MAPK11 H920_04309 H920_04309 LOC104874234 LOC104874234 ELK1 ELK1 ENSFDAP00000009864 ENSFDAP00000009864 ITGA4 ITGA4 Fcgr1a Fcgr1a H920_04300 H920_04300 JUN JUN H920_05759 H920_05759 ENSFDAP00000009051 ENSFDAP00000009051 LOC104874226 LOC104874226 MYD88 MYD88 IL1A IL1A H920_13645 H920_13645 H920_04299 H920_04299 H920_04301 H920_04301 NOXA1 NOXA1 H920_05193 H920_05193 TLR4 TLR4 HLA-DOB HLA-DOB NCF4 NCF4 RELA RELA PRKCB PRKCB HLA-DMA HLA-DMA MAPK14 MAPK14 NCF2 NCF2 IL12A IL12A TNF TNF ENSFDAP00000004185 ENSFDAP00000004185 EEF1A2 EEF1A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H920_17962Ig heavy chain V region 1B43. (122 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (601 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
NCF1Neutrophil cytosol factor 1. (390 aa)
CYBACytochrome b-245 light chain. (170 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
H920_12529Elongation factor 1-alpha 1. (390 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
H920_13310Ig heavy chain V-III region VH26. (180 aa)
IL10Interleukin-10. (178 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (453 aa)
Itgb2Integrin beta. (461 aa)
MAPK13Mitogen-activated protein kinase 13. (323 aa)
TGFB2Transforming growth factor beta 2. (398 aa)
H920_12959Elongation factor 1-alpha 1. (352 aa)
Irak4Interleukin-1 receptor-associated kinase 4. (459 aa)
TLR2Toll-like receptor 2. (718 aa)
ENSFDAP00000003552annotation not available (449 aa)
MAPK12Mitogen-activated protein kinase 12. (316 aa)
H920_17964Ig heavy chain V region 1B43. (121 aa)
HLA-DOAHLA class II histocompatibility antigen, DO alpha chain; Belongs to the MHC class II family. (289 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (803 aa)
IFNGR2Interferon gamma receptor 2. (319 aa)
H920_07716DLA class II histocompatibility antigen, DR-1 beta chain. (137 aa)
FOSProto-oncogene c-Fos. (380 aa)
TGFB1Transforming growth factor beta-1. (333 aa)
CYBBCytochrome b-245 heavy chain. (570 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
Fam229aFamily with sequence similarity 229 member A. (95 aa)
NFKBIBNF-kappa-B inhibitor beta. (358 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1149 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (894 aa)
Eef1a1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
H920_04312Ig heavy chain V-III region VH26. (180 aa)
HLA-DRAMamu class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (254 aa)
LOC104857295Low affinity immunoglobulin gamma Fc region receptor III-B. (260 aa)
MARCKSL1MARCKS-related protein. (173 aa)
H920_17965Ig heavy chain V region 1B43. (122 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
NFKBIANF-kappa-B inhibitor alpha. (224 aa)
H920_10546Ig heavy chain V-III region VH26. (184 aa)
C3Complement C3. (1489 aa)
H920_17960Ig heavy chain V region 1B43. (137 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (606 aa)
H920_01787Ig heavy chain V region 441. (173 aa)
ENSFDAP00000014417annotation not available (184 aa)
LOC104849006HLA class II histocompatibility antigen, DM beta chain. (263 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
H920_04384Elongation factor 1-alpha 1. (383 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ENSFDAP00000012168annotation not available (120 aa)
H920_13644Ig heavy chain V region M315. (122 aa)
LOC104872531Integrin alpha-M; Belongs to the integrin alpha chain family. (359 aa)
H920_07367Ig heavy chain V region M167. (113 aa)
H920_03480Ig heavy chain V-III region VH26. (176 aa)
MAPK11Mitogen-activated protein kinase 11. (325 aa)
H920_04309Ig heavy chain V region 1B43. (122 aa)
LOC104874234H-2 class II histocompatibility antigen, A beta chain. (337 aa)
ELK1ETS domain-containing protein Elk-1. (427 aa)
ENSFDAP00000009864annotation not available (322 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (967 aa)
Fcgr1aFc fragment of IgG receptor Ia. (374 aa)
H920_04300Ig heavy chain V-III region VH26. (143 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (254 aa)
H920_05759DLA class II histocompatibility antigen, DR-1 beta chain. (268 aa)
ENSFDAP00000009051annotation not available (385 aa)
LOC104874226HLA class II histocompatibility antigen, DQ alpha 1 chain; Belongs to the MHC class II family. (255 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
H920_13645Ig heavy chain V region M315. (120 aa)
H920_04299Ig heavy chain V region 1B43. (122 aa)
H920_04301Ig heavy chain V-II region SESS. (170 aa)
NOXA1NADPH oxidase activator 1. (532 aa)
H920_05193Integrin alpha-M. (252 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (839 aa)
HLA-DOBHLA class II histocompatibility antigen, DO beta chain. (301 aa)
NCF4Neutrophil cytosol factor 4. (340 aa)
RELATranscription factor p65. (545 aa)
PRKCBProtein kinase C beta type. (586 aa)
HLA-DMAHLA class II histocompatibility antigen, DM alpha chain; Belongs to the MHC class II family. (304 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
NCF2Neutrophil cytosol factor 2. (526 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (240 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
ENSFDAP00000004185annotation not available (148 aa)
EEF1A2Elongation factor 1-alpha 1. (430 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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