STRINGSTRING
gcvH gcvH metK metK AFG36139.1 AFG36139.1 AFG36140.1 AFG36140.1 AFG36148.1 AFG36148.1 AFG36190.1 AFG36190.1 lysA lysA purL purL AFG36198.1 AFG36198.1 AFG36210.1 AFG36210.1 AFG36218.1 AFG36218.1 AFG36219.1 AFG36219.1 AFG36229.1 AFG36229.1 AFG36235.1 AFG36235.1 AFG36236.1 AFG36236.1 AFG36237.1 AFG36237.1 AFG36239.1 AFG36239.1 sucD sucD AFG36246.1 AFG36246.1 AFG36275.1 AFG36275.1 pgi pgi argG argG AFG36301.1 AFG36301.1 AFG36302.1 AFG36302.1 argC argC zwf zwf AFG36321.1 AFG36321.1 AFG36350.1 AFG36350.1 AFG36355.1 AFG36355.1 AFG36356.1 AFG36356.1 AFG36368.1 AFG36368.1 AFG36396.1 AFG36396.1 pgl pgl AFG36411.1 AFG36411.1 AFG36412.1 AFG36412.1 AFG36431.1 AFG36431.1 gpsA gpsA ndk ndk aroK aroK AFG36462.1 AFG36462.1 AFG36465.1 AFG36465.1 AFG36477.1 AFG36477.1 AFG36479.1 AFG36479.1 AFG36480.1 AFG36480.1 fni fni AFG36482.1 AFG36482.1 AFG36499.1 AFG36499.1 AFG36515.1 AFG36515.1 metAA metAA rpiA rpiA purC purC AFG36569.1 AFG36569.1 AFG36578.1 AFG36578.1 purK purK purE purE AFG36584.1 AFG36584.1 pfkA pfkA AFG36593.1 AFG36593.1 AFG36625.1 AFG36625.1 ilvC ilvC gpmI gpmI AFG36641.1 AFG36641.1 AFG36695.1 AFG36695.1 AFG36696.1 AFG36696.1 AFG36722.1 AFG36722.1 AFG36750.1 AFG36750.1 eno eno AFG36776.1 AFG36776.1 AFG36777.1 AFG36777.1 AFG36778.1 AFG36778.1 AFG36788.1 AFG36788.1 AFG36789.1 AFG36789.1 AFG36790.1 AFG36790.1 AFG36793.1 AFG36793.1 ilvA ilvA AFG36867.1 AFG36867.1 AFG36869.1 AFG36869.1 AFG36881.1 AFG36881.1 glgA glgA ribA ribA AFG36923.1 AFG36923.1 AFG36982.1 AFG36982.1 AFG36983.1 AFG36983.1 hisC hisC AFG37077.1 AFG37077.1 AFG37082.1 AFG37082.1 AFG37109.1 AFG37109.1 AFG37134.1 AFG37134.1 AFG37140.1 AFG37140.1 AFG37152.1 AFG37152.1 miaA miaA AFG37175.1 AFG37175.1 AFG37192.1 AFG37192.1 AFG37221.1 AFG37221.1 AFG37235.1 AFG37235.1 AFG37251.1 AFG37251.1 pfp pfp AFG37253.1 AFG37253.1 AFG37258.1 AFG37258.1 AFG37266.1 AFG37266.1 AFG37272.1 AFG37272.1 AFG37273.1 AFG37273.1 AFG37304.1 AFG37304.1 AFG37312.1 AFG37312.1 AFG37339.1 AFG37339.1 AFG37343.1 AFG37343.1 AFG37346.1 AFG37346.1 AFG37353.1 AFG37353.1 AFG37358.1 AFG37358.1 AFG37360.1 AFG37360.1 ribH ribH ribB ribB AFG37398.1 AFG37398.1 AFG37399.1 AFG37399.1 asnA asnA AFG37414.1 AFG37414.1 AFG37476.1 AFG37476.1 hisD hisD fabV fabV AFG37544.1 AFG37544.1 AFG37553.1 AFG37553.1 AFG37581.1 AFG37581.1 AFG37585.1 AFG37585.1 AFG37596.1 AFG37596.1 AFG37618.1 AFG37618.1 guaB guaB AFG37669.1 AFG37669.1 AFG37674.1 AFG37674.1 tpiA tpiA pgk pgk AFG37691.1 AFG37691.1 AFG37718.1 AFG37718.1 AFG37719.1 AFG37719.1 AFG37721.1 AFG37721.1 AFG37722.1 AFG37722.1 ilvD ilvD acpP acpP AFG37760.1 AFG37760.1 dapL dapL AFG37795.1 AFG37795.1 AFG37840.1 AFG37840.1 AFG37857.1 AFG37857.1 AFG37858.1 AFG37858.1 AFG37859.1 AFG37859.1 pdhA pdhA AFG37869.1 AFG37869.1 aroK-2 aroK-2 proC proC AFG37943.1 AFG37943.1 AFG37944.1 AFG37944.1 AFG37948.1 AFG37948.1 gltX gltX AFG37976.1 AFG37976.1 surE surE purF purF purM purM purN purN purD purD AFG38034.1 AFG38034.1 AFG38039.1 AFG38039.1 AFG38040.1 AFG38040.1 AFG38051.1 AFG38051.1 argH argH AFG38077.1 AFG38077.1 AFG38088.1 AFG38088.1 AFG38093.1 AFG38093.1 AFG38096.1 AFG38096.1 proA proA proB proB AFG38100.1 AFG38100.1 AFG38101.1 AFG38101.1 AFG38173.1 AFG38173.1 AFG38184.1 AFG38184.1 adk adk AFG38195.1 AFG38195.1 AFG38207.1 AFG38207.1 AFG38232.1 AFG38232.1 dapB dapB dapA dapA accA accA accD accD AFG38249.1 AFG38249.1 AFG38250.1 AFG38250.1 AFG38265.1 AFG38265.1 AFG38266.1 AFG38266.1 hisB hisB AFG38278.1 AFG38278.1 AFG38298.1 AFG38298.1 AFG38304.1 AFG38304.1 AFG38305.1 AFG38305.1 AFG38315.1 AFG38315.1 AFG38320.1 AFG38320.1 AFG38323.1 AFG38323.1 ldh ldh AFG38334.1 AFG38334.1 leuC leuC AFG38377.1 AFG38377.1 AFG38380.1 AFG38380.1 AFG38383.1 AFG38383.1 AFG38389.1 AFG38389.1 trpB trpB ilvD-2 ilvD-2 leuA leuA AFG38447.1 AFG38447.1 pfkA-2 pfkA-2 AFG38482.1 AFG38482.1 AFG38496.1 AFG38496.1 AFG38500.1 AFG38500.1 AFG38503.1 AFG38503.1 hisF hisF hisH hisH glyA glyA AFG38523.1 AFG38523.1 AFG38533.1 AFG38533.1 AFG38535.1 AFG38535.1 AFG38551.1 AFG38551.1 AFG38552.1 AFG38552.1 argJ argJ AFG38576.1 AFG38576.1 trpA trpA trpB-2 trpB-2 trpD trpD trpE trpE AFG38592.1 AFG38592.1 AFG38618.1 AFG38618.1 AFG38631.1 AFG38631.1 AFG38653.1 AFG38653.1 aroA aroA AFG38669.1 AFG38669.1 AFG38680.1 AFG38680.1 serC serC AFG38728.1 AFG38728.1 AFG38731.1 AFG38731.1 AFG38746.1 AFG38746.1 AFG38750.1 AFG38750.1 AFG38779.1 AFG38779.1 AFG38780.1 AFG38780.1 leuB leuB hisA hisA AFG38787.1 AFG38787.1 AFG38788.1 AFG38788.1 AFG38796.1 AFG38796.1 AFG38842.1 AFG38842.1 AFG38849.1 AFG38849.1 panD panD panC panC panB panB aroC aroC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (387 aa)
