STRINGSTRING
AFG36122.1 AFG36122.1 AFG36224.1 AFG36224.1 AFG36228.1 AFG36228.1 AFG36265.1 AFG36265.1 AFG36298.1 AFG36298.1 AFG36315.1 AFG36315.1 AFG36325.1 AFG36325.1 AFG36347.1 AFG36347.1 AFG36360.1 AFG36360.1 AFG36361.1 AFG36361.1 AFG36388.1 AFG36388.1 AFG36398.1 AFG36398.1 AFG36413.1 AFG36413.1 AFG36424.1 AFG36424.1 AFG36447.1 AFG36447.1 AFG36455.1 AFG36455.1 AFG36459.1 AFG36459.1 AFG36466.1 AFG36466.1 AFG36467.1 AFG36467.1 AFG36472.1 AFG36472.1 AFG36549.1 AFG36549.1 AFG36586.1 AFG36586.1 AFG36590.1 AFG36590.1 AFG36614.1 AFG36614.1 AFG36624.1 AFG36624.1 AFG36709.1 AFG36709.1 AFG36743.1 AFG36743.1 AFG36744.1 AFG36744.1 AFG36768.1 AFG36768.1 AFG36810.1 AFG36810.1 AFG36811.1 AFG36811.1 AFG36820.1 AFG36820.1 AFG36827.1 AFG36827.1 AFG36829.1 AFG36829.1 AFG36835.1 AFG36835.1 AFG36913.1 AFG36913.1 AFG36929.1 AFG36929.1 AFG36931.1 AFG36931.1 AFG36932.1 AFG36932.1 AFG36933.1 AFG36933.1 AFG36943.1 AFG36943.1 AFG37011.1 AFG37011.1 AFG37039.1 AFG37039.1 AFG37040.1 AFG37040.1 AFG37072.1 AFG37072.1 AFG37078.1 AFG37078.1 AFG37153.1 AFG37153.1 AFG37190.1 AFG37190.1 AFG37191.1 AFG37191.1 AFG37281.1 AFG37281.1 AFG37297.1 AFG37297.1 AFG37307.1 AFG37307.1 AFG37332.1 AFG37332.1 AFG37366.1 AFG37366.1 AFG37392.1 AFG37392.1 AFG37403.1 AFG37403.1 AFG37404.1 AFG37404.1 AFG37407.1 AFG37407.1 AFG37763.1 AFG37763.1 AFG37768.1 AFG37768.1 AFG37784.1 AFG37784.1 AFG37785.1 AFG37785.1 AFG37803.1 AFG37803.1 AFG37827.1 AFG37827.1 AFG37831.1 AFG37831.1 AFG37868.1 AFG37868.1 AFG37870.1 AFG37870.1 AFG37920.1 AFG37920.1 AFG37978.1 AFG37978.1 AFG37992.1 AFG37992.1 AFG38113.1 AFG38113.1 AFG38206.1 AFG38206.1 AFG38212.1 AFG38212.1 AFG38216.1 AFG38216.1 AFG38270.1 AFG38270.1 AFG38279.1 AFG38279.1 AFG38337.1 AFG38337.1 AFG38348.1 AFG38348.1 AFG38349.1 AFG38349.1 AFG38398.1 AFG38398.1 AFG38405.1 AFG38405.1 AFG38407.1 AFG38407.1 AFG38408.1 AFG38408.1 AFG38409.1 AFG38409.1 AFG38415.1 AFG38415.1 AFG38416.1 AFG38416.1 AFG38555.1 AFG38555.1 AFG38793.1 AFG38793.1 AFG38810.1 AFG38810.1 AFG38850.1 AFG38850.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFG36122.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (993 aa)
AFG36224.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (369 aa)
AFG36228.1PAS domain S-box; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. (529 aa)
AFG36265.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold. (818 aa)
AFG36298.1PFAM: Adenylate and Guanylate cyclase catalytic domain. (631 aa)
AFG36315.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (819 aa)
AFG36325.1CheY-like receiver domain-containing protein; PFAM: Response regulator receiver domain. (121 aa)
AFG36347.1PAS domain S-box; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box. (1221 aa)
AFG36360.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain. (745 aa)
AFG36361.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (298 aa)
AFG36388.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (642 aa)
AFG36398.1PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (588 aa)
AFG36413.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (369 aa)
AFG36424.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (535 aa)
AFG36447.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (498 aa)
AFG36455.1Response regulator containing a CheY-like receiver domain and an HD-GYP domain; PFAM: HD domain. (591 aa)
AFG36459.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (445 aa)
AFG36466.1HPt domain-containing protein; PFAM: Hpt domain. (116 aa)
AFG36467.1PFAM: Y_Y_Y domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller; His Kinase A (phosphoacceptor) domain; Hpt domain. (1509 aa)
AFG36472.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (398 aa)
AFG36549.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (499 aa)
AFG36586.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain. (424 aa)
AFG36590.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (474 aa)
AFG36614.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (618 aa)
AFG36624.1HPt domain-containing protein; PFAM: Hpt domain. (111 aa)
AFG36709.1PFAM: Ammonium Transporter Family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain; TIGRFAM: ammonium transporter. (934 aa)
AFG36743.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold. (586 aa)
AFG36744.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (228 aa)
AFG36768.1PFAM: Response regulator receiver domain; TIGRFAM: DNA binding domain, excisionase family. (211 aa)
AFG36810.1PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (338 aa)
AFG36811.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (883 aa)
AFG36820.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (369 aa)
AFG36827.1PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (627 aa)
AFG36829.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain. (993 aa)
