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| | EGC16723.1 | Prenyltransferase, UbiA family; COG: COG0382; Belongs to the UbiA prenyltransferase family. (295 aa) |
| | EGC16722.1 | Hypothetical protein; 1.14.99.36. (556 aa) |
| | cadC | Cadmium efflux system accessory protein; COG: COG0640. (122 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa) |
| | ubiE | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (247 aa) |
| | pdxB | 4-phosphoerythronate dehydrogenase; COG: COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (759 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (219 aa) |
| | EGC16926.1 | GIY-YIG catalytic domain protein. (85 aa) |
| | EGC16925.1 | Acetyltransferase, GNAT family. (279 aa) |
| | EGC16919.1 | Hypothetical protein. (106 aa) |
| | ywrO-2 | General stress protein 14; COG: COG2249. (195 aa) |
| | EGC16894.1 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG: COG0654. (407 aa) |
| | gpm | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (239 aa) |
| | thrC | Threonine synthase; COG: COG0498. (469 aa) |
| | argG | Argininosuccinate synthase; COG: COG0137; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (443 aa) |
| | tcmP | O-methyltransferase domain protein; COG: COG3315. (275 aa) |
| | purD | Phosphoribosylamine--glycine ligase; COG: COG0151; Belongs to the GARS family. (426 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (321 aa) |
| | gnd | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (482 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | ispA | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. (295 aa) |
| | ispB | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. (324 aa) |
| | EGC16930.1 | Hypothetical protein. (376 aa) |
| | EGC16972.1 | Hypothetical protein. (165 aa) |
| | ubiG | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (237 aa) |
| | hemL | Glutamate-1-semialdehyde-2,1-aminomutase; COG: COG0001. (427 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (406 aa) |
| | arsC | Arsenate reductase; COG: COG1393. (124 aa) |
| | trmD | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (251 aa) |
| | uppS | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa) |
| | cdsA-2 | Phosphatidate cytidylyltransferase; COG: COG0575; Belongs to the CDS family. (263 aa) |
| | hemB | Porphobilinogen synthase; COG: COG0113; Belongs to the ALAD family. (322 aa) |
| | EGC17088.1 | Chorismate mutase. (95 aa) |
| | suhB2 | Inositol monophosphatase family protein; COG: COG0483; Belongs to the inositol monophosphatase superfamily. (266 aa) |
| | ilvD | Dihydroxy-acid dehydratase; COG: COG0129; Belongs to the IlvD/Edd family. (619 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (311 aa) |
| | EGC17186.1 | Putative TIGR00701 family protein; COG: COG1981. (139 aa) |
| | maf-3 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (198 aa) |
| | EGC17181.1 | Purine/pyrimidine phosphoribosyltransferase family protein; COG: COG2236. (177 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (345 aa) |
| | corC | CBS domain protein; COG: COG4535. (280 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) |
| | maf-2 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (208 aa) |
| | tyrB | Aminotransferase, class I/II; COG: COG1448. (436 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (371 aa) |
| | EGC17136.1 | Hypothetical protein. (149 aa) |
| | EGC17122.1 | NmrA family protein; COG: COG0702. (306 aa) |
| | ribD | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (369 aa) |
| | gpsA | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (329 aa) |
| | EGC17341.1 | Cof-like hydrolase; COG: COG0561. (268 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | grpE | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] (186 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (480 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (413 aa) |
| | EGC17306.1 | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824. (137 aa) |
| | pssA | CDP-diacylglycerol-serine O-phosphatidyltransferase; COG: COG1183; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (273 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | lpdA-2 | Dihydrolipoyl dehydrogenase; COG: COG1249. (476 aa) |
| | maf | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (200 aa) |
| | metC | Cys/Met metabolism PLP-dependent enzyme; COG: COG0626. (384 aa) |
| | gpmB | Phosphoglycerate mutase family protein; COG: COG0406; Belongs to the phosphoglycerate mutase family. (220 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (333 aa) |
| | avtA | Aminotransferase, class I/II; COG: COG3977. (427 aa) |
| | glk | Glucokinase; COG: COG0837; Belongs to the bacterial glucokinase family. (326 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (240 aa) |
| | miaA | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (322 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (594 aa) |
