STRINGSTRING
AFG36176.1 AFG36176.1 AFG36450.1 AFG36450.1 murG murG AFG36871.1 AFG36871.1 AFG37070.1 AFG37070.1 AFG37479.1 AFG37479.1 AFG37501.1 AFG37501.1 AFG37562.1 AFG37562.1 AFG37563.1 AFG37563.1 AFG37564.1 AFG37564.1 AFG37565.1 AFG37565.1 AFG37566.1 AFG37566.1 rodA rodA murE murE ddl ddl AFG37966.1 AFG37966.1 AFG38079.1 AFG38079.1 AFG38115.1 AFG38115.1 xerC-2 xerC-2 ftsZ ftsZ ftsA ftsA AFG38166.1 AFG38166.1 AFG38167.1 AFG38167.1 mraY mraY murF murF AFG38170.1 AFG38170.1 rsmH rsmH mraZ mraZ AFG38290.1 AFG38290.1 murC murC murB murB AFG38770.1 AFG38770.1 murA murA AFG38839.1 AFG38839.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFG36176.1UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: Glycosyl transferase family 4. (369 aa)
AFG36450.1Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family. (815 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (369 aa)
AFG36871.1Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. (630 aa)
AFG37070.1PFAM: D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (431 aa)
AFG37479.1UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (464 aa)
AFG37501.1PFAM: D-alanyl-D-alanine carboxypeptidase. (280 aa)
AFG37562.1Tfp pilus assembly protein PilF; PFAM: Tetratricopeptide repeat. (313 aa)
AFG37563.1PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family. (340 aa)
AFG37564.1Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (288 aa)
AFG37565.1PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD. (168 aa)
AFG37566.1Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2. (623 aa)
rodARod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (441 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (507 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (358 aa)
AFG37966.1Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family. (884 aa)
AFG38079.1Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23. (306 aa)
AFG38115.1tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (324 aa)
xerC-2Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (309 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (391 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (411 aa)
AFG38166.1Cell division septal protein; Essential cell division protein. (301 aa)
AFG38167.1PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. (380 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (359 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (466 aa)
AFG38170.1Hypothetical protein. (93 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (317 aa)
mraZPFAM: MraZ protein; TIGRFAM: mraZ protein; manually curated; Belongs to the MraZ family. (147 aa)
AFG38290.1Transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. Belongs to the glycosyltransferase 51 family. (788 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (481 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (317 aa)
AFG38770.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (392 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (430 aa)
AFG38839.1Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23. (393 aa)
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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