AFG36835.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Bacterial extracellular solute-binding proteins, family 3; PAS fold; TIGRFAM: PAS domain S-box. (714 aa)
AFG36913.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Cyclic nucleotide-binding domain. (389 aa)
AFG36929.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (351 aa)
AFG36931.1TIGRFAM: PAS domain S-box. (116 aa)
AFG36932.1PFAM: GAF domain; PAS fold; TIGRFAM: PAS domain S-box. (370 aa)
AFG36933.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; Hpt domain; TIGRFAM: PAS domain S-box. (804 aa)
AFG36943.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (955 aa)
AFG37011.1PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (671 aa)
AFG37039.1PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (223 aa)
AFG37040.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (459 aa)
AFG37072.1PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (437 aa)
AFG37078.1PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (630 aa)
AFG37153.1PFAM: Response regulator receiver domain. (133 aa)
AFG37190.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (383 aa)
AFG37191.1PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (621 aa)
AFG37281.1EAL domain-containing protein; PFAM: EAL domain. (418 aa)
AFG37297.1HD-GYP domain-containing protein; PFAM: HD domain. (378 aa)
AFG37307.1Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; PFAM: Bacterial regulatory proteins, luxR family. (231 aa)
AFG37332.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (490 aa)
AFG37366.1PFAM: 7TM diverse intracellular signalling; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (587 aa)
AFG37392.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (292 aa)
AFG37403.1PFAM: EAL domain; Domain of unknown function (DUF3369); GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (755 aa)
AFG37404.1Signal transduction histidine kinase regulating C4-dicarboxylate transport system; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (659 aa)
AFG37407.1PFAM: Response regulator receiver domain. (173 aa)
AFG37763.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (945 aa)
AFG37768.1PFAM: Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller. (1073 aa)
AFG37784.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box. (792 aa)
AFG37785.1PFAM: Response regulator receiver domain. (412 aa)
AFG37803.1PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (700 aa)
AFG37827.1EAL domain-containing protein; PFAM: EAL domain; Response regulator receiver domain. (556 aa)
AFG37831.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (135 aa)
AFG37868.1PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain. (696 aa)
AFG37870.1PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; manually curated. (568 aa)
AFG37920.1Histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold. (501 aa)
AFG37978.1HD-GYP domain-containing protein; PFAM: HD domain. (391 aa)
AFG37992.1PFAM: Response regulator receiver domain. (247 aa)
AFG38113.1PFAM: Response regulator receiver domain. (129 aa)
AFG38206.1PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (623 aa)
AFG38212.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (372 aa)
AFG38216.1PAS domain S-box; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box. (607 aa)
AFG38270.1PAS domain S-box; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; Bacterial extracellular solute-binding proteins, family 3; PAS fold; TIGRFAM: PAS domain S-box. (1031 aa)
AFG38279.1PAS domain S-box; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: PAS domain S-box. (623 aa)
AFG38337.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (963 aa)
AFG38348.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (243 aa)
AFG38349.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (449 aa)
AFG38398.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (479 aa)
AFG38405.1PFAM: 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; 7TMR-DISM extracellular 2; His Kinase A (phosphoacceptor) domain. (866 aa)
AFG38407.1Hypothetical protein. (103 aa)
AFG38408.1PFAM: Response regulator receiver domain. (124 aa)
AFG38409.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain. (419 aa)
AFG38415.1PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (335 aa)
AFG38416.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (519 aa)
AFG38555.1EAL domain-containing protein; PFAM: EAL domain. (352 aa)
AFG38793.1Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain; PFAM: Transcriptional regulatory protein, C terminal. (195 aa)
AFG38810.1Response regulator containing a CheY-like receiver domain and an HD-GYP domain; PFAM: HD domain; GAF domain. (409 aa)
AFG38850.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain. (408 aa)
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.