28 items (Columba livia) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	AMBP	Alpha-1-microglobulin/bikunin. (445 aa)
	PLAT	Plasminogen activator; Belongs to the peptidase S1 family. (557 aa)
	PROC	Protein C (Inactivator of coagulation factors Va and VIIIa), transcript variant X1. (433 aa)
	A306_00010588	Venom prothrombin activator porpharin-D-like. (618 aa)
	PROCR	Protein C receptor, endothelial. (223 aa)
	FGA	Fibrinogen alpha chain. (766 aa)
	FGB	Fibrinogen beta chain. (480 aa)
	FGG	Fibrinogen gamma chain. (436 aa)
	SERPINF2	Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (526 aa)
	APOH	Apolipoprotein H (Beta-2-glycoprotein I). (348 aa)
	SERPIND1	Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1; Belongs to the serpin family. (304 aa)
	THBD	Thrombomodulin. (204 aa)
	AHSG	Alpha-2-HS-glycoprotein. (338 aa)
	A306_00000007	Uncharacterized protein. (289 aa)
	SERPINE2	Glia-derived nexin isoform X2; Belongs to the serpin family. (436 aa)
	A306_00005714	Coagulation factor XIII B chain. (1158 aa)
	F3	Coagulation factor III (Thromboplastin, tissue factor). (272 aa)
	SERPINC1	Serpin peptidase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family. (502 aa)
	PLAU	Plasminogen activator, urokinase. (433 aa)
	TFPI	Tissue factor pathway inhibitor isoform X1. (338 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (609 aa)
	SERPINA10	Protein Z-dependent protease inhibitor isoform X1; Belongs to the serpin family. (461 aa)
	F10	Coagulation factor X; Belongs to the peptidase S1 family. (462 aa)
	F7	Coagulation factor VII (Serum prothrombin conversion accelerator). (425 aa)
	PROZ	Protein Z, vitamin K-dependent plasma glycoprotein; Belongs to the peptidase S1 family. (363 aa)
	A306_00000619	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (802 aa)
	A306_00000618	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (817 aa)
	F13A1	Coagulation factor XIII, A1 polypeptide. (595 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00000007	A306_00000618	A0A2I0MBK5	A0A2I0MV53	Uncharacterized protein.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.916
A306_00000007	A306_00000619	A0A2I0MBK5	A0A2I0MV52	Uncharacterized protein.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.916
A306_00000007	A306_00005714	A0A2I0MBK5	A0A2I0MDQ0	Uncharacterized protein.	Coagulation factor XIII B chain.	0.718
A306_00000007	AHSG	A0A2I0MBK5	A0A2I0MBF0	Uncharacterized protein.	Alpha-2-HS-glycoprotein.	0.786
A306_00000007	APOH	A0A2I0MBK5	A0A2I0M741	Uncharacterized protein.	Apolipoprotein H (Beta-2-glycoprotein I).	0.648
A306_00000007	F2	A0A2I0MBK5	A0A2I0MNE5	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.609
A306_00000007	FGA	A0A2I0MBK5	A0A2I0LXU7	Uncharacterized protein.	Fibrinogen alpha chain.	0.694
A306_00000007	FGB	A0A2I0MBK5	A0A2I0LXU9	Uncharacterized protein.	Fibrinogen beta chain.	0.548
A306_00000007	FGG	A0A2I0MBK5	A0A2I0LXV0	Uncharacterized protein.	Fibrinogen gamma chain.	0.605
A306_00000007	PLAT	A0A2I0MBK5	A0A2I0LJK9	Uncharacterized protein.	Plasminogen activator; Belongs to the peptidase S1 family.	0.601
A306_00000007	PLAU	A0A2I0MBK5	A0A2I0MFJ6	Uncharacterized protein.	Plasminogen activator, urokinase.	0.610
A306_00000007	PROC	A0A2I0MBK5	A0A2I0LTQ6	Uncharacterized protein.	Protein C (Inactivator of coagulation factors Va and VIIIa), transcript variant X1.	0.543
A306_00000007	SERPINC1	A0A2I0MBK5	A0A2I0MED6	Uncharacterized protein.	Serpin peptidase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.	0.599
A306_00000007	SERPIND1	A0A2I0MBK5	A0A2I0M850	Uncharacterized protein.	Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1; Belongs to the serpin family.	0.555
A306_00000007	SERPINF2	A0A2I0MBK5	A0A2I0M204	Uncharacterized protein.	Alpha-2-antiplasmin isoform X1; Belongs to the serpin family.	0.452
A306_00000618	A306_00000007	A0A2I0MV53	A0A2I0MBK5	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	Uncharacterized protein.	0.916
A306_00000618	A306_00000619	A0A2I0MV53	A0A2I0MV52	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.901
A306_00000618	A306_00005714	A0A2I0MV53	A0A2I0MDQ0	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	Coagulation factor XIII B chain.	0.427
A306_00000618	AHSG	A0A2I0MV53	A0A2I0MBF0	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	Alpha-2-HS-glycoprotein.	0.726
A306_00000618	AMBP	A0A2I0MV53	A0A2I0LJA1	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	Alpha-1-microglobulin/bikunin.	0.698