AFG36139.1dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (353 aa)
AFG36140.1Glucose-1-phosphate thymidylyltransferase, short form; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (290 aa)
AFG36148.1Glycosyltransferase; PFAM: Glycosyl transferases group 1. (368 aa)
AFG36190.1Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (362 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa)
purLPhosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and [...] (1017 aa)
AFG36198.1Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein; TIGRFAM: phosphoribosylformylglycinamidine synthase I. (262 aa)
AFG36210.1PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase. (660 aa)
AFG36218.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (268 aa)
AFG36219.1Glycosidase; PFAM: Alpha amylase, catalytic domain. (457 aa)
AFG36229.1Glycosidase; PFAM: Alpha amylase, catalytic domain. (573 aa)
AFG36235.1Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain. (279 aa)
AFG36236.1Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (322 aa)
AFG36237.1PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family. (163 aa)
AFG36239.1PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit. (408 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
AFG36246.1PFAM: NADPH-dependent FMN reductase; TIGRFAM: NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family. (206 aa)
AFG36275.1Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; TIGRFAM: pyruvate, phosphate dikinase. (867 aa)
pgiPFAM: Phosphoglucose isomerase; Belongs to the GPI family. (550 aa)
argGPFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (425 aa)
AFG36301.1PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (420 aa)
AFG36302.1PFAM: Amino acid kinase family; TIGRFAM: acetylglutamate kinase. (263 aa)
argCAcetylglutamate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (372 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (494 aa)
AFG36321.1Serine acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase. (314 aa)
AFG36350.1PFAM: Inositol monophosphatase family. (282 aa)
AFG36355.1PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase. (313 aa)
AFG36356.13-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa)
AFG36368.1UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase. (281 aa)
AFG36396.1PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; Belongs to the glycosyl hydrolase 3 family. (779 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (244 aa)
AFG36411.1Malto-oligosyltrehalose synthase; PFAM: Alpha amylase, catalytic domain; TIGRFAM: malto-oligosyltrehalose synthase. (970 aa)
AFG36412.1Malto-oligosyltrehalose trehalohydrolase; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; Domain of unknown function (DUF3459); TIGRFAM: malto-oligosyltrehalose trehalohydrolase. (613 aa)
AFG36431.1Putative dehydrogenase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase. (504 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (353 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (150 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (166 aa)
AFG36462.1Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase; PFAM: Glycosyl hydrolase family 1; Belongs to the glycosyl hydrolase 1 family. (431 aa)
AFG36465.1Threonine aldolase; PFAM: Beta-eliminating lyase. (343 aa)
AFG36477.1PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: mevalonate kinase. (337 aa)
AFG36479.1PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. (328 aa)
AFG36480.1PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family. (441 aa)
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (368 aa)
AFG36482.13-hydroxy-3-methylglutaryl CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal; TIGRFAM: 3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade. (426 aa)
AFG36499.1Flavodoxin. (157 aa)
