STRINGSTRING
mutL mutL AFG37728.1 AFG37728.1 AFG37763.1 AFG37763.1 AFG37768.1 AFG37768.1 AFG37784.1 AFG37784.1 AFG37803.1 AFG37803.1 AFG37914.1 AFG37914.1 AFG37920.1 AFG37920.1 AFG37924.1 AFG37924.1 AFG38102.1 AFG38102.1 AFG38123.1 AFG38123.1 AFG38212.1 AFG38212.1 AFG38216.1 AFG38216.1 AFG38270.1 AFG38270.1 AFG38279.1 AFG38279.1 AFG38337.1 AFG38337.1 AFG38349.1 AFG38349.1 AFG38398.1 AFG38398.1 AFG38405.1 AFG38405.1 AFG38406.1 AFG38406.1 AFG38409.1 AFG38409.1 AFG38416.1 AFG38416.1 AFG38432.1 AFG38432.1 AFG38437.1 AFG38437.1 AFG38498.1 AFG38498.1 htpG htpG AFG38673.1 AFG38673.1 AFG38692.1 AFG38692.1 AFG38708.1 AFG38708.1 AFG38712.1 AFG38712.1 gyrB gyrB AFG38850.1 AFG38850.1 AFG36213.1 AFG36213.1 AFG36228.1 AFG36228.1 AFG36257.1 AFG36257.1 AFG36265.1 AFG36265.1 AFG36315.1 AFG36315.1 AFG36324.1 AFG36324.1 AFG36335.1 AFG36335.1 AFG36347.1 AFG36347.1 AFG36360.1 AFG36360.1 AFG36361.1 AFG36361.1 AFG36379.1 AFG36379.1 AFG36388.1 AFG36388.1 AFG36398.1 AFG36398.1 AFG36436.1 AFG36436.1 AFG36459.1 AFG36459.1 AFG36467.1 AFG36467.1 AFG36472.1 AFG36472.1 AFG36483.1 AFG36483.1 AFG36531.1 AFG36531.1 AFG36586.1 AFG36586.1 AFG36590.1 AFG36590.1 AFG36614.1 AFG36614.1 AFG36692.1 AFG36692.1 AFG36709.1 AFG36709.1 AFG36714.1 AFG36714.1 AFG36743.1 AFG36743.1 AFG36811.1 AFG36811.1 AFG36829.1 AFG36829.1 AFG36835.1 AFG36835.1 AFG36850.1 AFG36850.1 AFG36913.1 AFG36913.1 AFG36933.1 AFG36933.1 AFG37001.1 AFG37001.1 AFG37040.1 AFG37040.1 AFG37072.1 AFG37072.1 AFG37073.1 AFG37073.1 AFG37190.1 AFG37190.1 AFG37332.1 AFG37332.1 AFG37404.1 AFG37404.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (611 aa)
AFG37728.1Chemotaxis protein histidine kinase-like protein; PFAM: P2 response regulator binding domain; CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain. (806 aa)
AFG37763.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (945 aa)
AFG37768.1PFAM: Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller. (1073 aa)
AFG37784.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box. (792 aa)
AFG37803.1PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (700 aa)
AFG37914.1Chemotaxis protein histidine kinase-like protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain. (662 aa)
AFG37920.1Histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold. (501 aa)
AFG37924.1Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain. (726 aa)
AFG38102.1Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus. (609 aa)
AFG38123.1Chemotaxis protein histidine kinase-like protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain. (584 aa)
AFG38212.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (372 aa)
AFG38216.1PAS domain S-box; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box. (607 aa)
AFG38270.1PAS domain S-box; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; Bacterial extracellular solute-binding proteins, family 3; PAS fold; TIGRFAM: PAS domain S-box. (1031 aa)
AFG38279.1PAS domain S-box; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: PAS domain S-box. (623 aa)
AFG38337.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (963 aa)
AFG38349.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (449 aa)
AFG38398.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (479 aa)
AFG38405.1PFAM: 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; 7TMR-DISM extracellular 2; His Kinase A (phosphoacceptor) domain. (866 aa)
AFG38406.1Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain. (699 aa)
AFG38409.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain. (419 aa)
AFG38416.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (519 aa)
AFG38432.1Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (311 aa)
AFG38437.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (194 aa)
AFG38498.1PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (601 aa)
htpGMolecular chaperone of HSP90 family; Molecular chaperone. Has ATPase activity. (630 aa)
AFG38673.1Anti-sigma regulatory factor (Ser/Thr protein kinase); PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (184 aa)
AFG38692.1Histidine kinase,HAMP domain-containing protein,histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (584 aa)
AFG38708.1PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (567 aa)
AFG38712.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (297 aa)
gyrBType IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA stran [...] (636 aa)
AFG38850.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain. (408 aa)
AFG36213.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (164 aa)
AFG36228.1PAS domain S-box; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. (529 aa)
AFG36257.1Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain. (681 aa)
AFG36265.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold. (818 aa)
AFG36315.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (819 aa)
AFG36324.1PAS domain S-box; PFAM: CheB methylesterase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CheR methyltransferase, SAM binding domain; His Kinase A (phosphoacceptor) domain; CheR methyltransferase, all-alpha domain; PAS fold; TIGRFAM: PAS domain S-box. (1584 aa)
AFG36335.1Putative domain HDIG-containing protein; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG. (492 aa)
AFG36347.1PAS domain S-box; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box. (1221 aa)
AFG36360.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain. (745 aa)
AFG36361.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (298 aa)
AFG36379.1PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (503 aa)
AFG36388.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (642 aa)
AFG36398.1PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (588 aa)
AFG36436.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (454 aa)
AFG36459.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (445 aa)
AFG36467.1PFAM: Y_Y_Y domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller; His Kinase A (phosphoacceptor) domain; Hpt domain. (1509 aa)
AFG36472.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (398 aa)
AFG36483.1PFAM: Cyclic nucleotide-binding domain. (435 aa)
AFG36531.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (462 aa)
AFG36586.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain. (424 aa)
AFG36590.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (474 aa)
AFG36614.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (618 aa)
AFG36692.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (391 aa)
AFG36709.1PFAM: Ammonium Transporter Family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain; TIGRFAM: ammonium transporter. (934 aa)
AFG36714.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Cyclic nucleotide-binding domain. (429 aa)
AFG36743.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold. (586 aa)
AFG36811.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (883 aa)
AFG36829.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain. (993 aa)
AFG36835.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Bacterial extracellular solute-binding proteins, family 3; PAS fold; TIGRFAM: PAS domain S-box. (714 aa)
AFG36850.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (467 aa)
AFG36913.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Cyclic nucleotide-binding domain. (389 aa)
AFG36933.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; Hpt domain; TIGRFAM: PAS domain S-box. (804 aa)
AFG37001.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold. (712 aa)
AFG37040.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (459 aa)
AFG37072.1PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (437 aa)
AFG37073.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (586 aa)
AFG37190.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (383 aa)
AFG37332.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (490 aa)
AFG37404.1Signal transduction histidine kinase regulating C4-dicarboxylate transport system; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (659 aa)
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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