STRINGSTRING
TBX21 TBX21 PANX3 PANX3 CRTAM CRTAM DRD2 DRD2 IL18 IL18 CD14 CD14 TMEM173 TMEM173 SLC7A5 SLC7A5 NR1H4 NR1H4 CADM1 CADM1 A306_00011848 A306_00011848 A306_00011847 A306_00011847 CASP10 CASP10 IL12RB1 IL12RB1 A306_00013655 A306_00013655 A306_00013351 A306_00013351 TMEM106A TMEM106A BRCA1 BRCA1 A306_00013682 A306_00013682 A306_00000118 A306_00000118 A306_00013903 A306_00013903 DUSP15-2 DUSP15-2 CCBE1 CCBE1 CCR7 CCR7 HTR2B HTR2B TRAF6 TRAF6 A306_00000392 A306_00000392 A306_00000459 A306_00000459 A306_00000373 A306_00000373 A306_00000498 A306_00000498 A306_00000359 A306_00000359 POLR3D POLR3D ZFPM1 ZFPM1 A306_00014478 A306_00014478 A306_00000152 A306_00000152 BSG BSG A306_00014655 A306_00014655 SCRIB SCRIB A306_00014013 A306_00014013 DHX58 DHX58 A306_00014037 A306_00014037 SETD2 SETD2 MALT1 MALT1 ARID5A ARID5A A306_00014015 A306_00014015 A306_00014012 A306_00014012 IL1B IL1B NOD1 NOD1 RIPK2 RIPK2 RIPK1 RIPK1 FAM49B FAM49B RIOK3 RIOK3 SULF1 SULF1 A306_00000010 A306_00000010 LY96 LY96 CD83 CD83 LRRC1 LRRC1 RSAD2 RSAD2 A306_00001143 A306_00001143 A306_00001142 A306_00001142 AKIRIN2 AKIRIN2 MAP3K7 MAP3K7 ADAM17 ADAM17 MB21D1 MB21D1 AKAP12 AKAP12 NMBR NMBR IFNGR1 IFNGR1 TOMM70 TOMM70 HHLA2 HHLA2 LACC1 LACC1 APP APP PIBF1 PIBF1 CD58 CD58 IL18R1 IL18R1 IL1RL1 IL1RL1 IL1R1 IL1R1 A306_00003031 A306_00003031 ZBTB20 ZBTB20 A306_00002871 A306_00002871 SETD4 SETD4 CD2 CD2 RFTN1 RFTN1 IL6 IL6 C1QTNF4 C1QTNF4 RASGRP1 RASGRP1 THBS1 THBS1 BATF BATF PSEN1 PSEN1 TMED10 TMED10 SPON2 SPON2 HMGB2 HMGB2 TLR3 TLR3 KIT KIT EIF2AK3 EIF2AK3 MAVS MAVS GAPDH GAPDH CRLF2 CRLF2 TLR7 TLR7 VTCN1 VTCN1 A306_00003736 A306_00003736 POLR3B POLR3B IL17RA IL17RA NFAM1 NFAM1 ATF4 ATF4 WNT2 WNT2 PLA2R1 PLA2R1 IFIH1 IFIH1 IRF7 IRF7 FADD FADD ABCC8 ABCC8 A306_00007180 A306_00007180 LRRK2 LRRK2 GATA3 GATA3 A306_00007179 A306_00007179 PANX2 PANX2 HGF HGF IL21 IL21 IL15 IL15 EREG EREG A306_00007935 A306_00007935 A306_00007934 A306_00007934 A306_00005222 A306_00005222 A306_00005221 A306_00005221 SIRT1 SIRT1 PTPRC PTPRC BCL10 BCL10 MCOLN2 MCOLN2 GLMN GLMN F3 F3 DENND1B DENND1B IL16 IL16 USP50 USP50 IL23R IL23R DHX9 DHX9 IL12RB2 IL12RB2 ABL2 ABL2 IL12B IL12B FLT4 FLT4 CSF1R CSF1R CD74 CD74 TMF1 TMF1 XBP1 XBP1 CEBPG CEBPG SPHK1 SPHK1 SEMA7A SEMA7A A306_00006842 A306_00006842 CD276 CD276 A306_00006774 A306_00006774 CEBPB CEBPB DDX58 DDX58 FST FST IL6ST IL6ST TLR5 TLR5 IL20RB IL20RB ABL1 ABL1 CARD9 CARD9 AGPAT2 AGPAT2 C5 C5 RPS3 RPS3 WNT11 WNT11 CD40 CD40 ARFGEF2 ARFGEF2 SULF2 SULF2 SERPINF2 SERPINF2 HSPB1 HSPB1 DHX33 DHX33 DHX36 DHX36 IL12A IL12A ANKRD42 ANKRD42 CARD11 CARD11 IRF8 IRF8 A306_00009652 A306_00009652 CD34 CD34 A306_00007333 A306_00007333 MAPKAPK2 MAPKAPK2 IL10 IL10 WNT2B WNT2B RAB7B RAB7B LURAP1 LURAP1 ADORA2B ADORA2B NOS2 NOS2 NLRC4 NLRC4 EIF2AK2 EIF2AK2 A306_00010427 A306_00010427 C3AR1 C3AR1 HSPD1 HSPD1 IRF5 IRF5 G3BP1 G3BP1 TRIM32 TRIM32 TLR4 TLR4 ADIPOQ ADIPOQ PANX1 PANX1 TIRAP TIRAP POU2AF1 POU2AF1 POLR3F POLR3F APPL1 APPL1 PTGER4 PTGER4 EGR1 EGR1 PELI1 PELI1 A306_00011173 A306_00011173
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX21T-box 21. (168 aa)
PANX3Pannexin 3. (347 aa)
CRTAMCytotoxic and regulatory T cell molecule. (531 aa)
DRD2Dopamine receptor D2, transcript variant X1; Belongs to the G-protein coupled receptor 1 family. (447 aa)
IL18Interleukin-18. (196 aa)
CD14CD14 molecule. (416 aa)
TMEM173Transmembrane protein 173. (384 aa)
SLC7A5Solute carrier family 7 (Amino acid transporter light chain, L system), member 5. (512 aa)
NR1H4Nuclear receptor subfamily 1, group H, member 4, transcript variant X1. (477 aa)