AFG36515.1PFAM: Aminotransferase class I and II. (435 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (309 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (242 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (320 aa)
AFG36569.1Galactose mutarotase-like enzyme; Converts alpha-aldose to the beta-anomer. (343 aa)
AFG36578.1Glycosidase; PFAM: Alpha amylase, catalytic domain; Domain of unknown function (DUF1939). (577 aa)
purKPhosphoribosylaminoimidazole carboxylase (NCAIR synthetase); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. (446 aa)
purEPhosphoribosylaminoimidazole carboxylase, PurE protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (167 aa)
AFG36584.1Glycine dehydrogenase, decarboxylating; PFAM: Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating); glycine cleavage system T protein; Belongs to the GcvT family. (1340 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (364 aa)
AFG36593.15-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1312 aa)
AFG36625.1Glycosyltransferase; PFAM: Glycogen synthase. (607 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (497 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (546 aa)
AFG36641.1Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric. (1066 aa)
AFG36695.1PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. (457 aa)
AFG36696.1PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (non-peptidoglycan organisms); Belongs to the aspartate-semialdehyde dehydrogenase family. (346 aa)
AFG36722.1Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (357 aa)
AFG36750.1Saccharopine dehydrogenase-like oxidoreductase; PFAM: Saccharopine dehydrogenase. (403 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
AFG36776.1PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (366 aa)
AFG36777.1PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. (364 aa)
AFG36778.1L-asparaginase/GlutRNAGln amidotransferase subunit D; PFAM: Asparaginase. (186 aa)
AFG36788.1PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase. (510 aa)
AFG36789.1Trehalose synthase; PFAM: Alpha amylase, catalytic domain; TIGRFAM: trehalose synthase-fused probable maltokinase; trehalose synthase. (1109 aa)
AFG36790.1Glycosidase; PFAM: Alpha amylase, catalytic domain. (621 aa)
AFG36793.1Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (835 aa)
ilvAThreonine ammonia-lyase, biosynthetic, long form; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (506 aa)
AFG36867.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain. (470 aa)
AFG36869.1Glycosidase; PFAM: Alpha amylase, catalytic domain. (500 aa)
AFG36881.1ADP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (434 aa)
glgAGlycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (474 aa)
ribAGTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (236 aa)
AFG36923.1Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I. (591 aa)
AFG36982.1Glycosidase; PFAM: Alpha amylase, catalytic domain; S-layer homology domain; Domain of unknown function (DUF1939). (705 aa)
AFG36983.1Phytoene dehydrogenase-like oxidoreductase; PFAM: Flavin containing amine oxidoreductase. (498 aa)
hisCPFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (360 aa)
AFG37077.1Glycosidase; PFAM: Alpha amylase, catalytic domain. (478 aa)
AFG37082.1Glycosidase; PFAM: Alpha amylase, catalytic domain. (623 aa)
AFG37109.1Flavodoxin. (158 aa)
AFG37134.1PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (248 aa)
AFG37140.1Hypothetical protein; PFAM: Domain of unknown function (DUF1925); Glycosyl hydrolase family 57; Domain of unknown function (DUF1926). (652 aa)
AFG37152.1Putative dehydrogenase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase. (487 aa)
miaAtRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (318 aa)
AFG37175.1Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (227 aa)
AFG37192.1Glycosidase; PFAM: Alpha amylase, N-terminal ig-like domain; Alpha amylase, catalytic domain; Belongs to the glycosyl hydrolase 13 family. (633 aa)
AFG37221.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (311 aa)
AFG37235.1Fructose-2,6-bisphosphatase; PFAM: Phosphoglycerate mutase family. (238 aa)
AFG37251.1Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (439 aa)
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (554 aa)