| | cysK | Cysteine synthase A; COG: COG0031; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (635 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (356 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) |
| | EGC17418.1 | ABC transporter, substrate-binding protein, family 3; COG: COG0834; Belongs to the bacterial solute-binding protein 3 family. (272 aa) |
| | surE | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (304 aa) |
| | EGC17409.1 | Hypothetical protein; 2.5.1.54. (292 aa) |
| | tig | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (432 aa) |
| | EGC17435.1 | Hypothetical protein; COG: COG2833. (282 aa) |
| | hexR | SIS domain protein; COG: COG1737. (287 aa) |
| | pgi | Glucose-6-phosphate isomerase; COG: COG0166; Belongs to the GPI family. (557 aa) |
| | pgk | Phosphoglycerate kinase; COG: COG0126; Belongs to the phosphoglycerate kinase family. (444 aa) |
| | EGC17444.1 | Radical SAM domain protein; COG: COG0635. (610 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (260 aa) |
| | fbp | Fructose-1,6-bisphosphatase; COG: COG0158; Belongs to the FBPase class 1 family. (324 aa) |
| | acnB | Aconitate hydratase 2; COG: COG1049; Belongs to the aconitase/IPM isomerase family. (861 aa) |
| | htpX2 | Peptidase, M48 family; COG: COG0501; Belongs to the peptidase M48B family. (312 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (491 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (407 aa) |
| | hemX | HemX; COG: COG2959. (458 aa) |
| | hemD | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (245 aa) |
| | hemC | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (313 aa) |
| | EGC17635.1 | Acyltransferase. (377 aa) |
| | fabI | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0623. (279 aa) |
| | EGC17625.1 | Cysteine-rich domain protein; COG: COG0247. (256 aa) |
| | putA | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1223 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (213 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (402 aa) |
| | sucA | Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; COG: COG0567. (959 aa) |
| | ttcA | PP-loop family protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (323 aa) |
| | gph-2 | Phosphoglycolate phosphatase, bacterial; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (231 aa) |
| | EGC17580.1 | Rhodanese-like protein; COG: COG0607. (107 aa) |
| | lolB | Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. (204 aa) |
| | EGC17575.1 | Tetratricopeptide repeat protein; COG: COG0457. (642 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (430 aa) |
| | ribE | Riboflavin synthase, alpha subunit; COG: COG0307. (223 aa) |
| | argA | Amino-acid N-acetyltransferase; COG: COG0548; Belongs to the acetyltransferase family. ArgA subfamily. (437 aa) |
| | prmA | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (311 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | EGC16177.1 | Polyketide cyclase/dehydrase; COG: COG2867. (142 aa) |
| | metX | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (391 aa) |
| | trpG | Glutamine amidotransferase, class I; COG: COG0512. (195 aa) |
| | rfbB | dTDP-glucose 4,6-dehydratase; COG: COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (366 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (326 aa) |
| | rfbD-2 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (302 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa) |
| | pldA | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. (412 aa) |
| | algA | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family. (483 aa) |
| | plsC | Acyltransferase; COG: COG0204; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (256 aa) |
| | icd | Isocitrate dehydrogenase, NADP-dependent; COG: COG2838; Belongs to the monomeric-type IDH family. (740 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (139 aa) |
| | dgkA | Prokaryotic diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (124 aa) |
| | ilvE | Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (314 aa) |
| | EGC16210.1 | Universal stress family protein; COG: COG0589. (200 aa) |
| | ppsA | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (798 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (208 aa) |
| | hpnC | Squalene synthase HpnC; COG: COG1562. (272 aa) |
| | EGC16189.1 | Hypothetical protein; COG: COG0628. (358 aa) |
| | purB | Adenylosuccinate lyase; COG: COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa) |
| | EGC16293.1 | Methyltransferase domain protein. (201 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (432 aa) |
| | mdmC | O-methyltransferase; COG: COG4122. (222 aa) |
| | pyk | Pyruvate kinase; COG: COG0469; Belongs to the pyruvate kinase family. (490 aa) |
| | aroA2 | Prephenate dehydrogenase; COG: COG0287. (291 aa) |
| | mltB | Lytic murein transglycosylase B; COG: COG2951. (365 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (313 aa) |
| | EGC16416.1 | Putative toxin-antitoxin system, toxin component, PIN family. (83 aa) |
| | EGC16407.1 | Hypothetical protein. (64 aa) |