CADM1Cell adhesion molecule 1. (617 aa)
A306_00011848Caspase-8, transcript variant X1; Belongs to the peptidase C14A family. (455 aa)
A306_00011847Caspase-8, transcript variant X2; Belongs to the peptidase C14A family. (464 aa)
CASP10Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (443 aa)
IL12RB1Interleukin 12 receptor, beta 1. (666 aa)
A306_00013655Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like. (514 aa)
A306_000133511-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (269 aa)
TMEM106ATransmembrane protein 106A. (261 aa)
BRCA1Breast cancer 1, early onset. (1734 aa)
A306_00013682Signaling lymphocytic activation molecule. (368 aa)
A306_00000118RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (514 aa)
A306_00013903Rho guanine nucleotide exchange factor 2-like. (322 aa)
DUSP15-2Interferon regulatory factor 4. (422 aa)
CCBE1Collagen and calcium binding EGF domains 1. (366 aa)
CCR7Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family. (373 aa)
HTR2B5-hydroxytryptamine (Serotonin) receptor 2B, G protein-coupled. (463 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
A306_00000392Uncharacterized protein. (261 aa)
A306_00000459SCY domain-containing protein. (126 aa)
A306_00000373CASPASE_P20 domain-containing protein. (209 aa)
A306_00000498Ig-like domain-containing protein. (107 aa)
A306_00000359PHB domain-containing protein. (223 aa)
POLR3DPolymerase (RNA) III (DNA directed) polypeptide D, 44kDa. (346 aa)
ZFPM1Zinc finger protein, FOG family member 1. (420 aa)
A306_00014478Cytochrome b-245 light chain. (162 aa)
A306_00000152Uncharacterized protein. (218 aa)
BSGBasigin (Ok blood group). (259 aa)
A306_00014655Protein scribble homolog. (754 aa)
SCRIBScribbled planar cell polarity protein. (743 aa)
A306_00014013Mitogen-activated protein kinase. (182 aa)
DHX58DEXH (Asp-Glu-X-His) box polypeptide 58. (674 aa)
A306_00014037Cathelicidin-3. (149 aa)
SETD2SET domain containing 2. (1256 aa)
MALT1MALT1 paracaspase. (474 aa)
ARID5AAT rich interactive domain 5A (MRF1-like). (169 aa)
A306_00014015Mitogen-activated protein kinase. (167 aa)
A306_00014012Mitogen-activated protein kinase. (365 aa)
IL1BInterleukin-1; Belongs to the IL-1 family. (269 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (951 aa)
RIPK2Receptor-interacting serine-threonine kinase 2. (547 aa)
RIPK1Receptor (TNFRSF)-interacting serine-threonine kinase 1. (685 aa)
FAM49BFamily with sequence similarity 49, member B, transcript variant X1. (324 aa)
RIOK3Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (483 aa)
SULF1Extracellular sulfatase. (877 aa)
A306_00000010Uncharacterized protein. (153 aa)
LY96Lymphocyte antigen 96. (122 aa)
CD83CD83 molecule. (217 aa)
LRRC1Leucine rich repeat containing 1. (497 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (329 aa)
A306_00001143Interleukin-17F. (169 aa)
A306_00001142Interleukin-17A. (169 aa)
AKIRIN2Akirin 2. (112 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7, transcript variant X1. (194 aa)
ADAM17ADAM metallopeptidase domain 17. (768 aa)
MB21D1Mab-21 domain containing 1. (313 aa)
AKAP12A kinase (PRKA) anchor protein 12. (1944 aa)
NMBRNeuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (388 aa)
IFNGR1Interferon gamma receptor 1. (410 aa)
TOMM70TPR_REGION domain-containing protein. (515 aa)
HHLA2HERV-H LTR-associating 2, transcript variant X1. (351 aa)
LACC1Laccase (Multicopper oxidoreductase) domain containing 1. (437 aa)
APPAmyloid beta (A4) protein. (716 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (761 aa)
CD58CD58 molecule. (349 aa)
IL18R1Interleukin 18 receptor 1. (565 aa)