AFG37253.1Pullulanase-like glycosidase possibly secreted by type II secretory pathway; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Belongs to the glycosyl hydrolase 13 family. (665 aa)
AFG37258.1PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I; manually curated. (420 aa)
AFG37266.1Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (276 aa)
AFG37272.1Arginine deiminase; PFAM: Amidinotransferase. (418 aa)
AFG37273.1UDP-forming alpha,alpha-trehalose-phosphate synthase; PFAM: Trehalose-phosphatase; Glycosyltransferase family 20; TIGRFAM: trehalose-phosphatase; alpha,alpha-trehalose-phosphate synthase [UDP-forming]; HAD-superfamily hydrolase, subfamily IIB. (738 aa)
AFG37304.1PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (745 aa)
AFG37312.1TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. (158 aa)
AFG37339.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (370 aa)
AFG37343.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
AFG37346.1Amino-acid N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; Amino acid kinase family; TIGRFAM: amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. (435 aa)
AFG37353.1PFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; Belongs to the bacterial glucokinase family. (348 aa)
AFG37358.1Beta-fructosidase, levanase/invertase; PFAM: Glycosyl hydrolases family 32 N-terminal domain. (465 aa)
AFG37360.1PFAM: Lycopene cyclase protein. (385 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (158 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (225 aa)
AFG37398.1PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. (219 aa)
AFG37399.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (388 aa)
asnAPFAM: Aspartate-ammonia ligase; TIGRFAM: aspartate--ammonia ligase, AsnA-type. (343 aa)
AFG37414.11,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase family. (299 aa)
AFG37476.1Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase. (251 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
fabVPutative paraquat-inducible protein B; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA); Belongs to the TER reductase family. (399 aa)
AFG37544.1Transcriptional regulator/sugar kinase; PFAM: ROK family. (298 aa)
AFG37553.1PFAM: Chorismate mutase type I; TIGRFAM: monofunctional chorismate mutase, gram positive type, clade 1. (132 aa)
AFG37581.1PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (362 aa)
AFG37585.1PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
AFG37596.1PFAM: FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase. (260 aa)
AFG37618.1PFAM: Inositol monophosphatase family; TIGRFAM: histidinol-phosphate phosphatase HisN, inositol monophosphatase family. (263 aa)
guaBInosine-5''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (480 aa)
AFG37669.1PFAM: Lyase. (477 aa)
AFG37674.1AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme. (413 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
pgkPFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (392 aa)
AFG37691.1PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
AFG37718.1Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (359 aa)
AFG37719.1Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. (289 aa)
AFG37721.1Acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type. (571 aa)
AFG37722.1PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit. (171 aa)
ilvDPFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (558 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa)
AFG37760.1Putative NADPH-quinone reductase (modulator of drug activity B); PFAM: Flavodoxin-like fold. (198 aa)
dapLLL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (408 aa)
AFG37795.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
AFG37840.1Phosphoserine phosphatase SerB; PFAM: ACT domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. (408 aa)
AFG37857.1Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (465 aa)
AFG37858.1PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form. (459 aa)
AFG37859.1Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (323 aa)
pdhAPyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (334 aa)
AFG37869.1PFAM: Fumarase C C-terminus; Lyase. (458 aa)
aroK-2Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (190 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa)
