STRINGSTRING
AFG36194.1 AFG36194.1 fabH fabH AFG36355.1 AFG36355.1 AFG36356.1 AFG36356.1 AFG36357.1 AFG36357.1 AFG37013.1 AFG37013.1 AFG37377.1 AFG37377.1 AFG37378.1 AFG37378.1 AFG37476.1 AFG37476.1 fabV fabV AFG37541.1 AFG37541.1 AFG37767.1 AFG37767.1 AFG37818.1 AFG37818.1 AFG37825.1 AFG37825.1 accA accA accD accD AFG38249.1 AFG38249.1 AFG38250.1 AFG38250.1 AFG38251.1 AFG38251.1 AFG38315.1 AFG38315.1 AFG38316.1 AFG38316.1 AFG38317.1 AFG38317.1 AFG38318.1 AFG38318.1 AFG38319.1 AFG38319.1 AFG38796.1 AFG38796.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFG36194.1AMP-forming long-chain acyl-CoA synthetase; PFAM: AMP-binding enzyme. (645 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (346 aa)
AFG36355.1PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase. (313 aa)
AFG36356.13-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa)
AFG36357.1Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (419 aa)
AFG37013.1AMP-forming long-chain acyl-CoA synthetase; PFAM: AMP-binding enzyme. (538 aa)
AFG37377.1acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: AMP-binding enzyme. (299 aa)
AFG37378.1acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: AMP-binding enzyme. (470 aa)
AFG37476.1Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase. (251 aa)
fabVPutative paraquat-inducible protein B; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA); Belongs to the TER reductase family. (399 aa)
AFG37541.1PFAM: Acyl-ACP thioesterase. (247 aa)
AFG37767.1AMP-forming long-chain acyl-CoA synthetase; PFAM: AMP-binding enzyme. (559 aa)
AFG37818.1acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme; TIGRFAM: 4-coumarate--CoA ligase, photoactive yellow protein activation family. (365 aa)
AFG37825.1AMP-forming long-chain acyl-CoA synthetase; PFAM: AMP-binding enzyme. (578 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa)
AFG38249.1acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit. (439 aa)
AFG38250.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (172 aa)
AFG38251.1PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ. (140 aa)
AFG38315.1Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase. (315 aa)
AFG38316.1PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III. (342 aa)
AFG38317.13-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; PFAM: FabA-like domain. (194 aa)
AFG38318.13-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; PFAM: FabA-like domain. (158 aa)
AFG38319.1PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (429 aa)
AFG38796.1Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase. (261 aa)
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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