IL1RL1Interleukin 1 receptor-like 1. (551 aa)
IL1R1Interleukin 1 receptor, type I. (568 aa)
A306_00003031Interleukin-1 receptor type 1. (583 aa)
ZBTB20Zinc finger and BTB domain containing 20. (736 aa)
A306_00002871Ig-like domain-containing protein. (335 aa)
SETD4SET domain containing 4, transcript variant X1. (439 aa)
CD2CD2 molecule. (310 aa)
RFTN1Raftlin, lipid raft linker 1, transcript variant X1. (601 aa)
IL6Interleukin 6. (150 aa)
C1QTNF4C1q and tumor necrosis factor related protein 4. (362 aa)
RASGRP1RAS guanyl releasing protein 1 (Calcium and DAG-regulated). (840 aa)
THBS1Thrombospondin 1. (997 aa)
BATFBasic leucine zipper transcription factor, ATF-like. (180 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
TMED10Transmembrane p24 trafficking protein 10. (174 aa)
SPON2Spondin 2, extracellular matrix protein, transcript variant X1. (387 aa)
HMGB2High mobility group box 2. (207 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (895 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3. (1004 aa)
MAVSMitochondrial antiviral signaling protein. (632 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (327 aa)
CRLF2Cytokine receptor-like factor 2. (378 aa)
TLR7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1047 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (281 aa)
A306_00003736OX-2 membrane glycoprotein. (258 aa)
POLR3BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (900 aa)
IL17RAInterleukin 17 receptor A. (969 aa)
NFAM1NFAT activating protein with ITAM motif 1. (252 aa)
ATF4Activating transcription factor 4. (354 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (326 aa)
PLA2R1Phospholipase A2 receptor 1, 180kDa. (1392 aa)
IFIH1Interferon induced with helicase C domain 1. (981 aa)
IRF7Interferon regulatory factor 7. (530 aa)
FADDFas (TNFRSF6)-associated via death domain. (195 aa)
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 8. (1571 aa)
A306_00007180Mitogen-activated protein kinase. (221 aa)
LRRK2Leucine-rich repeat kinase 2. (2447 aa)
GATA3GATA binding protein 3, transcript variant X1. (444 aa)
A306_00007179Mitogen-activated protein kinase 11. (75 aa)
PANX2Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (619 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (145 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (321 aa)
EREGEpiregulin. (118 aa)
A306_00007935Annexin. (177 aa)
A306_00007934Annexin. (343 aa)
A306_00005222Nucleolar RNA helicase 2-like. (328 aa)
A306_00005221Nucleolar RNA helicase 2-like. (558 aa)
SIRT1Sirtuin 1, transcript variant X1. (606 aa)
PTPRCProtein tyrosine phosphatase, receptor type, C, transcript variant X1. (1247 aa)
BCL10B-cell CLL/lymphoma 10. (214 aa)
MCOLN2Mucolipin 2, transcript variant X1. (536 aa)
GLMNGlomulin, FKBP associated protein. (606 aa)
F3Coagulation factor III (Thromboplastin, tissue factor). (272 aa)
DENND1BDENN/MADD domain containing 1B. (847 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1477 aa)
USP50Ubiquitin carboxyl-terminal hydrolase. (420 aa)
IL23RInterleukin 23 receptor. (798 aa)
DHX9DEAH (Asp-Glu-Ala-His) box helicase 9. (1229 aa)
IL12RB2Interleukin 12 receptor, beta 2. (784 aa)
ABL2Tyrosine-protein kinase. (1051 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa)
FLT4Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1373 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (617 aa)
CD74CD74 molecule, major histocompatibility complex, class II invariant chain, transcript variant X1. (278 aa)
TMF1TATA element modulatory factor 1. (1069 aa)
XBP1X-box binding protein 1. (197 aa)
CEBPGCCAAT/enhancer binding protein (C/EBP), gamma. (150 aa)