AFG37943.1PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit. (487 aa)
AFG37944.1PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. (1540 aa)
AFG37948.1PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (538 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (488 aa)
AFG37976.1PFAM: Aminotransferase class I and II. (407 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (254 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (473 aa)
purMPhosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase. (315 aa)
purNFolate-dependent phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (194 aa)
purDPhosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. (416 aa)
AFG38034.1Putative membrane protein; PFAM: Heptaprenyl diphosphate synthase component I. (185 aa)
AFG38039.1Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (237 aa)
AFG38040.1Putative CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family. (288 aa)
AFG38051.1PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (592 aa)
argHPFAM: Lyase; TIGRFAM: argininosuccinate lyase. (453 aa)
AFG38077.1PFAM: 3-dehydroquinate synthase. (366 aa)
AFG38088.1Glycogen debranching enzyme GlgX; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: glycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase 13 family. (722 aa)
AFG38093.1Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. (307 aa)
AFG38096.1Pullulanase-like glycosidase possibly secreted by type II secretory pathway; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; Belongs to the glycosyl hydrolase 13 family. (787 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (460 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa)
AFG38100.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (355 aa)
AFG38101.1Acetylornithine deacetylase ArgE; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase (ArgE). (390 aa)
AFG38173.1Hypothetical protein; PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57; Belongs to the glycosyl hydrolase 57 family. (544 aa)
AFG38184.1Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase; PFAM: Aminotransferase class I and II. (439 aa)
adkAdenylate kinase family protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (210 aa)
AFG38195.1PFAM: Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (858 aa)
AFG38207.1Beta-galactosidase; PFAM: Glycosyl hydrolase family 1; TIGRFAM: beta-galactosidase. (449 aa)
AFG38232.1PFAM: Shikimate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family. (167 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (253 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa)
AFG38249.1acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit. (439 aa)
AFG38250.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (172 aa)
AFG38265.1ATP phosphoribosyltransferase involved in histidine biosynthesis. (358 aa)
AFG38266.1ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (206 aa)
hisBPFAM: Imidazoleglycerol-phosphate dehydratase. (199 aa)
AFG38278.1Transcriptional regulator with HTH domain and aminotransferase domain; PFAM: Aminotransferase class I and II. (397 aa)
AFG38298.1PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. (227 aa)
AFG38304.1Putative phosphatase; PFAM: haloacid dehalogenase-like hydrolase. (209 aa)
AFG38305.1Glycosidase; PFAM: Alpha amylase, catalytic domain; Domain of unknown function (DUF1939). (494 aa)
AFG38315.1Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase. (315 aa)
AFG38320.1Acyl carrier protein; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein. (82 aa)
AFG38323.1Methionine synthase II (cobalamin-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (808 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (320 aa)
AFG38334.1Methyltransferase family protein; PFAM: Methyltransferase domain. (246 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (478 aa)
AFG38377.1PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. (211 aa)
AFG38380.1Pullulanase-like glycosidase possibly secreted by type II secretory pathway; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: pullulanase, type I; Belongs to the glycosyl hydrolase 13 family. (921 aa)
AFG38383.1Glycosidase; PFAM: Alpha amylase, catalytic domain. (690 aa)