| | pivNM | Transposase; COG: COG3547. (225 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (300 aa) |
| | mgtE | Magnesium transporter; Acts as a magnesium transporter. (475 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (466 aa) |
| | pheA | Chorismate mutase; COG: COG0077. (398 aa) |
| | trpF | N-(5'phosphoribosyl)anthranilate isomerase; COG: COG0135; Belongs to the TrpF family. (206 aa) |
| | hpnD | Squalene synthase HpnD; COG: COG1562. (283 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (375 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (153 aa) |
| | ans | Asparaginase; COG: COG0252. (314 aa) |
| | aldA | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Belongs to the aldehyde dehydrogenase family. (491 aa) |
| | EGC17914.1 | Flavodoxin-like protein; COG: COG2249. (191 aa) |
| | ubiD | UbiD family decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (494 aa) |
| | EGC17912.1 | Hypothetical protein; COG: COG0702. (240 aa) |
| | yhxB | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109. (550 aa) |
| | EGC17884.1 | Endoribonuclease L-PSP. (394 aa) |
| | ubiA | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (326 aa) |
| | EGC17867.1 | BolA-like protein; Belongs to the BolA/IbaG family. (92 aa) |
| | thrA | Homoserine dehydrogenase; COG: COG0460. (435 aa) |
| | EGC17841.1 | Acetyltransferase, GNAT family; COG: COG1247. (166 aa) |
| | EGC17830.1 | Transcriptional regulator, Spx/MgsR family; COG: COG1393; Belongs to the ArsC family. (149 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; COG: COG0150. (345 aa) |
| | EGC17941.1 | Hypothetical protein. (369 aa) |
| | hisE | phosphoribosyl-ATP diphosphatase; COG: COG0139; In the N-terminal section; belongs to the PRA-CH family. (216 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; COG: COG0106. (249 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (199 aa) |
| | hisB | Histidinol-phosphatase; COG: COG0131; In the N-terminal section; belongs to the histidinol- phosphatase family. (362 aa) |
| | hisC-2 | Histidinol-phosphate transaminase; COG: COG0079; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (352 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (299 aa) |
| | tniB | Bacterial TniB protein. (297 aa) |
| | EGC18048.1 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG3967; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (283 aa) |
| | rpiB | Sugar-phosphate isomerase, RpiB/LacA/LacB family; COG: COG0698. (162 aa) |
| | EGC18033.1 | Hypothetical protein. (135 aa) |
| | EGC18028.1 | Hypothetical protein. (261 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (389 aa) |
| | hisC | Putative histidinol-phosphate transaminase; COG: COG0079. (424 aa) |
| | thrB | Homoserine kinase; COG: COG2334; Belongs to the pseudomonas-type ThrB family. (319 aa) |
| | gltA | Citrate (Si)-synthase; COG: COG0372; Belongs to the citrate synthase family. (427 aa) |
| | EGC17987.1 | TPR repeat region. (82 aa) |
| | sdhB | Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG: COG0479; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (234 aa) |
| | sdhA | Succinate dehydrogenase, flavoprotein subunit; COG: COG1053; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (586 aa) |
| | sdhD | Succinate dehydrogenase, hydrophobic membrane anchor protein; COG: COG2142. (132 aa) |
| | sdhC | Succinate dehydrogenase, cytochrome b556 subunit; COG: COG2009. (127 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (283 aa) |
| | serB | Phosphoserine phosphatase SerB; COG: COG0560. (276 aa) |
| | suhB | Inositol monophosphatase family protein; COG: COG0483. (264 aa) |
| | EGC18329.1 | ADP-ribosylglycohydrolase. (327 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (297 aa) |
| | EGC18293.1 | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG0633. (106 aa) |
| | EGC18292.1 | Hypothetical protein. (165 aa) |
| | EGC18278.1 | ResB-like protein; COG: COG1333. (655 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; COG: COG0036; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (357 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (263 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138. (576 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa) |
| | anmK | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (367 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (364 aa) |
| | ywrO | Flavodoxin-like protein; COG: COG2249. (183 aa) |
| | EGC18210.1 | Phosphoglycerate mutase family protein. (231 aa) |
| | EGC18181.1 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (405 aa) |
| | EGC18180.1 | ACT domain protein; COG: COG3830; Belongs to the UPF0237 family. (90 aa) |
| | EGC18179.1 | Hypothetical protein. (286 aa) |
| | draG | ADP-ribosylglycohydrolase. (330 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; COG: COG0134; Belongs to the TrpC family. (261 aa) |
| | gluQ | Glutamyl-queuosine tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (299 aa) |
| | efeU | FTR1 family protein; COG: COG0672. (282 aa) |
| | rfbD | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (313 aa) |
| | prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (342 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Belongs to the SAICAR synthetase family. (288 aa) |
| | ilvN | Acetolactate synthase, small subunit; COG: COG0440. (163 aa) |
| | ilvB | Acetolactate synthase, large subunit, biosynthetic type; COG: COG0028. (594 aa) |
| | ubiX | Putative aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (294 aa) |
| | aceE | Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (897 aa) |
| | aceF | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (571 aa) |
| | cat | Succinate CoA transferase; COG: COG0427. (506 aa) |
| | lysC | Aspartate kinase, monofunctional class; COG: COG0527; Belongs to the aspartokinase family. (426 aa) |
| | EGC18078.1 | FxsA cytoplasmic membrane protein. (180 aa) |
| | EGC18074.1 | FAD dependent oxidoreductase. (401 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (399 aa) |
| | lpdA | Dihydrolipoyl dehydrogenase; COG: COG1249. (618 aa) |
| | EGC18394.1 | Hypothetical protein. (283 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (421 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (144 aa) |
| | ilvA | Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (512 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (312 aa) |
| | EGC18494.1 | SCO1/SenC; COG: COG1999. (241 aa) |
| | EGC18485.1 | Hypothetical protein. (64 aa) |
| | EGC18478.1 | Acyltransferase; COG: COG0204. (225 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; COG: COG4589. (317 aa) |
| | hemN | Coproporphyrinogen dehydrogenase; COG: COG0635; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (505 aa) |
| | plsY | Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (201 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (510 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (368 aa) |
| | EGC18457.1 | Hypothetical protein. (176 aa) |
| | EGC18450.1 | Acyltransferase; COG: COG1835. (642 aa) |
| | ispE | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (285 aa) |
| | deoD | Purine nucleoside phosphorylase; COG: COG0813. (237 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (360 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (177 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (301 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (422 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (659 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1298 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (413 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | cysE | Serine O-acetyltransferase; COG: COG1045. (266 aa) |
| | fabG | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | fabD | [acyl-carrier-protein] S-malonyltransferase; COG: COG0331. (322 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (356 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (278 aa) |
| | fba | Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (369 aa) |
| | EGC16338.1 | Transcriptional regulator, ArsR family. (103 aa) |
| | aroG | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (349 aa) |
| | ribB | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (362 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa) |
| | hdtS | Acyltransferase; COG: COG0204. (243 aa) |
| | map | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (258 aa) |
| | EGC16532.1 | Methyltransferase domain protein. (249 aa) |
| | EGC16527.1 | Hypothetical protein. (112 aa) |
| | EGC16526.1 | Hypothetical protein. (123 aa) |
| | EGC16522.1 | Zinc-binding alcohol dehydrogenase family protein; COG: COG0604; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (338 aa) |
| | linC | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028. (253 aa) |
| | EGC16443.1 | Hypothetical protein. (168 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (416 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (325 aa) |
| | gidA | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1249. (469 aa) |
| | argH | Argininosuccinate lyase; COG: COG0165. (463 aa) |
| | galU | UTP--glucose-1-phosphate uridylyltransferase; COG: COG1210. (295 aa) |
| | EGC16588.1 | Hypothetical protein; COG: COG0331; 2.3.1.85. (344 aa) |
| | EGC16579.1 | Transporter associated domain protein. (519 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; COG: COG0196. (365 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa) |
| | rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (242 aa) |
| | EGC16569.1 | Nuclease-like protein; COG: COG1525. (180 aa) |
| | argJ | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (405 aa) |
| | fumB | Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa) |
| | yhhQ | Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (232 aa) |
| | tyrB2 | Aminotransferase, class I/II; COG: COG1448. (442 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (231 aa) |
| | adhP | GroES-like protein; COG: COG1064. (355 aa) |
| | EGC16726.1 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028. (251 aa) |