SPHK1Sphingosine kinase 1. (400 aa)
SEMA7ASemaphorin 7A, GPI membrane anchor (John Milton Hagen blood group), transcript variant X1; Belongs to the semaphorin family. (633 aa)
A306_00006842Zona pellucida sperm-binding protein 3. (453 aa)
CD276CD276 molecule. (292 aa)
A306_00006774Zona pellucida sperm-binding protein 3. (434 aa)
CEBPBCCAAT/enhancer binding protein (C/EBP), beta. (218 aa)
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 58. (730 aa)
FSTFollistatin, transcript variant X1. (343 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
TLR5Toll-like receptor 5; Belongs to the Toll-like receptor family. (860 aa)
IL20RBInterleukin 20 receptor beta. (266 aa)
ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase. (448 aa)
CARD9Caspase recruitment domain family, member 9. (541 aa)
AGPAT21-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (248 aa)
C5Complement component 5. (1677 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CD40CD40 molecule, TNF receptor superfamily member 5. (276 aa)
ARFGEF2ADP-ribosylation factor guanine nucleotide-exchange factor 2 (Brefeldin A-inhibited). (1699 aa)
SULF2Extracellular sulfatase. (875 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (526 aa)
HSPB1Heat shock 27kDa protein 1; Belongs to the small heat shock protein (HSP20) family. (189 aa)
DHX33DEAH (Asp-Glu-Ala-His) box polypeptide 33. (597 aa)
DHX36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (968 aa)
IL12AInterleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (186 aa)
ANKRD42Ankyrin repeat domain 42. (546 aa)
CARD11Caspase recruitment domain family, member 11. (1169 aa)
IRF8Interferon regulatory factor 8. (427 aa)
A306_00009652Receptor-interacting serine/threonine-protein kinase 2. (541 aa)
CD34CD34 molecule, transcript variant X1. (364 aa)
A306_00007333Uncharacterized protein C1orf106. (266 aa)
MAPKAPK2Mitogen-activated protein kinase-activated protein kinase 2. (309 aa)
IL10Interleukin 10. (176 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
LURAP1Leucine rich adaptor protein 1. (276 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (352 aa)
NOS2Nitric oxide synthase 2, inducible. (944 aa)
NLRC4NLR family, CARD domain containing 4. (1031 aa)
EIF2AK2Eukaryotic translation initiation factor 2-alpha kinase 2. (609 aa)
A306_00010427Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (415 aa)
C3AR1Complement component 3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
HSPD1Heat shock 60kDa protein 1 (Chaperonin); Belongs to the chaperonin (HSP60) family. (567 aa)
IRF5Interferon regulatory factor 5. (343 aa)
G3BP1GTPase activating protein (SH3 domain) binding protein 1. (454 aa)
TRIM32Tripartite motif containing 32, transcript variant X1. (693 aa)
TLR4Toll-like receptor 4. (779 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (245 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (370 aa)
TIRAPToll-interleukin 1 receptor (TIR) domain containing adaptor protein, transcript variant X1. (207 aa)
POU2AF1POU class 2 associating factor 1. (257 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (314 aa)
APPL1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (704 aa)
PTGER4Prostaglandin E receptor 4 (Subtype EP4); Belongs to the G-protein coupled receptor 1 family. (505 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (480 aa)
PELI1Pellino E3 ubiquitin protein ligase 1. (454 aa)
A306_000111731-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (299 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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