AFG38389.1Glycosidase; PFAM: Alpha amylase, catalytic domain; Domain of unknown function (DUF1939). (542 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (411 aa)
ilvD-2PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (613 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (554 aa)
AFG38447.1Putative phosphatase. (209 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (461 aa)
AFG38482.1Alcohol dehydrogenase, class IV; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (869 aa)
AFG38496.1PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (438 aa)
AFG38500.1phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (149 aa)
AFG38503.1Hypothetical protein; Manually curated. (328 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (259 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (206 aa)
glyAGlycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (429 aa)
AFG38523.1Trehalose/maltose hydrolase or phosphorylase; PFAM: Glycosyl hydrolase family 65 central catalytic domain; Glycosyl hydrolase family 65, N-terminal domain. (773 aa)
AFG38533.1Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III. (1209 aa)
AFG38535.1PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (212 aa)
AFG38551.1Glycosidase; PFAM: Alpha amylase, catalytic domain. (997 aa)
AFG38552.1Glycosidase; PFAM: Starch binding domain; Alpha amylase, catalytic domain; Domain of unknown function (DUF1939). (701 aa)
argJGlutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (424 aa)
AFG38576.1PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (464 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (247 aa)
trpB-2Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (413 aa)
trpDGlutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (549 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (469 aa)
AFG38592.1Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; PFAM: Aminotransferase class I and II. (407 aa)
AFG38618.1acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
AFG38631.1Glycogen debranching enzyme GlgX; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: glycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase 13 family. (718 aa)
AFG38653.1PFAM: Fatty acid hydroxylase superfamily. (190 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (437 aa)
AFG38669.1PFAM: Prephenate dehydratase; ACT domain; DAHP synthetase I family. (626 aa)
AFG38680.1TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein. (206 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (358 aa)
AFG38728.1PFAM: Citrate synthase; Belongs to the citrate synthase family. (472 aa)
AFG38731.1Phosphoglycerate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (389 aa)
AFG38746.1Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (320 aa)
AFG38750.1PFAM: Shikimate dehydrogenase substrate binding domain; Type I 3-dehydroquinase; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; 3-dehydroquinate dehydratase, type I. (509 aa)
AFG38779.1Fructose-2,6-bisphosphatase; PFAM: Phosphoglycerate mutase family. (232 aa)
AFG38780.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (659 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (362 aa)
hisAPFAM: Histidine biosynthesis protein; Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Belongs to the PRA-PH family. (463 aa)
AFG38787.1Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (434 aa)
AFG38788.1Aspartokinase; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (472 aa)
AFG38796.1Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase. (261 aa)
AFG38842.1Transcriptional regulator/sugar kinase; PFAM: ROK family. (327 aa)
AFG38849.1NADPH-dependent glutamate synthase, homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric. (509 aa)
panDL-aspartate-alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (114 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (295 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (275 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (351 aa)
Your Current Organism:
Spirochaeta africana
NCBI taxonomy Id: 889378
Other names: S. africana DSM 8902, Spirochaeta africana DSM 8902, Spirochaeta africana Z-7692, Spirochaeta africana str. DSM 8902, Spirochaeta africana strain DSM 8902
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